HitPredict

Interactor 1: CHD4 (Q6PDQ2)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.-)
Gene: CHD4

Interactor 2: KDM1A (Q6ZQ88)
Lysine-specific histone demethylase 1A (EC 1.14.99.66) (BRAF35-HDAC complex protein BHC110) (Flavin-containing amine oxidase domain-containing protein 2)
Gene: KDM1A

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	26206133, 34709266, 22297846
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0032991 - protein-containing complex GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1915 Mm			1 853
+	Hs
		246604 CHD4_HUMAN (1-1915): 0: 1662: 97.76		KDM1A_HUMAN (1-853): 0: 1019: 98.12
+	Hs
		246563 CHD3_HUMAN (19-1908): 0: 1582: 67.77		KDM1A_HUMAN (1-853): 0: 1019: 98.12
+	Hs
		247000 CHD7_HUMAN (4-1734): 0: 795: 21.61		KDM1A_HUMAN (1-853): 0: 1019: 98.12
+	Hs
		246801 CHD6_HUMAN (211-1722): 0: 793: 23.71		KDM1A_HUMAN (1-853): 0: 1019: 98.12
+	Hs
		246965 CHD8_HUMAN (7-1734): 0: 753: 22.46		KDM1A_HUMAN (1-853): 0: 1019: 98.12
+	Hs
		160026 CHD1_HUMAN (526-1726): 0: 700: 29.22		KDM1A_HUMAN (1-853): 0: 1019: 98.12
+	Ce
		110298 LE418_CAEEL (78-1906): 0: 1172: 40.84		KDM1A_CAEEL (183-832): 1e-177: 533: 27.60
+	Sp
		1082698 HRP1_SCHPO (519-1695): 0: 696: 28.54		LSD2_SCHPO (42-845): 2.32e-157: 494: 16.53