HitPredict

Interactor 1: Q6PK50 (Q6PK50)
HSP90AB1 protein
Gene: HSP90AB1

Interactor 2: WSB2 (Q9NYS7)
WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)
Gene: WSB2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 351 Hs			1 404
+	Hs
		468668 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		FBXW7_HUMAN (1-177): 1.54e-35: 140: 12.43
+	Hs
		461786 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		FBXW7_HUMAN (1-177): 1.54e-35: 140: 12.43
+	Hs
		468239 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		WDR5_HUMAN (281-403): 5.8e-33: 128: 14.06
+	Hs
		468856 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		WSB2_HUMAN (243-404): 2.78e-21: 96.6: 14.85
+	Hs
		461987 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		WSB2_HUMAN (243-404): 2.78e-21: 96.6: 14.85
+	Hs
		468157 HS90B_HUMAN (1-345): 6.02e-174: 502: 100.00		LIS1_HUMAN (327-404): 5.33e-15: 78.1: 13.25
+	Hs
		461248 HS90A_HUMAN (1-350): 4.37e-172: 498: 84.92		LIS1_HUMAN (327-404): 5.33e-15: 78.1: 13.25
+	Hs
		573609 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		FBXW7_HUMAN (1-177): 1.54e-35: 140: 12.43
+	Cr
		68530 A8J1U1_CHLRE (9-349): 2.33e-164: 477: 66.37		MUT11_CHLRE (126-276): 1.62e-12: 70.1: 28.29
+	Sc
		392317 HSP82_YEAST (11-350): 7.75e-147: 432: 66.86		PWP2_YEAST (159-404): 4.08e-26: 112: 13.38
+	Sc
		393109 HSP82_YEAST (11-350): 7.75e-147: 432: 66.86		COPA_YEAST (229-401): 2.84e-25: 110: 13.48
+	Hs
		573420 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		WDR5_HUMAN (281-403): 5.8e-33: 128: 14.06
+	Ca
		515423 HSP90_CANAL (9-350): 9.59e-143: 422: 64.14		TUP1_CANAL (292-403): 4.17e-23: 102: 16.79
+	Sc
		392605 HSP82_YEAST (11-350): 7.75e-147: 432: 66.86		TAF5_YEAST (123-360): 7.34e-18: 87.8: 25.77
+	Sc
		579254 HSC82_YEAST (13-350): 7.72e-146: 430: 65.49		TAF5_YEAST (123-360): 7.34e-18: 87.8: 25.77
+	Hs
		573699 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		WSB2_HUMAN (243-404): 2.78e-21: 96.6: 14.85
+	Hs
		573372 ENPL_HUMAN (2-351): 5.57e-138: 412: 42.54		LIS1_HUMAN (327-404): 5.33e-15: 78.1: 13.25