Protein: WSB2
WD repeat and SOCS box-containing protein 2 (WSB-2) (CS box-containing WD protein)

Gene: WSB2
Organism: Homo sapiens
Interactions: 97
UniProt ID: Q9NYS7

Gene Ontology (top 5):
GO:0000209 - protein polyubiquitination
GO:0005829 - cytosol
GO:0035556 - intracellular signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1371884

CUL5
Cullin-5

4

20

High-throughput

0.900

High

1415886

DDA1
DET1- and DDB1-associated protein 1

3

3

High-throughput

0.855

High

1420891

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

3

17

High-throughput

0.855

High

1346959

SNIP1
Smad nuclear-interacting protein 1

3

4

High-throughput

0.662

High

1403937

CSF3R
Granulocyte colony-stimulating factor receptor

1

5

Small-scale

0.637

High

507396

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

10

High-throughput

0.628

High

1452785

ACINU
Apoptotic chromatin condensation inducer in the nucleus

2

16

High-throughput

0.628

High

1155834

EZH2
Histone-lysine N-methyltransferase EZH2

1

18

High-throughput

0.625

High

1452786

ISY1
Pre-mRNA-splicing factor ISY1 homolog

1

2

High-throughput

0.618

High

612321

ARF4
ADP-ribosylation factor 4

1

6

High-throughput

0.618

High

673974

RS12
Small ribosomal subunit protein eS12

1

6

High-throughput

0.618

High

876205

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.618

High

970144

RS16
Small ribosomal subunit protein uS9

1

8

High-throughput

0.618

High

975995

RL7A
Large ribosomal subunit protein eL8

1

10

High-throughput

0.618

High

984568

RL30
Large ribosomal subunit protein eL30

1

4

High-throughput

0.618

High

993003

RACK1
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

1350217

PREX1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein

1

9

High-throughput

0.618

High

1147295

ELOB
Elongin-B

2

2

High-throughput

0.611

High

1452783

PFD2
Prefoldin subunit 2

2

4

High-throughput

0.611

High

1060239

B2CL1
Bcl-2-like protein 1

2

2

High-throughput

0.601

High

1452782

RBX2
RING-box protein 2

2

8

High-throughput

0.601

High

1358123

NUDC2
NudC domain-containing protein 2

2

17

High-throughput

0.584

High

1452787

NUDC
Nuclear migration protein nudC

2

17

High-throughput

0.584

High

719580

NKTR
NK-tumor recognition protein

2

3

High-throughput

0.574

High

1198676

NCBP3
Nuclear cap-binding protein subunit 3

2

1

High-throughput

0.574

High

1245428

ZC3HE
Zinc finger CCCH domain-containing protein 14

2

1

High-throughput

0.574

High

1324462

CLASR
CLK4-associating serine/arginine rich protein

2

1

High-throughput

0.574

High

1432371

PININ
Pinin

2

3

High-throughput

0.574

High

1452788

CCDC9
Coiled-coil domain-containing protein 9

2

1

High-throughput

0.574

High

1404682

PFD5
Prefoldin subunit 5

2

6

High-throughput

0.571

High

1115101

CUL4A
Cullin-4A

1

20

Small-scale

0.553

High

1157966

DDB1
DNA damage-binding protein 1

1

16

Small-scale

0.553

High

1212051

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

20

High-throughput

0.553

High

335193

ARI2
E3 ubiquitin-protein ligase ARIH2

1

13

High-throughput

0.536

High

1145406

RNPS1
RNA-binding protein with serine-rich domain 1

1

10

High-throughput

0.536

High

1308600

NUDC3
NudC domain-containing protein 3

2

17

High-throughput

0.533

High

1270346

SPT6H
Transcription elongation factor SPT6

1

5

High-throughput

0.489

High

1452563

BCLF1
Bcl-2-associated transcription factor 1

1

7

High-throughput

0.489

High

124849

AIP
AH receptor-interacting protein

1

13

High-throughput

0.479

High

144327

ACACB
Acetyl-CoA carboxylase 2

1

13

High-throughput

0.479

High

215354

TXNL1
Thioredoxin-like protein 1

1

14

High-throughput

0.479

High

226896

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

11

High-throughput

0.479

High

425966

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

18

High-throughput

0.479

High

461987

HS90A
Heat shock protein HSP 90-alpha

1

16

High-throughput

0.479

High

468856

HS90B
Heat shock protein HSP 90-beta

1

17

High-throughput

0.479

High

480912

LEG1
Galectin-1

1

6

High-throughput

0.479

High

528364

THIO
Thioredoxin

1

8

High-throughput

0.479

High

573699

ENPL
Endoplasmin

1

16

High-throughput

0.479

High

637765

FLNA
Filamin-A

1

13

High-throughput

0.479

High

658442

RS3
Small ribosomal subunit protein uS3

1

7

High-throughput

0.479

High

731650

STIP1
Stress-induced-phosphoprotein 1

1

11

High-throughput

0.479

High

770317

RL22
Large ribosomal subunit protein eL22

1

3

High-throughput

0.479

High

824400

RL13A
Large ribosomal subunit protein uL13

1

6

High-throughput

0.479

High

860388

RS9
Small ribosomal subunit protein uS4

1

9

High-throughput

0.479

High

895970

F10A1
Hsc70-interacting protein

1

13

High-throughput

0.479

High

906201

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

3

High-throughput

0.479

High

935201

TERA
Transitional endoplasmic reticulum ATPase

1

7

High-throughput

0.479

High

963380

PFD3
Prefoldin subunit 3

1

5

High-throughput

0.479

High

972597

RS14
Small ribosomal subunit protein uS11

1

7

High-throughput

0.479

High

977394

RS4X
Small ribosomal subunit protein eS4, X isoform

1

4

High-throughput

0.479

High

985365

RL10A
Large ribosomal subunit protein uL1

1

12

High-throughput

0.479

High

985571

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.479

High

1036811

DSG1
Desmoglein-1

1

3

High-throughput

0.479

High

1106097

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

14

High-throughput

0.479

High

1161074

FSCN1
Fascin

1

1

High-throughput

0.479

High

1357357

PRUN2
Protein prune homolog 2

1

1

High-throughput

0.479

High

1437960

CYBP
Calcyclin-binding protein

1

1

High-throughput

0.479

High

1438812

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

18

High-throughput

0.479

High

1452784

FKBPL
FK506-binding protein-like

1

18

High-throughput

0.479

High

991111

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

0

High-throughput

0.458

High

1366600

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

417808

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.457

High

1447144

PFD4
Prefoldin subunit 4

1

5

High-throughput

0.445

High

76582

B4DYC6
cDNA FLJ60958, highly similar to Homo sapiens SGT1, suppressor of G2 allele of SKP1

1

1

High-throughput

0.437

High

182198

PFD6
Prefoldin subunit 6

1

6

High-throughput

0.437

High

191843

MAGB2
Melanoma-associated antigen B2

1

8

High-throughput

0.437

High

209126

CYB5B
Cytochrome b5 type B

1

1

High-throughput

0.437

High

346690

TTC4
Tetratricopeptide repeat protein 4

1

16

High-throughput

0.437

High

587827

DESP
Desmoplakin

1

17

High-throughput

0.437

High

641049

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

8

High-throughput

0.437

High

903812

SSRD
Translocon-associated protein subunit delta

1

1

High-throughput

0.437

High

1037420

H11
Histone H1.1

1

9

High-throughput

0.437

High

1044387

HSF2
Heat shock factor protein 2

1

6

High-throughput

0.437

High

1142414

PDIA6
Protein disulfide-isomerase A6

1

9

High-throughput

0.437

High

1213852

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.437

High

1245580

Q6PK50
HSP90AB1 protein

1

17

High-throughput

0.437

High

1371205

GLMN
Glomulin

1

2

High-throughput

0.437

High

1384542

Q96BE0
Heat shock cognate 71 kDa protein

1

8

High-throughput

0.437

High

1406071

PHB2
Prohibitin-2

1

7

High-throughput

0.437

High

1409572

Q9BPW0
Serine/threonine-protein phosphatase

1

6

High-throughput

0.437

High

1413500

AASD1
Alanyl-tRNA editing protein Aarsd1

1

4

High-throughput

0.437

High

1414481

DERL1
Derlin-1

1

2

High-throughput

0.437

High

1438143

IL21R
Interleukin-21 receptor

1

3

Small-scale

0.437

High

1452789

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

4

High-throughput

0.437

High

455880

H10
Histone H1.0

1

0

High-throughput

0.249

Low

1397893

CCD42
Coiled-coil domain-containing protein 42

1

0

High-throughput

0.249

Low

1451968

NSMA3
Sphingomyelin phosphodiesterase 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025