Interactor 1: BTNL8 (Q6UX41)
Butyrophilin-like protein 8
Gene: BTNL8
Interactor 2: HHLA2 (Q9UM44)
HERV-H LTR-associating protein 2 (Human endogenous retrovirus-H long terminal repeat-associating protein 2)
Gene: HHLA2
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.61 | 1.00 | 0.783 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, unassigned1304 |
| Identification Methods | two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | C2-set_3~V-set, C1-set~PRY, C1-set~SPRY, C1-set~V-set, V-set~V-set |
| Common GO terms | GO:0001817 - regulation of cytokine production GO:0005102 - signaling receptor binding GO:0009897 - external side of plasma membrane GO:0050852 - T cell receptor signaling pathway |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025