Protein: BTNL8
Butyrophilin-like protein 8

Gene: BTNL8
Organism: Homo sapiens
Interactions: 47
UniProt ID: Q6UX41

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0002250 - adaptive immune response
GO:0005102 - signaling receptor binding
GO:0005886 - plasma membrane
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

296361

ATRN
Attractin

3

6

High-throughput

0.861

High

565412

ITA4
Integrin alpha-4

3

11

High-throughput

0.861

High

603794

ITA2
Integrin alpha-2

3

11

High-throughput

0.861

High

654981

ITA6
Integrin alpha-6

3

11

High-throughput

0.861

High

870823

GLRB
Glycine receptor subunit beta

3

3

High-throughput

0.861

High

871476

LEPR
Leptin receptor

3

6

High-throughput

0.861

High

922824

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

3

11

High-throughput

0.861

High

1116719

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

3

11

High-throughput

0.861

High

1249582

SCRB1
Scavenger receptor class B member 1

3

2

High-throughput

0.861

High

1249588

CNTP3
Contactin-associated protein-like 3

3

8

High-throughput

0.861

High

1249591

CNNM1
Metal transporter CNNM1

3

6

High-throughput

0.861

High

1249594

CA2D2
Voltage-dependent calcium channel subunit alpha-2/delta-2

3

2

High-throughput

0.861

High

935680

MFAP3
Microfibril-associated glycoprotein 3

3

0

High-throughput

0.816

High

175384

PLXB2
Plexin-B2

2

10

High-throughput

0.789

High

928784

CA2D1
Voltage-dependent calcium channel subunit alpha-2/delta-1

2

2

High-throughput

0.789

High

1101739

PTK7
Inactive tyrosine-protein kinase 7

2

3

High-throughput

0.789

High

1249583

HMR1
Major histocompatibility complex class I-related protein 1

2

6

High-throughput

0.789

High

1249590

CNNM2
Metal transporter CNNM2

2

6

High-throughput

0.789

High

138565

CLD5
Claudin-5

2

2

High-throughput

0.783

High

800296

INGR2
Interferon gamma receptor 2

2

8

High-throughput

0.783

High

1249575

MILR1
Allergin-1

2

5

High-throughput

0.783

High

1249597

HHLA2
HERV-H LTR-associating protein 2

2

13

High-throughput

0.783

High

1249580

NETO2
Neuropilin and tolloid-like protein 2

3

3

High-throughput

0.770

High

1249598

DJC16
DnaJ homolog subfamily C member 16

3

9

High-throughput

0.770

High

1249595

FPRP
Prostaglandin F2 receptor negative regulator

2

3

High-throughput

0.705

High

61117

T131L
Transmembrane protein 131-like

3

2

High-throughput

0.667

High

244472

MGRN1
E3 ubiquitin-protein ligase MGRN1

3

1

High-throughput

0.667

High

643368

OSBP1
Oxysterol-binding protein 1

3

2

High-throughput

0.667

High

1249584

OSBP2
Oxysterol-binding protein 2

3

2

High-throughput

0.667

High

1249592

T106B
Transmembrane protein 106B

3

1

High-throughput

0.667

High

1249596

LCAP
Leucyl-cystinyl aminopeptidase

3

0

High-throughput

0.638

High

1249573

BTNL3
Butyrophilin-like protein 3

1

18

Small-scale

0.618

High

1249578

TM87A
Transmembrane protein 87A

2

2

High-throughput

0.611

High

1249576

GOLI
E3 ubiquitin-protein ligase RNF130

3

7

High-throughput

0.609

High

1249579

RN149
E3 ubiquitin-protein ligase RNF149

3

6

High-throughput

0.609

High

1249585

TECT2
Tectonic-2

3

1

High-throughput

0.609

High

1249577

TM219
Insulin-like growth factor-binding protein 3 receptor

2

0

High-throughput

0.585

High

1249587

TM2D3
TM2 domain-containing protein 3

2

0

High-throughput

0.585

High

1249581

RHBL4
Rhomboid-related protein 4

2

1

High-throughput

0.558

High

404605

TFF1
Trefoil factor 1

1

1

Small-scale

0.528

High

1085330

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

11

High-throughput

0.437

High

1206268

NHLC3
NHL repeat-containing protein 3

1

3

High-throughput

0.437

High

1249586

TM87B
Transmembrane protein 87B

1

2

High-throughput

0.437

High

1249589

TM231
Transmembrane protein 231

3

0

High-throughput

0.347

High

1249574

PGAP1
GPI inositol-deacylase

1

0

High-throughput

0.249

Low

1249593

TM39A
Transmembrane protein 39A

1

0

High-throughput

0.249

Low

1249599

POMT1
Protein O-mannosyl-transferase 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025