HitPredict

Interactor 1: HIPPO (Q8T0S6)
Serine/threonine-protein kinase hippo (EC 2.7.11.1) (Drosophila homolog of MST1 and MST2) (STE20-like kinase MST) (dMST)
Gene: hpo

Interactor 2: MOB1 (Q95RA8)
MOB kinase activator-like 1 (Mob as tumor suppressor protein 1) (Dmob1) (Mps one binder kinase activator-like 1)
Gene: mats

Species: Drosophila melanogaster

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 0.60 0.683

The method score is based on:

Property Details
Experiments 29262338, 22215676, 26364751, 17347649
Identification Methods affinity chromatography technology, enzymatic study, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008285 - negative regulation of cell population proliferation
GO:0035329 - hippo signaling
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 669
Dm

1 219
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024