HitPredict

Interactor 1: RIN3 (Q8TB24)
Ras and Rab interactor 3 (Ras interaction/interference protein 3)
Gene: RIN3

Interactor 2: CD2AP (Q9Y5K6)
CD2-associated protein (Adapter protein CMS) (Cas ligand with multiple SH3 domains)
Gene: CD2AP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.581

Property	Details
Experiments	32552912
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0007165 - signal transduction GO:0030424 - axon GO:0030425 - dendrite GO:0031982 - vesicle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 985 Hs			1 639
+	Hs
		1251883 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		275213 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		GRAP2_HUMAN (2-329): 1.68e-45: 166: 12.83
+	Hs
		69536 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		B0LPF3_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		924717 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		70370 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		B2R6S4_HUMAN (113-378): 8.44e-21: 96.9: 14.24
+	Hs
		557745 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		1167810 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		DNMBP_HUMAN (113-602): 4.85e-17: 87.7: 15.23
+	Hs
		235552 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		VINEX_HUMAN (163-343): 4.52e-13: 74.2: 18.28
+	Hs
		1251932 RIN3_HUMAN (1-985): 1.3e-180: 552: 100.00		ITSN2_HUMAN (1-63): 2.7e-12: 72.2: 34.92
+	Hs
		166060 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		1357670 MACF1_HUMAN (588-905): 2.12e-44: 178: 15.92		CD2AP_HUMAN (1-639): 9.29e-139: 420: 100.00
+	Hs
		1155933 Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		166055 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		SH3K1_HUMAN (1-638): 3.71e-91: 297: 32.43
+	Hs
		166042 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		GRB2_HUMAN (112-328): 1.9e-40: 148: 18.27
+	Hs
		557717 Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		166030 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		NCK1_HUMAN (113-378): 9.79e-21: 96.5: 14.24
+	Hs
		1155937 Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19		ITSN2_HUMAN (1-63): 2.7e-12: 72.2: 34.92
+	Hs
		1078842 Q6NSK7_HUMAN (1-497): 1.57e-56: 213: 65.19		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64
+	Hs
		166056 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		ITSN2_HUMAN (1-63): 2.7e-12: 72.2: 34.92
+	Hs
		166049 SYNJ2_HUMAN (181-524): 2.35e-51: 199: 19.77		ITSN1_HUMAN (1-55): 3.97e-11: 68.8: 43.64