Protein: FANCI
Fanconi anemia group I protein (Protein FACI)

Gene: FANCI
Organism: Homo sapiens
Interactions: 201
UniProt ID: Q9NVI1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315879

FACD2
Fanconi anemia group D2 protein

22

3

Small-scale

0.988

High

1251243

WDR48
WD repeat-containing protein 48

3

1

Small-scale

0.861

High

1346600

FANCL
E3 ubiquitin-protein ligase FANCL

8

3

Small-scale

0.745

High

1346599

FANCI
Fanconi anemia group I protein

2

0

Small-scale

0.728

High

296348

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

4

1

Small-scale

0.694

High

1318202

UBL5
Ubiquitin-like protein 5

1

0

Small-scale

0.687

High

348026

MYC
Myc proto-oncogene protein

4

0

High-throughput

0.653

High

1033576

ILK
Integrin-linked protein kinase

3

0

High-throughput

0.643

High

1070789

RBBP5
Retinoblastoma-binding protein 5

1

1

High-throughput

0.618

High

1244523

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.618

High

206046

TGON2
Trans-Golgi network integral membrane protein 2

3

0

High-throughput

0.606

High

1288335

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.586

High

1299588

UHRF2
E3 ubiquitin-protein ligase UHRF2

1

0

Small-scale

0.586

High

1042647

CUL3
Cullin-3

2

0

High-throughput

0.585

High

918725

H2B1C
Histone H2B type 1-C/E/F/G/I

2

1

High-throughput

0.584

High

1346617

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

1

High-throughput

0.565

High

278170

PIAS1
E3 SUMO-protein ligase PIAS1

1

1

Small-scale

0.561

High

1222599

SLX4
Structure-specific endonuclease subunit SLX4

2

0

High-throughput

0.559

High

1346613

FAN1
Fanconi-associated nuclease 1

2

0

Small-scale

0.559

High

592530

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

385601

NTRK1
High affinity nerve growth factor receptor

2

5

High-throughput

0.543

High

682039

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

Small-scale

0.537

High

172253

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.536

High

355063

DQB1
HLA class II histocompatibility antigen, DQ beta 1 chain

1

2

High-throughput

0.536

High

488405

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.536

High

879854

TPTE
Putative tyrosine-protein phosphatase TPTE

1

1

High-throughput

0.536

High

1283468

SPSB4
SPRY domain-containing SOCS box protein 4

1

2

High-throughput

0.536

High

1301348

KKCC2
Calcium/calmodulin-dependent protein kinase kinase 2

1

1

High-throughput

0.536

High

1305211

SPSB2
SPRY domain-containing SOCS box protein 2

1

2

High-throughput

0.536

High

1326694

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

1

1

High-throughput

0.536

High

1346609

CLC2D
C-type lectin domain family 2 member D

1

2

High-throughput

0.536

High

1346610

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.536

High

260616

TP4A3
Protein tyrosine phosphatase type IVA 3

1

2

High-throughput

0.515

High

1335900

NEK6
Serine/threonine-protein kinase Nek6

1

1

High-throughput

0.515

High

199066

PAPS1
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1

1

0

High-throughput

0.513

High

212529

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

0

High-throughput

0.513

High

325423

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

High-throughput

0.513

High

349686

RASH
GTPase HRas

1

0

High-throughput

0.513

High

595573

GRAH
Granzyme H

1

0

High-throughput

0.513

High

728665

PPM1A
Protein phosphatase 1A

1

0

High-throughput

0.513

High

763114

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.513

High

848492

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

1030648

CLN3
Battenin

1

0

High-throughput

0.513

High

1079219

STXB2
Syntaxin-binding protein 2

1

0

High-throughput

0.513

High

1085522

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.513

High

1204209

CIR1
Corepressor interacting with RBPJ 1

1

0

High-throughput

0.513

High

1241919

ARRD4
Arrestin domain-containing protein 4

1

0

High-throughput

0.513

High

1253042

F174A
Membrane protein FAM174A

1

0

High-throughput

0.513

High

1255015

HELQ
Helicase POLQ-like

1

0

Small-scale

0.513

High

1264671

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.513

High

1294964

PKHA8
Pleckstrin homology domain-containing family A member 8

1

0

High-throughput

0.513

High

1318334

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

1318607

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.513

High

1346605

IMPCT
Protein IMPACT

1

0

High-throughput

0.513

High

1346612

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.513

High

1346616

LMBL1
Lethal(3)malignant brain tumor-like protein 1

1

0

High-throughput

0.513

High

1346619

NUBP2
Cytosolic Fe-S cluster assembly factor NUBP2

1

0

High-throughput

0.513

High

988143

RAD51
DNA repair protein RAD51 homolog 1

1

2

Small-scale

0.501

High

1038180

ATR
Serine/threonine-protein kinase ATR

1

1

Small-scale

0.501

High

339042

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.500

High

435779

IGF1R
Insulin-like growth factor 1 receptor

1

7

High-throughput

0.500

High

452489

PGFRB
Platelet-derived growth factor receptor beta

1

8

High-throughput

0.500

High

508224

FGFR1
Fibroblast growth factor receptor 1

1

10

High-throughput

0.500

High

601602

FGFR2
Fibroblast growth factor receptor 2

1

11

High-throughput

0.500

High

665668

EPHB2
Ephrin type-B receptor 2

1

4

High-throughput

0.500

High

872719

EPHA4
Ephrin type-A receptor 4

1

3

High-throughput

0.500

High

147565

SOCS6
Suppressor of cytokine signaling 6

1

0

High-throughput

0.493

High

1334978

BRF2
Transcription factor IIIB 50 kDa subunit

1

0

High-throughput

0.493

High

1346604

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.493

High

1346614

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

1346618

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.493

High

876204

PAR2
Proteinase-activated receptor 2

1

2

High-throughput

0.489

High

1020150

KLRB1
Killer cell lectin-like receptor subfamily B member 1

1

3

High-throughput

0.489

High

1028531

KLRD1
Natural killer cells antigen CD94

1

3

High-throughput

0.489

High

1030765

SLAF1
Signaling lymphocytic activation molecule

1

2

High-throughput

0.489

High

1067631

P2RY6
P2Y purinoceptor 6

1

3

High-throughput

0.489

High

1202749

P2RY8
P2Y purinoceptor 8

1

2

High-throughput

0.489

High

1085360

FSCN1
Fascin

1

0

Small-scale

0.483

High

395892

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

232997

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

2

Small-scale

0.479

High

241650

H2B1K
Histone H2B type 1-K

1

1

High-throughput

0.479

High

455925

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

584479

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

1

High-throughput

0.479

High

591421

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

1

High-throughput

0.479

High

627377

MCM3
DNA replication licensing factor MCM3

1

2

Small-scale

0.479

High

708783

MCM5
DNA replication licensing factor MCM5

1

1

Small-scale

0.479

High

729368

VGFR3
Vascular endothelial growth factor receptor 3

1

7

High-throughput

0.479

High

776406

MLH1
DNA mismatch repair protein Mlh1

1

1

Small-scale

0.479

High

832736

MCM2
DNA replication licensing factor MCM2

1

2

Small-scale

0.479

High

869893

PMS2
Mismatch repair endonuclease PMS2

1

1

Small-scale

0.479

High

935293

H31
Histone H3.1

1

1

High-throughput

0.479

High

952659

H33
Histone H3.3

1

1

High-throughput

0.479

High

985201

DUS2
Dual specificity protein phosphatase 2

1

1

High-throughput

0.479

High

1031624

ATM
Serine-protein kinase ATM

1

1

Small-scale

0.479

High

1035017

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

1123334

PKHG4
Puratrophin-1

1

1

High-throughput

0.479

High

1157501

FAP20
Fanconi anemia core complex-associated protein 20

1

1

High-throughput

0.479

High

1168422

LMTK1
Serine/threonine-protein kinase LMTK1

1

7

High-throughput

0.479

High

1172969

PHLP2
PH domain leucine-rich repeat-containing protein phosphatase 2

1

1

Small-scale

0.479

High

1231864

PIAS4
E3 SUMO-protein ligase PIAS4

1

1

Small-scale

0.479

High

1238076

CE120
Centrosomal protein of 120 kDa

1

1

High-throughput

0.479

High

1302683

RSF1
Remodeling and spacing factor 1

1

1

Small-scale

0.479

High

1313488

DUS26
Dual specificity protein phosphatase 26

1

1

High-throughput

0.479

High

1331424

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.479

High

847905

BRCA2
Breast cancer type 2 susceptibility protein

1

0

Small-scale

0.460

High

149350

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

151214

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

169629

BET1
BET1 homolog

1

0

High-throughput

0.458

High

245004

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

309099

KI20A
Kinesin-like protein KIF20A

1

0

High-throughput

0.458

High

314689

PARN
Poly(A)-specific ribonuclease PARN

1

0

High-throughput

0.458

High

442533

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

488814

ARAF
Serine/threonine-protein kinase A-Raf

1

0

Small-scale

0.458

High

546895

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.458

High

553858

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

555665

H2AX
Histone H2AX

1

0

High-throughput

0.458

High

622535

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

648905

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

652397

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

685052

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

721588

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

749893

BRCA1
Breast cancer type 1 susceptibility protein

1

0

High-throughput

0.458

High

780190

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

788926

RS27
Small ribosomal subunit protein eS27

1

0

High-throughput

0.458

High

839178

EMD
Emerin

1

0

High-throughput

0.458

High

868348

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

875359

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

897836

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

909204

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

916912

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

920365

RS24
Small ribosomal subunit protein eS24

1

0

High-throughput

0.458

High

922425

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

941487

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

967987

PO5F1
POU domain, class 5, transcription factor 1

1

0

High-throughput

0.458

High

1036133

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1039888

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.458

High

1045148

RUNX3
Runt-related transcription factor 3

1

0

Small-scale

0.458

High

1077349

T22D1
TSC22 domain family protein 1

1

0

High-throughput

0.458

High

1080397

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1085696

HIF1A
Hypoxia-inducible factor 1-alpha

1

0

High-throughput

0.458

High

1101331

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1108738

ANR55
Ankyrin repeat domain-containing protein 55

1

0

High-throughput

0.458

High

1148813

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1171946

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1191256

DPOLN
DNA polymerase nu

1

0

Small-scale

0.458

High

1221770

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1223014

FANCM
Fanconi anemia group M protein

1

0

Small-scale

0.458

High

1267191

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1268944

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1303002

MMS19
MMS19 nucleotide excision repair protein homolog

1

0

High-throughput

0.458

High

1303794

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.458

High

1310733

PELO
Protein pelota homolog

1

0

High-throughput

0.458

High

1326243

SENP6
Sentrin-specific protease 6

1

0

Small-scale

0.458

High

1332670

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1335152

PIDD1
p53-induced death domain-containing protein 1

1

0

Small-scale

0.458

High

1335335

RHOF
Rho-related GTP-binding protein RhoF

1

0

High-throughput

0.458

High

1342650

UBE2T
Ubiquitin-conjugating enzyme E2 T

1

0

Small-scale

0.458

High

1344496

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1346601

AKIP
Small ribosomal subunit protein mS38

1

0

High-throughput

0.458

High

1346602

TLS1
Splicing factor C9orf78

1

0

High-throughput

0.458

High

1346606

REV1
DNA repair protein REV1

1

0

Small-scale

0.458

High

1346607

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1346608

SEPT9
Septin-9

1

0

Small-scale

0.458

High

1346615

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

987299

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

7

High-throughput

0.457

High

1081622

NTRK3
NT-3 growth factor receptor

1

5

High-throughput

0.457

High

354581

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.445

High

572690

VGFR1
Vascular endothelial growth factor receptor 1

1

6

High-throughput

0.437

High

609573

FGFR3
Fibroblast growth factor receptor 3

1

9

High-throughput

0.437

High

674543

UFO
Tyrosine-protein kinase receptor UFO

1

7

High-throughput

0.437

High

738279

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

6

High-throughput

0.437

High

1222110

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

121031

APBB1
Amyloid beta precursor protein binding family B member 1

1

0

High-throughput

0.426

High

1022620

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

1057679

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

0

High-throughput

0.426

High

157

A0A024R6X4
PLEKHG4

1

1

High-throughput

0.407

High

99686

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.407

High

110847

H7C2E6
FA core complex associated protein 20

1

1

High-throughput

0.407

High

831729

CEBPA
CCAAT/enhancer-binding protein alpha

1

0

High-throughput

0.391

High

131975

UPK2
Uroplakin-2

1

0

High-throughput

0.279

Low

158682

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

1

0

High-throughput

0.279

Low

245430

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

945364

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

1254669

HUMMR
Protein MGARP

1

0

High-throughput

0.279

Low

1299259

OPALI
Opalin

1

0

High-throughput

0.279

Low

1328612

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

1332025

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

1343099

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1346611

LAMP3
Lysosome-associated membrane glycoprotein 3

1

0

High-throughput

0.279

Low

1313320

RCAF1
GEL complex subunit OPTI

1

0

High-throughput

0.269

Low

825750

MTR1B
Melatonin receptor type 1B

1

0

High-throughput

0.265

Low

519830

KCRU
Creatine kinase U-type, mitochondrial

1

0

High-throughput

0.249

Low

1124461

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

1165999

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1188933

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1198197

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

1298675

BROMI
Protein broad-minded

1

0

Small-scale

0.249

Low

1346603

HACD3
Very-long-chain

1

0

High-throughput

0.249

Low

1143

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

1241647

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024