HitPredict

Interactor 1: CC141 (Q6ZP82)
Coiled-coil domain-containing protein 141 (Coiled-coil protein associated with myosin II and DISC1)
Gene: CCDC141

Interactor 2: DISC1 (Q9NRI5)
Disrupted in schizophrenia 1 protein
Gene: DISC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.600

Property	Details
Experiments	12812986, 20956536
Identification Methods	two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1530 Hs			1 854
+	Mm
		98239 CC141_MOUSE (1-1530): 5.16e-104: 367: 72.65		DISC1_MOUSE (1-854): 0: 1251: 55.51
+	Hs
		1028894 SPTB2_HUMAN (103-1235): 5.18e-38: 158: 12.52		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		556961 MYH7_HUMAN (504-1408): 4.06e-22: 106: 11.37		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		238830 KALRN_HUMAN (860-1519): 8.39e-22: 105: 11.74		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		299582 TRIO_HUMAN (1212-1501): 1.68e-20: 101: 17.31		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		174813 SPTN2_HUMAN (104-1303): 5.69e-19: 96.1: 9.98		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		1448563 MACF1_HUMAN (325-1179): 1e-15: 85.9: 10.75		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		1117505 SPTN1_HUMAN (420-1252): 5.32e-14: 79.9: 9.71		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		773287 MYH10_HUMAN (670-1379): 4.13e-11: 70.5: 9.55		DISC1_HUMAN (18-854): 0: 1268: 100.00
+	Hs
		1040385 DYST_HUMAN (121-1133): 5.48e-11: 70.2: 13.52		DISC1_HUMAN (18-854): 0: 1268: 100.00