HitPredict - High confidence protein-protein interactions

Interactor 1: MRAP (Q8TCY5)
Melanocortin-2 receptor accessory protein (B27) (Fat cell-specific low molecular weight protein) (Fat tissue-specific low MW protein)
Gene: MRAP

Interactor 2: MRAP2 (Q96G30)
Melanocortin-2 receptor accessory protein 2 (MC2R accessory protein 2)
Gene: MRAP2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	0.60	0.576

Property	Details
Experiments	19329486, 20371771
Identification Methods	anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0030545 - signaling receptor regulator activity GO:0031780 - corticotropin hormone receptor binding and 9 others more... GO:0031781 - type 3 melanocortin receptor binding GO:0031782 - type 4 melanocortin receptor binding GO:0031783 - type 5 melanocortin receptor binding GO:0070996 - type 1 melanocortin receptor binding GO:0072659 - protein localization to plasma membrane GO:0106070 - regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0106071 - positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0106072 - negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:1903077 - negative regulation of protein localization to plasma membrane
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	172
Hs

1	205

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Last updated: 15 Jul 2024