HitPredict

Interactor 1: SP7 (Q8TDD2)
Transcription factor Sp7 (Zinc finger protein osterix)
Gene: SP7

Interactor 2: SIN3A (Q96ST3)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: SIN3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0003677 - DNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 431 Hs			1 1273
+	Hs
		1110307 SP6_HUMAN (67-376): 9.74e-93: 286: 39.51		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		250995 SP3_MOUSE (267-376): 6.59e-44: 165: 70.91		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Hs
		435159 SP1_HUMAN (195-410): 2.85e-40: 155: 46.30		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302481 KLF13_HUMAN (294-423): 7.5e-31: 121: 52.31		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Mm
		1141061 KLF13_MOUSE (294-423): 3.43e-31: 122: 52.31		SIN3A_MOUSE (1-1273): 0: 1542: 98.04
+	Hs
		1046653 KLF9_HUMAN (294-381): 4.19e-30: 118: 68.18		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1302437 KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		158009 KLF11_HUMAN (294-376): 2.04e-25: 110: 65.06		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		1024877 KLF10_HUMAN (294-376): 2.57e-25: 109: 66.27		SIN3A_HUMAN (1-1273): 0: 1545: 100.00
+	Hs
		257808 SP7_HUMAN (1-431): 1.9e-116: 348: 100.00		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257780 KLF9_HUMAN (294-381): 4.19e-30: 118: 68.18		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15
+	Hs
		257826 KLF16_HUMAN (294-383): 5.23e-30: 118: 66.67		SIN3B_HUMAN (20-331): 1.12e-13: 78.4: 16.15