HitPredict

Interactor 1: NEK7 (Q8TDX7)
Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)
Gene: NEK7

Interactor 2: PSPC1 (Q8WXF1)
Paraspeckle component 1 (Paraspeckle protein 1)
Gene: PSPC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 302 Hs			1 523
+	Rn
		1117299 AKT3_RAT (2-294): 1.41e-124: 366: 23.43		PSPC1_RAT (1-523): 9.19e-83: 268: 97.51
+	Rn
		1144336 AKT3_RAT (2-294): 1.41e-124: 366: 23.43		PABP1_RAT (4-522): 4.08e-69: 235: 14.16
+	Hs
		516486 STK4_HUMAN (4-292): 8.3e-105: 315: 27.93		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		681862 AKT1_HUMAN (6-294): 3.82e-124: 365: 23.05		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		160587 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		851499 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		NONO_HUMAN (50-523): 4.22e-68: 228: 57.60
+	Hs
		160753 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14
+	Hs
		516567 NEK10_HUMAN (31-288): 1.88e-46: 169: 33.71		PABP1_HUMAN (4-522): 4.65e-70: 237: 14.16
+	Hs
		613387 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		SFPQ_HUMAN (53-523): 3.05e-59: 210: 54.14
+	Hs
		851480 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		PABP4_HUMAN (3-149): 2.52e-27: 118: 18.83
+	Hs
		851506 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		ELAV1_HUMAN (84-156): 3.1e-13: 72.6: 29.11
+	Hs
		851668 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		RBM4_HUMAN (83-190): 4.98e-09: 60.1: 32.14