HitPredict

Interactor 1: ITPR1 (P11881)
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 (IP3 receptor isoform 1) (IP3R 1) (InsP3R1) (Inositol 1,4,5 trisphosphate receptor) (Inositol 1,4,5-trisphosphate receptor type 1) (Inositol 1,4,5-trisphosphate-binding protein P400) (Protein PCD-6) (Purkinje cell protein 1) (Type 1 inositol 1,4,5-trisphosphate receptor) (Type 1 InsP3 receptor)
Gene: ITPR1

Interactor 2: ERLN2 (Q8BFZ9)
Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) (Stomatin-prohibitin-flotillin-HflC/K domain-containing protein 2) (SPFH domain-containing protein 2)
Gene: Erlin2

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30135210, 21610068
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0032991 - protein-containing complex
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 2749 Mm			1 340
+	Rn
		78158 ITPR1_RAT (1-2749): 0: 4478: 99.56		ERLN2_RAT (1-340): 2.85e-120: 351: 98.24
+	Hs
		299900 ITPR1_HUMAN (1-2749): 0: 4458: 98.22		ERLN2_HUMAN (1-340): 9.4e-117: 342: 97.35
+	Mm
		515779 ITPR1_MOUSE (1-2749): 0: 4475: 100.00		ERLN1_MOUSE (1-332): 2.08e-105: 314: 74.78
+	Hs
		266152 ITPR1_HUMAN (1-2749): 0: 4458: 98.22		ERLN1_HUMAN (20-323): 3.1e-100: 301: 79.61