HitPredict

Interactor 1: NEK7 (Q8TDX7)
Serine/threonine-protein kinase Nek7 (EC 2.7.11.34) (Never in mitosis A-related kinase 7) (NimA-related protein kinase 7)
Gene: NEK7

Interactor 2: BICC1 (Q9H694)
Protein bicaudal C homolog 1 (Bic-C)
Gene: BICC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~SAM_1
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 302 Hs			1 974
+	Hs
		1147970 NEK6_HUMAN (12-302): 1.58e-139: 397: 81.44		ANKS6_HUMAN (608-960): 6.75e-62: 228: 20.61
+	Hs
		127939 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		IF2B3_HUMAN (13-436): 2.38e-68: 241: 14.22
+	Hs
		1147963 NEK7_HUMAN (1-302): 1.91e-124: 359: 100.00		ANKS6_HUMAN (608-960): 6.75e-62: 228: 20.61
+	Hs
		160813 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		IF2B1_HUMAN (13-407): 3.37e-67: 238: 15.85
+	Hs
		682197 AKT2_HUMAN (7-294): 2.03e-127: 373: 24.92		FUBP2_HUMAN (130-490): 6.32e-57: 211: 12.73
+	Hs
		681965 AKT1_HUMAN (6-294): 3.82e-124: 365: 23.05		FUBP2_HUMAN (130-490): 6.32e-57: 211: 12.73
+	Hs
		1255564 NEK7_HUMAN (1-302): 1.91e-124: 359: 100.00		FUBP2_HUMAN (130-490): 6.32e-57: 211: 12.73
+	Hs
		1027410 STK3_HUMAN (8-301): 3.15e-120: 355: 28.14		FUBP2_HUMAN (130-490): 6.32e-57: 211: 12.73
+	Hs
		160693 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		FUBP2_HUMAN (130-490): 6.32e-57: 211: 12.73
+	Hs
		1173316 NEK6_HUMAN (12-302): 1.58e-139: 397: 81.44		ANKS3_HUMAN (796-938): 5.69e-34: 141: 28.77
+	Hs
		1173306 NEK7_HUMAN (1-302): 1.91e-124: 359: 100.00		ANKS3_HUMAN (796-938): 5.69e-34: 141: 28.77
+	Hs
		160709 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		FUBP3_HUMAN (245-662): 4.27e-21: 100: 12.07
+	Hs
		128078 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		IF2B3_HUMAN (13-436): 2.38e-68: 241: 14.22
+	Hs
		851708 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		IF2B1_HUMAN (13-407): 3.37e-67: 238: 15.85
+	Hs
		160479 AURKA_HUMAN (2-301): 1.63e-118: 348: 26.30		HNRPK_HUMAN (131-206): 5.93e-13: 74.4: 18.42
+	Hs
		1147960 NEK8_HUMAN (40-288): 1.58e-51: 181: 40.40		ANKS6_HUMAN (608-960): 6.75e-62: 228: 20.61
+	Hs
		851621 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		FUBP2_HUMAN (130-490): 6.32e-57: 211: 12.73
+	Hs
		959385 STK4_HUMAN (4-292): 8.3e-105: 315: 27.93		VIGLN_HUMAN (219-425): 3.78e-11: 69.6: 15.53
+	Hs
		851501 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		PCBP2_HUMAN (217-595): 1.61e-22: 102: 12.21
+	Hs
		851500 NEK4_HUMAN (31-285): 1.86e-53: 188: 40.23		PCBP1_HUMAN (128-212): 4.11e-11: 67.8: 20.00