HitPredict

Interactor 1: TBA1A (Q71U36)
Tubulin alpha-1A chain (EC 3.6.5.-) (Alpha-tubulin 3) (Tubulin B-alpha-1) (Tubulin alpha-3 chain) [Cleaved into: Detyrosinated tubulin alpha-1A chain]
Gene: TUBA1A

Interactor 2: CPAP (Q9HC77)
Centrosomal P4.1-associated protein (Centromere protein J) (CENP-J) (Centrosome assembly and centriole elongation protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CPAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29568061, 27291054
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule GO:0007224 - smoothened signaling pathway GO:0046785 - microtubule polymerization and 1 others more... GO:0051301 - cell division
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 451 Hs			1 1338
+	Hs
		996864 TBA1B_HUMAN (1-440): 0: 712: 99.55		CPAP_HUMAN (1-1338): 3.17e-149: 488: 100.00
+	Hs
		997521 TBB4B_HUMAN (1-437): 0: 694: 40.50		CPAP_HUMAN (1-1338): 3.17e-149: 488: 100.00
+	Hs
		1143174 TBA1A_HUMAN (1-451): 0: 710: 100.00		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		1410566 TBA1C_HUMAN (1-451): 0: 722: 98.00		CP250_HUMAN (559-1267): 3.7e-11: 70.4: 9.54
+	Dm
		432159 TBA2_DROME (1-451): 0: 707: 94.68		MYSA_DROME (60-636): 7.76e-14: 79.3: 11.27
+	Hs
		996833 TBA1B_HUMAN (1-440): 0: 712: 99.55		CP250_HUMAN (559-1267): 3.7e-11: 70.4: 9.54
+	Hs
		1259469 TBA1A_HUMAN (1-451): 0: 710: 100.00		CP250_HUMAN (559-1267): 3.7e-11: 70.4: 9.54
+	Hs
		587710 TBA1A_HUMAN (1-451): 0: 710: 100.00		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82
+	Hs
		457662 TBB5_HUMAN (1-439): 0: 696: 40.77		CP250_HUMAN (559-1267): 3.7e-11: 70.4: 9.54
+	Hs
		997486 TBB4B_HUMAN (1-437): 0: 694: 40.50		CP250_HUMAN (559-1267): 3.7e-11: 70.4: 9.54