Protein: CPAP
Centrosomal P4.1-associated protein (Centromere protein J) (CENP-J) (Centrosome assembly and centriole elongation protein) (LAG-3-associated protein) (LYST-interacting protein 1)

Gene: CPAP
Organism: Homo sapiens
Interactions: 181
UniProt ID: Q9HC77

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0005737 - cytoplasm
GO:0005813 - centrosome
GO:0005814 - centriole
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1149377

STIL
SCL-interrupting locus protein

5

1

Small-scale

0.721

High

1438719

CPAP
Centrosomal P4.1-associated protein

1

16

Small-scale

0.716

High

966895

1433G
14-3-3 protein gamma

4

20

Small-scale

0.693

High

1049805

1433F
14-3-3 protein eta

4

20

High-throughput

0.691

High

1278219

CLAP1
CLIP-associating protein 1

4

2

High-throughput

0.686

High

1248201

SAS6
Spindle assembly abnormal protein 6 homolog

4

18

Small-scale

0.673

High

213254

CP110
Centriolar coiled-coil protein of 110 kDa

3

1

High-throughput

0.656

High

1438737

CP131
Centrosomal protein of 131 kDa

3

17

High-throughput

0.656

High

324216

CE152
Centrosomal protein of 152 kDa

3

17

Small-scale

0.646

High

920284

PLK1
Serine/threonine-protein kinase PLK1

3

5

High-throughput

0.640

High

1143541

PCM1
Pericentriolar material 1 protein

3

2

High-throughput

0.640

High

996864

TBA1B
Tubulin alpha-1B chain

2

10

Small-scale

0.639

High

1045791

TF65
Transcription factor p65

2

4

Small-scale

0.631

High

1226276

CP135
Centrosomal protein of 135 kDa

2

16

Small-scale

0.629

High

270981

CLAP2
CLIP-associating protein 2

2

1

High-throughput

0.628

High

1108720

TBB3
Tubulin beta-3 chain

2

11

High-throughput

0.628

High

990759

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.614

High

730261

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.611

High

972019

1433E
14-3-3 protein epsilon

2

4

High-throughput

0.611

High

1248115

CRTC3
CREB-regulated transcription coactivator 3

2

4

High-throughput

0.611

High

1350824

PKHO2
Pleckstrin homology domain-containing family O member 2

3

5

High-throughput

0.609

High

340242

PCNT
Pericentrin

2

19

High-throughput

0.584

High

655935

TBG1
Tubulin gamma-1 chain

2

19

Small-scale

0.584

High

755633

TTK
Dual specificity protein kinase TTK

2

7

High-throughput

0.584

High

1140890

KIF14
Kinesin-like protein KIF14

2

11

High-throughput

0.584

High

1241591

CEP85
Centrosomal protein of 85 kDa

2

17

High-throughput

0.584

High

1309498

CEP97
Centrosomal protein of 97 kDa

2

3

High-throughput

0.584

High

1331563

CE120
Centrosomal protein of 120 kDa

2

19

High-throughput

0.584

High

1340672

NEDD1
Protein NEDD1

2

8

High-throughput

0.584

High

1350185

ALMS1
Centrosome-associated protein ALMS1

2

7

High-throughput

0.584

High

1396818

SNX27
Sorting nexin-27

2

9

High-throughput

0.584

High

1411312

LZTS2
Leucine zipper putative tumor suppressor 2

2

19

High-throughput

0.584

High

1438738

TNR6B
Trinucleotide repeat-containing gene 6B protein

2

5

High-throughput

0.584

High

1438741

NINL
Ninein-like protein

2

17

High-throughput

0.584

High

1438726

BCCIP
BRCA2 and CDKN1A-interacting protein

2

0

High-throughput

0.580

High

539014

EPB41
Protein 4.1

1

6

Small-scale

0.573

High

136138

PLK4
Serine/threonine-protein kinase PLK4

2

16

Small-scale

0.571

High

1259516

TBA1A
Tubulin alpha-1A chain

2

10

High-throughput

0.571

High

1417958

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

9

High-throughput

0.541

High

483220

CLCA
Clathrin light chain A

1

4

High-throughput

0.536

High

997521

TBB4B
Tubulin beta-4B chain

1

11

High-throughput

0.536

High

1191986

TBB8
Tubulin beta-8 chain

1

11

High-throughput

0.536

High

1353048

GEMI5
Gem-associated protein 5

1

9

High-throughput

0.536

High

1417883

DUS16
Dual specificity protein phosphatase 16

1

7

High-throughput

0.536

High

1429707

KLC2
Kinesin light chain 2

1

6

High-throughput

0.536

High

1438722

DLRB1
Dynein light chain roadblock-type 1

1

1

High-throughput

0.536

High

1217765

GFI1B
Zinc finger protein Gfi-1b

1

1

High-throughput

0.523

High

1401398

CIC
Protein capicua homolog

1

12

High-throughput

0.523

High

1250786

MPRIP
Myosin phosphatase Rho-interacting protein

1

19

High-throughput

0.515

High

1250590

DPPA3
Developmental pluripotency-associated protein 3

1

0

High-throughput

0.513

High

1338179

PPHLN
Periphilin-1

1

0

High-throughput

0.513

High

1409897

SOSB1
SOSS complex subunit B1

1

0

High-throughput

0.513

High

1435314

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.513

High

928350

ATN1
Atrophin-1

1

6

High-throughput

0.508

High

1368487

CBP
CREB-binding protein

1

8

Small-scale

0.501

High

1237924

PHLB3
Pleckstrin homology-like domain family B member 3

1

18

High-throughput

0.489

High

1406459

LYST
Lysosomal-trafficking regulator

1

15

Small-scale

0.481

High

1438744

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

132516

CDC7
Cell division cycle 7-related protein kinase

1

20

High-throughput

0.479

High

159269

ABLM1
Actin-binding LIM protein 1

1

6

High-throughput

0.479

High

164101

NDC80
Kinetochore protein NDC80 homolog

1

16

High-throughput

0.479

High

175217

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.479

High

290161

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

299580

TRIO
Triple functional domain protein

1

20

High-throughput

0.479

High

332449

TNKS1
Poly [ADP-ribose] polymerase tankyrase-1

1

8

Small-scale

0.479

High

338548

SC24B
Protein transport protein Sec24B

1

3

High-throughput

0.479

High

349248

LATS1
Serine/threonine-protein kinase LATS1

1

20

High-throughput

0.479

High

401518

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.479

High

404436

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

414659

P53
Cellular tumor antigen p53

1

5

High-throughput

0.479

High

437349

K2C8
Keratin, type II cytoskeletal 8

1

8

High-throughput

0.479

High

479167

ENOG
Gamma-enolase

1

7

High-throughput

0.479

High

553283

KCRB
Creatine kinase B-type

1

3

High-throughput

0.479

High

630042

BTF3
Transcription factor BTF3

1

7

High-throughput

0.479

High

687305

HMGB2
High mobility group protein B2

1

8

High-throughput

0.479

High

702043

TMOD1
Tropomodulin-1

1

4

High-throughput

0.479

High

851425

PRS6B
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.479

High

943422

H2BFS
Histone H2B type F-S

1

13

High-throughput

0.479

High

1065767

CAMP2
Calmodulin-regulated spectrin-associated protein 2

1

16

High-throughput

0.479

High

1115615

ASPP2
Apoptosis-stimulating of p53 protein 2

1

11

High-throughput

0.479

High

1123827

DCTN1
Dynactin subunit 1

1

18

High-throughput

0.479

High

1135385

SLMAP
Sarcolemmal membrane-associated protein

1

19

High-throughput

0.479

High

1138075

TNIP1
TNFAIP3-interacting protein 1

1

18

High-throughput

0.479

High

1148947

SC23A
Protein transport protein Sec23A

1

3

High-throughput

0.479

High

1149029

SC23B
Protein transport protein Sec23B

1

3

High-throughput

0.479

High

1150085

MARE2
Microtubule-associated protein RP/EB family member 2

1

4

High-throughput

0.479

High

1157563

PKN2
Serine/threonine-protein kinase N2

1

9

High-throughput

0.479

High

1178636

KIF7
Kinesin-like protein KIF7

1

3

High-throughput

0.479

High

1193716

C2CD3
C2 domain-containing protein 3

1

1

High-throughput

0.479

High

1197093

AMOT
Angiomotin

1

19

High-throughput

0.479

High

1210995

CE170
Centrosomal protein of 170 kDa

1

14

High-throughput

0.479

High

1213195

CAMP1
Calmodulin-regulated spectrin-associated protein 1

1

1

High-throughput

0.479

High

1231882

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

1

High-throughput

0.479

High

1247002

RICTR
Rapamycin-insensitive companion of mTOR

1

5

High-throughput

0.479

High

1252238

SYNE3
Nesprin-3

1

20

High-throughput

0.479

High

1295567

MIB1
E3 ubiquitin-protein ligase MIB1

1

9

High-throughput

0.479

High

1308102

LRC49
Leucine-rich repeat-containing protein 49

1

7

High-throughput

0.479

High

1316192

DCP1B
mRNA-decapping enzyme 1B

1

3

High-throughput

0.479

High

1322452

SPICE
Spindle and centriole-associated protein 1

1

2

High-throughput

0.479

High

1326349

NIN
Ninein

1

19

High-throughput

0.479

High

1336848

TNR6A
Trinucleotide repeat-containing gene 6A protein

1

12

High-throughput

0.479

High

1338383

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1360088

PALLD
Palladin

1

9

High-throughput

0.479

High

1360825

ASB11
Ankyrin repeat and SOCS box protein 11

1

9

High-throughput

0.479

High

1371446

DVL3
Segment polarity protein dishevelled homolog DVL-3

1

6

High-throughput

0.479

High

1382778

FERM2
Fermitin family homolog 2

1

1

High-throughput

0.479

High

1385697

ENTR1
Endosome-associated-trafficking regulator 1

1

1

High-throughput

0.479

High

1386292

HAUS1
HAUS augmin-like complex subunit 1

1

1

High-throughput

0.479

High

1413269

TCHP
Trichoplein keratin filament-binding protein

1

15

High-throughput

0.479

High

1415631

RIOK2
Serine/threonine-protein kinase RIO2

1

2

High-throughput

0.479

High

1432929

UN45A
Protein unc-45 homolog A

1

11

High-throughput

0.479

High

1438721

RAB18
Ras-related protein Rab-18

1

2

High-throughput

0.479

High

1438724

LATS2
Serine/threonine-protein kinase LATS2

1

20

High-throughput

0.479

High

1438727

IBTK
Inhibitor of Bruton tyrosine kinase

1

7

High-throughput

0.479

High

1438728

WRP73
WD repeat-containing protein WRAP73

1

10

High-throughput

0.479

High

1438730

HDAC6
Protein deacetylase HDAC6

1

20

Small-scale

0.479

High

1438731

ZO2
Tight junction protein 2

1

2

High-throughput

0.479

High

1438732

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

3

High-throughput

0.479

High

1438733

TEKT2
Tektin-2

1

2

High-throughput

0.479

High

1438734

ANC2
Anaphase-promoting complex subunit 2

1

12

High-throughput

0.479

High

1438736

CSN3
COP9 signalosome complex subunit 3

1

1

High-throughput

0.479

High

1438739

MARE3
Microtubule-associated protein RP/EB family member 3

1

4

High-throughput

0.479

High

1438740

ADIP
Afadin- and alpha-actinin-binding protein

1

1

High-throughput

0.479

High

1438743

PHOCN
MOB-like protein phocein

1

3

High-throughput

0.479

High

1352427

SH3R2
E3 ubiquitin-protein ligase SH3RF2

1

5

High-throughput

0.470

High

616087

LAG3
Lymphocyte activation gene 3 protein

1

3

Small-scale

0.462

High

64126

CNOT1
CCR4-NOT transcription complex subunit 1

1

0

High-throughput

0.458

High

64775

RIMC1
RAB7A-interacting MON1-CCZ1 complex subunit 1

1

0

High-throughput

0.458

High

451640

GPX1
Glutathione peroxidase 1

1

0

High-throughput

0.458

High

720804

PUR8
Adenylosuccinate lyase

1

0

High-throughput

0.458

High

833688

NAA10
N-alpha-acetyltransferase 10

1

0

High-throughput

0.458

High

959259

ABCE1
ATP-binding cassette sub-family E member 1

1

0

High-throughput

0.458

High

1050824

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

0

High-throughput

0.458

High

1169037

CSPP1
Centrosome and spindle pole-associated protein 1

1

0

High-throughput

0.458

High

1178018

MOONR
Protein moonraker

1

0

High-throughput

0.458

High

1191614

RABL6
Rab-like protein 6

1

0

High-throughput

0.458

High

1198530

CEP55
Centrosomal protein of 55 kDa

1

0

High-throughput

0.458

High

1225385

WAC2A
WASH complex subunit 2A

1

0

High-throughput

0.458

High

1228573

HAUS3
HAUS augmin-like complex subunit 3

1

0

High-throughput

0.458

High

1256406

TPGS1
Tubulin polyglutamylase complex subunit 1

1

0

High-throughput

0.458

High

1278448

HAUS6
HAUS augmin-like complex subunit 6

1

0

High-throughput

0.458

High

1316461

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

1347460

CEP76
Centrosomal protein of 76 kDa

1

0

High-throughput

0.458

High

1359542

CKAP2
Cytoskeleton-associated protein 2

1

0

High-throughput

0.458

High

1363982

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1371969

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

0

High-throughput

0.458

High

1394986

VCIP1
Deubiquitinating protein VCPIP1

1

0

High-throughput

0.458

High

1399500

IPO9
Importin-9

1

0

High-throughput

0.458

High

1405215

MPP9
M-phase phosphoprotein 9

1

0

High-throughput

0.458

High

1407818

HAUS7
HAUS augmin-like complex subunit 7

1

0

High-throughput

0.458

High

1413076

HAUS8
HAUS augmin-like complex subunit 8

1

0

High-throughput

0.458

High

1415758

TALD3
Protein TALPID3

1

0

High-throughput

0.458

High

1429661

COMD4
COMM domain-containing protein 4

1

0

High-throughput

0.458

High

1432858

CENPH
Centromere protein H

1

0

High-throughput

0.458

High

1436879

CNO10
CCR4-NOT transcription complex subunit 10

1

0

High-throughput

0.458

High

1438723

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.458

High

1438729

ATX10
Ataxin-10

1

0

High-throughput

0.458

High

1433311

WNK1
Serine/threonine-protein kinase WNK1

1

7

High-throughput

0.457

High

1438735

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.457

High

1428367

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

8

High-throughput

0.445

High

1438725

PLK2
Serine/threonine-protein kinase PLK2

1

6

Small-scale

0.445

High

126189

AP3B1
AP-3 complex subunit beta-1

1

4

High-throughput

0.437

High

158889

AP3D1
AP-3 complex subunit delta-1

1

4

High-throughput

0.437

High

299381

FLOT1
Flotillin-1

1

4

High-throughput

0.437

High

829161

RFC5
Replication factor C subunit 5

1

1

High-throughput

0.437

High

936530

AF10
Protein AF-10

1

1

High-throughput

0.437

High

1155792

EZH2
Histone-lysine N-methyltransferase EZH2

1

8

High-throughput

0.437

High

1351051

DDX54
ATP-dependent RNA helicase DDX54

1

5

High-throughput

0.437

High

1411665

GPTC1
G patch domain-containing protein 1

1

3

High-throughput

0.437

High

1438742

AAR2
Protein AAR2 homolog

1

3

High-throughput

0.437

High

914758

RM12
Large ribosomal subunit protein bL12m

2

0

High-throughput

0.328

High

1438720

Q9HCK3
KIAA1569 protein

2

0

High-throughput

0.305

High

641318

SIAL
Integrin-binding sialoprotein

1

0

High-throughput

0.279

Low

1009326

PRR3
Proline-rich protein 3

1

0

High-throughput

0.279

Low

1108487

NAB1
NGFI-A-binding protein 1

1

0

High-throughput

0.279

Low

66668

CC85C
Coiled-coil domain-containing protein 85C

1

0

High-throughput

0.249

Low

1314638

M21D2
Nucleotidyltransferase MB21D2

1

0

High-throughput

0.249

Low

1397840

CC138
Coiled-coil domain-containing protein 138

1

0

High-throughput

0.249

Low

1417926

K1671
Uncharacterized protein KIAA1671

1

0

High-throughput

0.249

Low

1436869

ARMT1
Damage-control phosphatase ARMT1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025