Interactor 1: HRK (O00198)
Activator of apoptosis harakiri (BH3-interacting domain-containing protein 3) (Neuronal death protein DP5)
Gene: HRK
Interactor 2: B2CL1 (Q07817)
Bcl-2-like protein 1 (Bcl2-L-1) (Apoptosis regulator Bcl-X)
Gene: BCL2L1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.92 | 0.60 | 0.746 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 9130713, 10075695, 15721256, 16697956, 14596824, 15031724, 15694340 |
| Identification Methods | two hybrid, affinity chromatography technology, unspecified method, fluorescent resonance energy transfer, fluorescence polarization spectroscopy, scintillation proximity assay, surface plasmon resonance |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005739 - mitochondrion GO:0043065 - positive regulation of apoptotic process |
| Homologous interactions | 4 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
