Protein: B2CL2
Bcl-2-like protein 2 (Bcl2-L-2) (Apoptosis regulator Bcl-W)

Gene: B2CL2, BCL2L2
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q92843

Gene Ontology (top 5):
GO:0001836 - release of cytochrome c from mitochondria
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol
GO:0007283 - spermatogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

219650

B2L11
Bcl-2-like protein 11

11

17

Small-scale

0.977

High

1060113

BAX
Apoptosis regulator BAX

8

17

Small-scale

0.968

High

1369440

BAD
Bcl2-associated agonist of cell death

9

8

Small-scale

0.968

High

939640

BID
BH3-interacting domain death agonist

5

10

Small-scale

0.931

High

1159451

BAK
Bcl-2 homologous antagonist/killer

5

17

Small-scale

0.927

High

1369444

BMF
Bcl-2-modifying factor

4

8

Small-scale

0.903

High

1369449

BBC3
Bcl-2-binding component 3, isoforms 1/2

4

7

Small-scale

0.873

High

1115575

ASPP2
Apoptosis-stimulating of p53 protein 2

2

3

Small-scale

0.799

High

414337

P53
Cellular tumor antigen p53

2

9

Small-scale

0.792

High

1102429

BIK
Bcl-2-interacting killer

8

6

Small-scale

0.754

High

1369438

B2CL2
Bcl-2-like protein 2

1

18

Small-scale

0.716

High

1329419

KASH5
Protein KASH5

4

1

High-throughput

0.707

High

505105

BNIP5
Protein BNIP5

2

2

High-throughput

0.700

High

1228808

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

2

2

High-throughput

0.700

High

1117290

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

7

Small-scale

0.692

High

1369441

FATE1
Fetal and adult testis-expressed transcript protein

3

0

High-throughput

0.646

High

242481

PRKN
E3 ubiquitin-protein ligase parkin

1

7

Small-scale

0.618

High

1369445

BBC3B
Bcl-2-binding component 3, isoforms 3/4

2

5

High-throughput

0.611

High

692475

G0S2
G0/G1 switch protein 2

2

1

High-throughput

0.606

High

1214414

GORAB
RAB6-interacting golgin

2

1

High-throughput

0.606

High

1315184

CJ067
Uncharacterized protein C10orf67, mitochondrial

2

1

High-throughput

0.606

High

1327913

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

1

High-throughput

0.606

High

1369455

SAR1A
Small COPII coat GTPase SAR1A

2

1

High-throughput

0.606

High

1369456

CIDEB
Lipid transferase CIDEB

2

1

High-throughput

0.606

High

171542

S27A2
Long-chain fatty acid transport protein 2

2

0

High-throughput

0.602

High

337787

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.580

High

617561

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

2

0

High-throughput

0.580

High

690329

STOM
Stomatin

2

0

High-throughput

0.580

High

1369452

CHODL
Chondrolectin

2

0

High-throughput

0.580

High

967895

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

11

Small-scale

0.561

High

407676

S100B
Protein S100-B

1

1

High-throughput

0.560

High

590325

MUC1
Mucin-1

2

1

High-throughput

0.553

High

1105229

S39A6
Zinc transporter ZIP6

2

1

High-throughput

0.553

High

1238174

RHBD2
Rhomboid domain-containing protein 2

2

1

High-throughput

0.553

High

1369448

MGST2
Microsomal glutathione S-transferase 2

2

1

High-throughput

0.553

High

1369451

TMX1
Thioredoxin-related transmembrane protein 1

2

1

High-throughput

0.553

High

1369453

S39A2
Zinc transporter ZIP2

2

1

High-throughput

0.553

High

1369454

S35C2
Solute carrier family 35 member C2

2

1

High-throughput

0.553

High

1314979

TEX11
Testis-expressed protein 11

1

0

High-throughput

0.536

High

1115874

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

9

High-throughput

0.536

High

1272085

BOP
Protein Bop

1

6

Small-scale

0.515

High

192618

NUP42
Nucleoporin NUP42

1

0

High-throughput

0.513

High

1102043

PABP4
Polyadenylate-binding protein 4

1

0

High-throughput

0.513

High

1233203

THOC7
THO complex subunit 7

1

0

High-throughput

0.513

High

1369446

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

0

High-throughput

0.513

High

578525

BRAF
Serine/threonine-protein kinase B-raf

1

3

High-throughput

0.506

High

126020

HRK
Activator of apoptosis harakiri

1

4

Small-scale

0.501

High

1109188

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

7

High-throughput

0.489

High

1092071

BNIP3
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3

1

5

High-throughput

0.481

High

970869

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

1093391

TRI32
E3 ubiquitin-protein ligase TRIM32

1

6

Small-scale

0.479

High

1369450

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

8

Small-scale

0.479

High

1369457

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

1

High-throughput

0.470

High

386047

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

106394

APRIO
Alternative prion protein

1

0

High-throughput

0.458

High

1104628

IKZF1
DNA-binding protein Ikaros

1

1

High-throughput

0.457

High

698336

MAP4
Microtubule-associated protein 4

1

2

High-throughput

0.445

High

1340990

THOC2
THO complex subunit 2

1

1

High-throughput

0.437

High

952283

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

0

High-throughput

0.426

High

1337620

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.426

High

478142

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.407

High

775239

FUS
RNA-binding protein FUS

1

1

High-throughput

0.407

High

887075

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.373

High

549845

CD79A
B-cell antigen receptor complex-associated protein alpha chain

3

0

High-throughput

0.337

High

337897

CLD7
Claudin-7

2

0

High-throughput

0.316

High

387595

APOC1
Apolipoprotein C-I

2

0

High-throughput

0.316

High

870062

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

933981

APOC4
Apolipoprotein C-IV

2

0

High-throughput

0.316

High

951946

SYCY2
Syncytin-2

2

0

High-throughput

0.316

High

1274012

BHA09
Class A basic helix-loop-helix protein 9

2

0

High-throughput

0.316

High

1280800

S35E3
Solute carrier family 35 member E3

2

0

High-throughput

0.316

High

1308341

TM139
Transmembrane protein 139

2

0

High-throughput

0.316

High

1351756

GP151
G-protein coupled receptor 151

2

0

High-throughput

0.316

High

1352479

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.316

High

1369443

SUSD3
Sushi domain-containing protein 3

2

0

High-throughput

0.316

High

1369447

PANX1
Pannexin-1

2

0

High-throughput

0.316

High

587165

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

1256709

NKAP1
Uncharacterized protein NKAPD1

1

0

High-throughput

0.279

Low

1278298

LRP10
Low-density lipoprotein receptor-related protein 10

1

0

High-throughput

0.268

Low

1281749

T179B
Transmembrane protein 179B

1

0

High-throughput

0.268

Low

1369439

FGF14
Fibroblast growth factor 14

1

0

High-throughput

0.268

Low

387629

APOC2
Apolipoprotein C-II

1

0

High-throughput

0.251

Low

1369442

LRIQ1
Leucine-rich repeat- and IQ domain-containing protein 1

1

0

High-throughput

0.251

Low

556263

CADH1
Cadherin-1

1

0

High-throughput

0.249

Low

480251

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.232

Low

542146

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.232

Low

1119236

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.232

Low

1231274

BLT3A
Bridge-like lipid transfer protein family member 3A

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025