Protein: ETS1
Protein C-ets-1 (p54)

Gene: ETS1
Organism: Homo sapiens
Interactions: 157
UniProt ID: P14921

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001222 - transcription corepressor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

542053

CBP
CREB-binding protein

5

20

Small-scale

0.716

High

386024

P53
Cellular tumor antigen p53

4

5

Small-scale

0.676

High

541970

ETS2
Protein C-ets-2

1

18

Small-scale

0.647

High

541977

SPI1
Transcription factor PU.1

1

18

Small-scale

0.647

High

541969

ETS1
Protein C-ets-1

1

18

High-throughput

0.646

High

542000

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

9

Small-scale

0.646

High

401351

JUN
Transcription factor Jun

2

17

Small-scale

0.639

High

542080

DAXX
Death domain-associated protein 6

3

0

Small-scale

0.630

High

316301

TYDP2
Tyrosyl-DNA phosphodiesterase 2

2

1

Small-scale

0.628

High

317897

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

14

Small-scale

0.618

High

541979

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

9

High-throughput

0.618

High

542012

PEBB
Core-binding factor subunit beta

1

1

High-throughput

0.618

High

542003

SRS11
Serine/arginine-rich splicing factor 11

2

2

High-throughput

0.614

High

541974

CREB1
Cyclic AMP-responsive element-binding protein 1

2

4

Small-scale

0.595

High

542044

COP1
E3 ubiquitin-protein ligase COP1

1

15

Small-scale

0.589

High

455047

PARP1
Poly [ADP-ribose] polymerase 1

2

4

Small-scale

0.585

High

523492

XRCC6
X-ray repair cross-complementing protein 6

2

12

Small-scale

0.585

High

541992

SMCA2
Probable global transcription activator SNF2L2

2

17

High-throughput

0.584

High

542039

PIAS4
E3 SUMO-protein ligase PIAS4

2

14

Small-scale

0.584

High

542019

ARI4B
AT-rich interactive domain-containing protein 4B

1

20

High-throughput

0.578

High

542006

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.571

High

541978

NUCL
Nucleolin

1

2

High-throughput

0.561

High

542005

APLP2
Amyloid beta precursor like protein 2

1

12

High-throughput

0.561

High

542010

MK07
Mitogen-activated protein kinase 7

1

19

Small-scale

0.561

High

242665

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.554

High

541998

PRKDC
DNA-dependent protein kinase catalytic subunit

1

8

Small-scale

0.550

High

541988

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.537

High

542023

AR6P4
ADP-ribosylation factor-like protein 6-interacting protein 4

1

0

High-throughput

0.537

High

541982

SP100
Nuclear autoantigen Sp-100

1

17

Small-scale

0.529

High

541997

UBC9
SUMO-conjugating enzyme UBC9

1

9

Small-scale

0.527

High

129964

MEIS1
Homeobox protein Meis1

1

2

Small-scale

0.515

High

167460

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

3

Small-scale

0.515

High

542073

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

3

High-throughput

0.515

High

541980

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

0

High-throughput

0.513

High

542078

THUM1
THUMP domain-containing protein 1

1

0

High-throughput

0.513

High

394051

A4
Amyloid-beta precursor protein

1

12

High-throughput

0.501

High

434920

SP1
Transcription factor Sp1

1

20

Small-scale

0.501

High

522743

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

Small-scale

0.501

High

541971

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

12

Small-scale

0.501

High

541981

TBP
TATA-box-binding protein

1

3

Small-scale

0.501

High

541983

PIT1
Pituitary-specific positive transcription factor 1

1

9

Small-scale

0.501

High

541987

BRCA1
Breast cancer type 1 susceptibility protein

1

7

Small-scale

0.501

High

542004

MTG8
Protein CBFA2T1

1

2

Small-scale

0.501

High

542007

FOXO1
Forkhead box protein O1

1

17

Small-scale

0.501

High

542011

RUNX2
Runt-related transcription factor 2

1

4

Small-scale

0.501

High

542074

SRA1
Steroid receptor RNA activator 1

1

1

Small-scale

0.501

High

541976

TAL1
T-cell acute lymphocytic leukemia protein 1

1

15

Small-scale

0.500

High

542034

RBBP6
E3 ubiquitin-protein ligase RBBP6

1

6

Small-scale

0.481

High

265107

MAF
Transcription factor Maf

1

0

Small-scale

0.480

High

542083

DNM3L
DNA

1

0

Small-scale

0.480

High

146151

ARI1A
AT-rich interactive domain-containing protein 1A

1

19

High-throughput

0.479

High

152583

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

170240

TIF1A
Transcription intermediary factor 1-alpha

1

20

High-throughput

0.479

High

183059

KDM6A
Lysine-specific demethylase 6A

1

7

High-throughput

0.479

High

211790

TLX3
T-cell leukemia homeobox protein 3

1

13

Small-scale

0.479

High

257447

CREST
Calcium-responsive transactivator

1

20

High-throughput

0.479

High

261392

NCOR1
Nuclear receptor corepressor 1

1

18

Small-scale

0.479

High

296638

SLIT2
Slit homolog 2 protein

1

1

High-throughput

0.479

High

299034

PHF14
PHD finger protein 14

1

4

High-throughput

0.479

High

312012

ZBT7A
Zinc finger and BTB domain-containing protein 7A

1

7

Small-scale

0.479

High

388196

HSPB1
Heat shock protein beta-1

1

4

Small-scale

0.479

High

422341

NFM
Neurofilament medium polypeptide

1

2

High-throughput

0.479

High

422481

CENPB
Major centromere autoantigen B

1

5

High-throughput

0.479

High

430855

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.479

High

439262

MMP3
Stromelysin-1

1

1

Small-scale

0.479

High

449519

HMGB1
High mobility group protein B1

1

20

High-throughput

0.479

High

541972

ZEP1
Zinc finger protein 40

1

6

High-throughput

0.479

High

541975

JUND
Transcription factor JunD

1

15

High-throughput

0.479

High

541985

TLX1
T-cell leukemia homeobox protein 1

1

17

Small-scale

0.479

High

541989

SYAC
Alanine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

541990

CEBPA
CCAAT/enhancer-binding protein alpha

1

9

High-throughput

0.479

High

541991

TAF6
Transcription initiation factor TFIID subunit 6

1

5

High-throughput

0.479

High

541993

SMCA4
Transcription activator BRG1

1

18

High-throughput

0.479

High

541994

TTC3
E3 ubiquitin-protein ligase TTC3

1

3

High-throughput

0.479

High

542001

SET
Protein SET

1

1

High-throughput

0.479

High

542002

TLE3
Transducin-like enhancer protein 3

1

16

High-throughput

0.479

High

542008

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

3

High-throughput

0.479

High

542009

BPTF
Nucleosome-remodeling factor subunit BPTF

1

20

High-throughput

0.479

High

542013

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

High-throughput

0.479

High

542014

PLEC
Plectin

1

1

Small-scale

0.479

High

542016

NCOA1
Nuclear receptor coactivator 1

1

19

Small-scale

0.479

High

542020

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

7

High-throughput

0.479

High

542024

ARID2
AT-rich interactive domain-containing protein 2

1

20

High-throughput

0.479

High

542025

ELP2
Elongator complex protein 2

1

2

High-throughput

0.479

High

542026

NFRKB
Nuclear factor related to kappa-B-binding protein

1

13

High-throughput

0.479

High

542028

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

12

High-throughput

0.479

High

542029

SRCAP
Helicase SRCAP

1

20

High-throughput

0.479

High

542030

UBN2
Ubinuclein-2

1

19

High-throughput

0.479

High

542031

PAXI1
PAX-interacting protein 1

1

12

High-throughput

0.479

High

542033

EMSY
BRCA2-interacting transcriptional repressor EMSY

1

20

High-throughput

0.479

High

542035

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

4

Small-scale

0.479

High

542036

PB1
Protein polybromo-1

1

20

High-throughput

0.479

High

542037

MGAP
MAX gene-associated protein

1

6

High-throughput

0.479

High

542042

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

542043

KDM2B
Lysine-specific demethylase 2B

1

16

High-throughput

0.479

High

542045

SMRC2
SWI/SNF complex subunit SMARCC2

1

20

High-throughput

0.479

High

542046

PHF10
PHD finger protein 10

1

20

High-throughput

0.479

High

542047

GATD1
GATA zinc finger domain-containing protein 1

1

4

High-throughput

0.479

High

542048

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

7

High-throughput

0.479

High

542049

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

7

High-throughput

0.479

High

542050

TSC1
Hamartin

1

4

High-throughput

0.479

High

542051

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

542052

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

542054

KAT2B
Histone acetyltransferase KAT2B

1

20

Small-scale

0.479

High

542055

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

High-throughput

0.479

High

542056

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

18

High-throughput

0.479

High

542058

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

12

High-throughput

0.479

High

542060

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

12

High-throughput

0.479

High

542061

ZFR
Zinc finger RNA-binding protein

1

2

High-throughput

0.479

High

542062

EP400
E1A-binding protein p400

1

20

High-throughput

0.479

High

542064

PHF12
PHD finger protein 12

1

20

High-throughput

0.479

High

542067

CDC5L
Cell division cycle 5-like protein

1

6

High-throughput

0.479

High

542068

PFD5
Prefoldin subunit 5

1

1

High-throughput

0.479

High

542070

EPAS1
Endothelial PAS domain-containing protein 1

1

17

Small-scale

0.479

High

542075

BRD7
Bromodomain-containing protein 7

1

20

High-throughput

0.479

High

542081

TRPS1
Zinc finger transcription factor Trps1

1

10

High-throughput

0.479

High

542087

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

14

Small-scale

0.479

High

542089

LAS1L
Ribosomal biogenesis protein LAS1L

1

1

High-throughput

0.479

High

542090

PPME1
Protein phosphatase methylesterase 1

1

1

High-throughput

0.479

High

542091

NCOA3
Nuclear receptor coactivator 3

1

19

Small-scale

0.479

High

352471

TNFA
Tumor necrosis factor

1

0

Small-scale

0.458

High

537785

KPYM
Pyruvate kinase PKM

1

0

High-throughput

0.458

High

541995

RD23B
UV excision repair protein RAD23 homolog B

1

0

High-throughput

0.458

High

541996

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

Small-scale

0.458

High

542027

CPLX2
Complexin-2

1

0

High-throughput

0.458

High

542040

CA052
UPF0690 protein C1orf52

1

0

High-throughput

0.458

High

542041

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

542057

TCAL3
Transcription elongation factor A protein-like 3

1

0

High-throughput

0.458

High

542059

DYL2
Dynein light chain 2, cytoplasmic

1

0

High-throughput

0.458

High

542063

ZMAT2
Zinc finger matrin-type protein 2

1

0

High-throughput

0.458

High

542072

CHM4A
Charged multivesicular body protein 4a

1

0

High-throughput

0.458

High

542076

MBIP1
MAP3K12-binding inhibitory protein 1

1

0

High-throughput

0.458

High

542077

BCD1
Box C/D snoRNA protein 1

1

0

High-throughput

0.458

High

542082

SCOC
Short coiled-coil protein

1

0

High-throughput

0.458

High

542079

GGA3
ADP-ribosylation factor-binding protein GGA3

1

2

High-throughput

0.457

High

542084

GGA2
ADP-ribosylation factor-binding protein GGA2

1

2

High-throughput

0.457

High

524778

XRCC5
X-ray repair cross-complementing protein 5

1

12

Small-scale

0.445

High

541973

ITF2
Transcription factor 4

1

2

Small-scale

0.445

High

541984

MK01
Mitogen-activated protein kinase 1

1

19

Small-scale

0.445

High

541986

CTNB1
Catenin beta-1

1

3

Small-scale

0.445

High

542017

MK14
Mitogen-activated protein kinase 14

1

20

Small-scale

0.445

High

541999

ALEX
Protein ALEX

1

8

High-throughput

0.437

High

542018

CP51A
Lanosterol 14-alpha demethylase

1

1

High-throughput

0.437

High

542032

SV2A
Synaptic vesicle glycoprotein 2A

1

1

High-throughput

0.437

High

542038

WDR17
WD repeat-containing protein 17

1

10

High-throughput

0.437

High

542065

PCX1
Pecanex-like protein 1

1

20

High-throughput

0.437

High

542066

KS6C1
Ribosomal protein S6 kinase delta-1

1

2

High-throughput

0.437

High

542069

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

2

Small-scale

0.437

High

542086

ACAD8
Isobutyryl-CoA dehydrogenase, mitochondrial

1

1

High-throughput

0.437

High

542085

GGA1
ADP-ribosylation factor-binding protein GGA1

1

2

High-throughput

0.408

High

542088

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

Small-scale

0.408

High

542071

CYBC1
Cytochrome b-245 chaperone 1

1

0

High-throughput

0.301

High

542015

CH3L2
Chitinase-3-like protein 2

1

0

High-throughput

0.279

Low

176712

EIF3D
Eukaryotic translation initiation factor 3 subunit D

1

0

High-throughput

0.249

Low

542021

NOMO2
BOS complex subunit NOMO2

1

0

High-throughput

0.249

Low

542022

F1711
Protein FAM171A1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024