HitPredict

Interactor 1: ZNRF4 (Q8WWF5)
E3 ubiquitin-protein ligase ZNRF4 (EC 2.3.2.27) (Nixin) (RING finger protein 204) (RING-type E3 ubiquitin transferase ZNRF4) (Zinc/RING finger protein 4)
Gene: ZNRF4

Interactor 2: TYW1 (Q9NV66)
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1 (EC 4.1.3.44) (Radical S-adenosyl methionine and flavodoxin domain-containing protein 1) (tRNA wybutosine-synthesizing protein 1 homolog) (tRNA-yW-synthesizing protein)
Gene: TYW1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 429 Hs			1 732
+	Hs
		560225 RN149_HUMAN (95-390): 4.12e-66: 218: 18.61		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		560218 GOLI_HUMAN (118-429): 2.7e-64: 214: 19.58		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04
+	Hs
		560213 SYVN1_HUMAN (143-374): 3.91e-31: 127: 13.93		NCPR_HUMAN (1-353): 3.38e-86: 287: 22.04