Protein: ATC3
Phospholipid-transporting ATPase DRS2 (EC 7.6.2.1)

Gene: ATC3, DRS2
Organism: Saccharomyces cerevisiae S288C
Interactions: 70
UniProt ID: P39524

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0005802 - trans-Golgi network
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

679022

CDC50
Phospholipid-transporting ATPase accessory subunit CDC50

11

20

Small-scale

0.981

High

812281

LEM3
Phospholipid-transporting ATPase accessory subunit LEM3

4

20

Small-scale

0.887

High

744383

ATC5
Phospholipid-transporting ATPase DNF1

2

16

High-throughput

0.793

High

812276

FLC2
Flavin carrier protein 2

3

1

High-throughput

0.643

High

812274

RCY1
Recyclin-1

2

2

Small-scale

0.631

High

812273

ATC3
Phospholipid-transporting ATPase DRS2

1

12

Small-scale

0.618

High

812304

ATC4
Phospholipid-transporting ATPase DNF2

1

13

High-throughput

0.618

High

484297

KEX1
Pheromone-processing carboxypeptidase KEX1

2

2

High-throughput

0.614

High

712791

CHS3
Chitin synthase 3

2

2

High-throughput

0.614

High

812301

ATG9
Autophagy-related protein 9

2

4

Small-scale

0.586

High

793647

ARL1
ADP-ribosylation factor-like protein 1

1

3

Small-scale

0.573

High

812277

GEA2
ARF guanine-nucleotide exchange factor 2

2

2

Small-scale

0.566

High

720836

ITR1
Myo-inositol transporter 1

1

5

Small-scale

0.552

High

735833

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

1

Small-scale

0.552

High

812293

TCB3
Tricalbin-3

1

2

Small-scale

0.552

High

812299

PIN2
[PSI+] induction protein 2

1

1

High-throughput

0.541

High

726042

FUN30
ATP-dependent helicase FUN30

1

1

High-throughput

0.515

High

812303

OSH2
Oxysterol-binding protein homolog 2

1

1

High-throughput

0.515

High

740262

SMI1
Cell wall assembly regulator SMI1

1

1

High-throughput

0.494

High

574800

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

1

0

High-throughput

0.493

High

582469

SEC23
Protein transport protein SEC23

1

3

High-throughput

0.479

High

597140

BIP
Endoplasmic reticulum chaperone BiP

1

4

Small-scale

0.479

High

663315

FPS1
Glycerol uptake/efflux facilitator protein

1

7

High-throughput

0.479

High

739964

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

1

2

Small-scale

0.479

High

751580

SNC2
Synaptobrevin homolog 2

1

7

High-throughput

0.479

High

778844

AP1B1
AP-1 complex subunit beta-1

1

2

Small-scale

0.479

High

780751

PSG1
PMA1 stabilization in the Golgi protein 1 [Cleaved into: PSG1-N'; PSG1-C']

1

1

High-throughput

0.479

High

788444

GEF1
Anion/proton exchange transporter GEF1

1

1

High-throughput

0.479

High

790322

VPP2
V-type proton ATPase subunit a, Golgi isoform

1

4

High-throughput

0.479

High

801998

MSC7
Putative aldehyde dehydrogenase-like protein YHR039C

1

1

High-throughput

0.479

High

812275

PHO90
Low-affinity phosphate transporter PHO90

1

2

High-throughput

0.479

High

812285

CCH1
Calcium-channel protein CCH1

1

7

High-throughput

0.479

High

812287

AIM14
Probable metalloreductase AIM14

1

2

High-throughput

0.479

High

812289

ARE2
Sterol O-acyltransferase 2

1

1

High-throughput

0.479

High

812302

TPO4
Polyamine transporter 4

1

3

High-throughput

0.479

High

750189

UFD4
Ubiquitin fusion degradation protein 4

1

4

High-throughput

0.470

High

812278

VTC1
Vacuolar transporter chaperone complex subunit 1

1

0

High-throughput

0.458

High

812291

YNJ5
Uncharacterized transporter YNL095C

1

0

High-throughput

0.458

High

812297

YL413
Cell membrane protein YLR413W

1

0

High-throughput

0.458

High

536025

SEC7
ADP-ribosylation factor guanine nucleotide-exchange factor SEC7

1

2

High-throughput

0.457

High

392748

HSP82
ATP-dependent molecular chaperone HSP82

1

4

High-throughput

0.445

High

741601

HSP7F
Heat shock protein homolog SSE1

1

5

High-throughput

0.445

High

636664

PSA1
Proteasome subunit alpha type-1

1

3

High-throughput

0.437

High

661517

PSA2
Proteasome subunit alpha type-2

1

3

High-throughput

0.437

High

707131

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

746240

PTM1
Membrane protein PTM1

1

3

High-throughput

0.437

High

795352

ATG8
Autophagy-related protein 8

1

5

High-throughput

0.437

High

800843

PSB1
Proteasome subunit beta type-1

1

4

High-throughput

0.437

High

803242

YHB7
Uncharacterized membrane protein YHL071W

1

3

High-throughput

0.437

High

812292

APJ1
J domain-containing protein APJ1

1

3

High-throughput

0.437

High

812295

TVP18
Golgi apparatus membrane protein TVP18

1

1

High-throughput

0.437

High

812296

ATG23
Autophagy-related protein 23

1

3

High-throughput

0.437

High

812298

AP1G1
AP-1 complex subunit gamma-1

1

1

Small-scale

0.437

High

550761

INO1
Inositol-3-phosphate synthase

1

0

Small-scale

0.288

High

812282

VNX1
Low affinity vacuolar monovalent cation/H(+) antiporter

1

0

Small-scale

0.288

High

735721

VA0D
V-type proton ATPase subunit d

1

0

High-throughput

0.269

Low

812294

POB3
FACT complex subunit POB3

1

0

High-throughput

0.269

Low

812284

SCD6
Protein SCD6

1

0

Small-scale

0.251

Low

528821

RLA3
Large ribosomal subunit protein P1B

1

0

High-throughput

0.249

Low

664293

SSD1
Protein SSD1

1

0

Small-scale

0.249

Low

738533

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.249

Low

779840

YO062
Uncharacterized protein YOR062C

1

0

High-throughput

0.249

Low

812279

PRM2
Pheromone-regulated membrane protein 2

1

0

High-throughput

0.249

Low

812280

COPB
Coatomer subunit beta

1

0

Small-scale

0.249

Low

812283

MHP1
MAP-homologous protein 1

1

0

Small-scale

0.249

Low

812286

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.249

Low

812288

YG36
Uncharacterized protein YGR126W

1

0

High-throughput

0.249

Low

812290

YNL5
Uncharacterized vacuolar membrane protein YNL115C

1

0

High-throughput

0.249

Low

812300

NOP53
Ribosome biogenesis protein NOP53

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025