Interactor 1: NALP7 (Q8WX94)
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)
Gene: NLRP7

Interactor 2: NALP7 (Q8WX94)
NACHT, LRR and PYD domains-containing protein 7 (Nucleotide-binding oligomerization domain protein 12) (PYRIN-containing APAF1-like protein 3)
Gene: NLRP7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.42 1.00 0.653

The method score is based on:

Property Details
Experiments 25082979
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_6~LRR_6, NACHT~NACHT, NACHT~NLRC4_HD2, NACHT~NOD2_WH, NLRC4_HD2~NOD2_WH, PYRIN~PYRIN
Common GO terms GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0010955 - negative regulation of protein processing
GO:0019828 - aspartic-type endopeptidase inhibitor activity
GO:0019966 - interleukin-1 binding
and 6 others

more...

Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 980
Hs

1 980
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ At
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024