HitPredict

Interactor 1: JDP2 (Q8WYK2)
Jun dimerization protein 2
Gene: JDP2

Interactor 2: HDA10 (Q969S8)
Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10)
Gene: HDAC10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22989952
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0042826 - histone deacetylase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 163 Hs			1 669
+	Hs
		579223 ATF3_HUMAN (3-162): 1.97e-20: 84.5: 45.61		HDA10_HUMAN (1-669): 0: 866: 100.00
+	Hs
		1038579 JDP2_HUMAN (1-163): 8.09e-33: 116: 100.00		HDAC1_HUMAN (6-449): 1.69e-153: 454: 20.09
+	Mm
		140255 JDP2_MOUSE (1-163): 9.02e-33: 115: 96.32		HDAC1_MOUSE (6-449): 4.86e-154: 455: 20.09
+	Mm
		936382 JDP2_MOUSE (1-163): 9.02e-33: 115: 96.32		HDAC2_MOUSE (6-457): 1.39e-151: 449: 19.96
+	Hs
		1264525 JDP2_HUMAN (1-163): 8.09e-33: 116: 100.00		HDAC6_HUMAN (3-409): 1.45e-141: 445: 47.55
+	Mm
		140216 JUNB_MOUSE (7-135): 5.35e-24: 97.2: 23.13		HDAC1_MOUSE (6-449): 4.86e-154: 455: 20.09
+	Mm
		450547 JUNB_MOUSE (7-135): 5.35e-24: 97.2: 23.13		HDAC2_MOUSE (6-457): 1.39e-151: 449: 19.96
+	Dm
		599218 FOSLA_DROME (18-159): 2.54e-25: 102: 27.27		HDAC1_DROME (6-459): 2.75e-149: 444: 18.78
+	Mm
		936396 ATF3_MOUSE (3-162): 2.41e-24: 94.9: 44.44		HDAC2_MOUSE (6-457): 1.39e-151: 449: 19.96
+	Hs
		548245 FOSL1_HUMAN (29-162): 3.92e-21: 88.4: 32.84		HDAC1_HUMAN (6-449): 1.69e-153: 454: 20.09
+	Hs
		345504 FOS_HUMAN (19-163): 1.76e-21: 91.1: 31.14		HDAC2_HUMAN (6-457): 3.88e-152: 451: 19.96
+	Hs
		579204 ATF3_HUMAN (3-162): 1.97e-20: 84.5: 45.61		HDAC1_HUMAN (6-449): 1.69e-153: 454: 20.09
+	Mm
		526735 FOSB_MOUSE (82-150): 5.11e-19: 83.7: 40.58		HDAC2_MOUSE (6-457): 1.39e-151: 449: 19.96
+	Hs
		579232 ATF3_HUMAN (3-162): 1.97e-20: 84.5: 45.61		HDAC6_HUMAN (3-409): 1.45e-141: 445: 47.55
+	Sp
		857023 ATF1_SCHPO (2-151): 1.51e-25: 103: 19.48		CLR3_SCHPO (321-662): 6.79e-33: 136: 16.82
+	Hs
		1264526 JDP2_HUMAN (1-163): 8.09e-33: 116: 100.00		HDAC5_HUMAN (434-663): 1.83e-25: 114: 19.79
+	Hs
		880797 JDP2_HUMAN (1-163): 8.09e-33: 116: 100.00		HDAC4_HUMAN (434-663): 6.76e-24: 109: 18.38
+	Hs
		547761 ATF2_HUMAN (6-148): 1.25e-21: 92.2: 21.68		HDAC4_HUMAN (434-663): 6.76e-24: 109: 18.38
+	Hs
		579236 ATF3_HUMAN (3-162): 1.97e-20: 84.5: 45.61		HDAC5_HUMAN (434-663): 1.83e-25: 114: 19.79
+	Hs
		579186 ATF3_HUMAN (3-162): 1.97e-20: 84.5: 45.61		HDAC4_HUMAN (434-663): 6.76e-24: 109: 18.38