HitPredict

Interactor 1: TSC1 (Q92574)
Hamartin (Tuberous sclerosis 1 protein)
Gene: TSC1

Interactor 2: TF7L2 (Q9NQB0)
Transcription factor 7-like 2 (HMG box transcription factor 4) (T-cell-specific transcription factor 4) (T-cell factor 4) (TCF-4) (hTCF-4)
Gene: TCF7L2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1164 Hs			1 619
+	Hs
		989542 TSC1_HUMAN (1-1164): 0: 725: 100.00		SOX4_HUMAN (349-420): 8.6e-16: 82.5: 33.33
+	Hs
		1203638 Q86WV8_HUMAN (1-343): 3.4e-177: 526: 100.00		TF7L2_HUMAN (1-619): 4e-84: 277: 100.00
+	Hs
		551812 DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54		CIC_HUMAN (43-578): 1.85e-33: 139: 15.01
+	Hs
		148725 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		SSRP1_HUMAN (333-511): 2.38e-26: 116: 18.89
+	Hs
		148522 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		551635 DESP_HUMAN (570-1151): 1.05e-21: 104: 11.54		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		818141 MRCKA_HUMAN (278-842): 4.78e-17: 89.1: 8.78		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		818194 MYH14_HUMAN (620-918): 1.78e-11: 71.1: 13.11		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		725110 MYH10_HUMAN (687-992): 3.26e-09: 63.6: 20.43		SOX2_HUMAN (316-613): 5.49e-27: 113: 15.69
+	Hs
		149481 CTRO_HUMAN (337-991): 3.67e-23: 109: 7.78		PCLO_HUMAN (20-610): 1.45e-09: 63.4: 9.22