HitPredict

Interactor 1: HS105 (Q92598)
Heat shock protein 105 kDa (Antigen NY-CO-25) (Heat shock 110 kDa protein) (Heat shock protein family H member 1)
Gene: HSPH1

Interactor 2: DNJC7 (Q99615)
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
Gene: DNAJC7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DnaJ~HSP70
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006457 - protein folding GO:0051085 - chaperone cofactor-dependent protein refolding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 858 Hs			1 494
+	Hs
		320902 HS74L_HUMAN (1-858): 0: 953: 57.46		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		714375 HSP74_HUMAN (1-858): 0: 917: 60.98		DNJC7_HUMAN (1-494): 2.58e-85: 273: 100.00
+	Hs
		684925 HS105_HUMAN (1-858): 0: 1004: 100.00		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279330 HS105_HUMAN (1-858): 0: 1004: 100.00		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		1267773 HS105_HUMAN (1-858): 0: 1004: 100.00		DNJB4_HUMAN (380-479): 7.53e-18: 86.7: 45.22
+	Hs
		1123860 HS105_HUMAN (1-858): 0: 1004: 100.00		Q59E89_HUMAN (380-479): 1.44e-17: 85.9: 45.22
+	Hs
		320819 HS74L_HUMAN (1-858): 0: 953: 57.46		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		714208 HSP74_HUMAN (1-858): 0: 917: 60.98		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		684440 HSP74_HUMAN (1-858): 0: 917: 60.98		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Hs
		279281 HSP74_HUMAN (1-858): 0: 917: 60.98		DNJB5_HUMAN (380-491): 5.82e-19: 90.1: 43.31
+	Hs
		714449 HSP74_HUMAN (1-858): 0: 917: 60.98		DNJB4_HUMAN (380-479): 7.53e-18: 86.7: 45.22
+	Hs
		714326 HSP74_HUMAN (1-858): 0: 917: 60.98		DNJB3_HUMAN (381-485): 1.24e-16: 78.6: 40.68
+	Hs
		714317 HSP74_HUMAN (1-858): 0: 917: 60.98		DNJB8_HUMAN (381-482): 1.21e-15: 78.2: 44.35
+	Hs
		714418 HSP74_HUMAN (1-858): 0: 917: 60.98		RPAP3_HUMAN (2-223): 2.82e-09: 61.6: 11.92
+	Hs
		714148 HSP74_HUMAN (1-858): 0: 917: 60.98		PPP5_HUMAN (242-391): 7.28e-09: 60.1: 31.79
+	Dm
		1371973 Q9VUC1_DROME (1-844): 0: 821: 42.13		Q9VPN5_DROME (7-171): 3.79e-22: 101: 29.09
+	Sc
		542113 HSP7F_YEAST (5-730): 7.71e-136: 422: 36.92		CYC8_YEAST (28-406): 2.74e-32: 133: 15.07
+	Hs
		1028128 HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41		DNJC3_HUMAN (14-289): 8.21e-26: 112: 17.83
+	Hs
		685137 HYOU1_HUMAN (1-839): 2.83e-81: 284: 27.41		STIP1_HUMAN (4-156): 5.02e-23: 104: 25.49
+	Dm
		220786 O46067_DROME (2-844): 1.56e-77: 272: 27.86		Q9VHA8_DROME (4-282): 8.56e-12: 69.3: 13.77