HitPredict

Interactor 1: WASL (O00401)
Actin nucleation-promoting factor WASL (Neural Wiskott-Aldrich syndrome protein) (N-WASP)
Gene: WASL

Interactor 2: BIN1 (O00499)
Myc box-dependent-interacting protein 1 (Amphiphysin II) (Amphiphysin-like protein) (Box-dependent myc-interacting protein 1) (Bridging integrator 1)
Gene: BIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	25262827
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0015629 - actin cytoskeleton and 1 others more... GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 505 Hs			1 593
+	Rn
		139991 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		BIN1_RAT (1-592): 2.1e-127: 388: 93.59
+	Hs
		131177 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		BIN1_HUMAN (1-593): 1.03e-133: 404: 100.00
+	Mm
		139043 WASL_MOUSE (379-485): 1.86e-30: 125: 95.33		BIN1_MOUSE (1-592): 3.79e-129: 393: 94.10
+	Dm
		1180683 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q7KLE5_DROME (6-592): 6.45e-67: 230: 24.57
+	Hs
		790671 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		SRC8_HUMAN (14-591): 1.39e-77: 257: 16.72
+	Hs
		126934 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		SRC8_HUMAN (14-591): 1.39e-77: 257: 16.72
+	Mm
		1141101 WASL_MOUSE (379-485): 1.86e-30: 125: 95.33		SRC8_MOUSE (14-591): 3.51e-76: 253: 15.22
+	Dm
		1361428 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		DBNL_DROME (118-592): 5.39e-39: 152: 14.11
+	Rn
		139978 SYNJ1_RAT (4-505): 7.74e-69: 241: 13.31		AMPH_RAT (44-592): 1.56e-19: 94.9: 16.52
+	Dm
		112580 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		M9ND00_DROME (322-591): 2.06e-32: 135: 16.49
+	Dm
		1361426 Q9VAT0_DROME (1-504): 8.78e-57: 199: 31.37		Q9VIF7_DROME (322-591): 2.41e-30: 129: 16.49
+	Rn
		139963 WASL_RAT (379-485): 3.36e-30: 125: 95.33		SRC8_RAT (14-591): 1.17e-55: 198: 12.95
+	Hs
		203213 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		AMPH_HUMAN (44-592): 1.49e-21: 101: 15.13
+	Hs
		203228 SYNJ1_HUMAN (4-500): 4.14e-62: 222: 14.85		ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69
+	Hs
		166056 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN2_HUMAN (2-593): 2.37e-12: 72.5: 11.45
+	Hs
		166049 SYNJ2_HUMAN (3-471): 6.56e-60: 215: 14.85		ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69
+	Hs
		790688 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN2_HUMAN (2-593): 2.37e-12: 72.5: 11.45
+	Hs
		790676 WASP_HUMAN (16-313): 7.4e-38: 147: 44.41		ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69
+	Hs
		126936 WASL_HUMAN (378-485): 2.86e-29: 122: 100.00		ITSN1_HUMAN (3-591): 1.85e-11: 69.4: 13.69
+	Rn
		94091 F1LSG0_RAT (379-485): 2.85e-30: 125: 95.33		ITSN1_RAT (3-591): 8.65e-10: 64: 13.34