HitPredict

Interactor 1: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Interactor 2: NECT2 (Q92692)
Nectin-2 (Herpes virus entry mediator B) (Herpesvirus entry mediator B) (HveB) (Nectin cell adhesion molecule 2) (Poliovirus receptor-related protein 2) (CD antigen CD112)
Gene: NECTIN2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.968

The method score is based on:

Property Details
Experiments 10617658, 9845526, 21982860, 22902367, 22927415, 28515320, 23758976
Identification Methods affinity chromatography technology, pull down, surface plasmon resonance, cosedimentation in solution, molecular sieving, x-ray crystallography, protein array, enzyme linked immunosorbent assay
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~V-set, V-set~V-set
Common GO terms GO:0001618 - virus receptor activity
GO:0001675 - acrosome assembly
GO:0002860 - positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
GO:0002891 - positive regulation of immunoglobulin mediated immune response
GO:0005886 - plasma membrane
and 29 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 538
Hs

1 538
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Last updated: 15 Jul 2024