Interactor 1: CSN8 (Q7KTH8)
COP9 signalosome complex subunit 8 (Dch8) (Signalosome subunit 8)
Gene: CSN8

Interactor 2: CSN3 (Q8SYG2)
COP9 signalosome complex subunit 3 (Dch3) (Signalosome subunit 3)
Gene: CSN3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.744

The method score is based on:

Property Details
Experiments 14605208, 38944040
Identification Methods two hybrid, anti tag coimmunoprecipitation
Interaction Type direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains COP9_hel_rpt~CSN8_PSD8_EIF3K, CSN8_PSD8_EIF3K~PCI
Common GO terms GO:0000338 - protein deneddylation
GO:0005737 - cytoplasm
GO:0008180 - COP9 signalosome
GO:0050821 - protein stabilization
Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 182
Dm

1 445
+ Hs
+ At
+ Hs
+ Mm
+ Dm

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Last updated: 11Aug2025