Protein: CSN2
COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15)

Gene: CSN2, Cops2
Organism: Mus musculus
Interactions: 23
UniProt ID: P61202

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000338 - protein deneddylation
GO:0001833 - inner cell mass cell proliferation
GO:0001834 - trophectodermal cell proliferation
GO:0003714 - transcription corepressor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

107991

G3UXW9
COP9 signalosome complex subunit 1

2

19

Small-scale

0.754

High

312542

CSN3
COP9 signalosome complex subunit 3

1

20

Small-scale

0.618

High

312554

CSN4
COP9 signalosome complex subunit 4

1

20

Small-scale

0.618

High

312564

CSN6
COP9 signalosome complex subunit 6

1

20

Small-scale

0.618

High

958750

CSN8
COP9 signalosome complex subunit 8

1

10

Small-scale

0.618

High

958751

CSN7A
COP9 signalosome complex subunit 7a

1

20

Small-scale

0.618

High

663009

HXD12
Homeobox protein Hox-D12

1

1

High-throughput

0.541

High

704246

NP1L1
Nucleosome assembly protein 1-like 1

1

1

Small-scale

0.481

High

109305

G5E8N3
Histone-lysine N-methyltransferase SETDB1

1

2

Small-scale

0.479

High

205254

AXIN1
Axin-1

1

1

Small-scale

0.479

High

205606

CSN5
COP9 signalosome complex subunit 5

1

20

Small-scale

0.479

High

927656

ATX1
Ataxin-1

1

3

High-throughput

0.479

High

958744

RBX1
E3 ubiquitin-protein ligase RBX1

1

5

Small-scale

0.479

High

958746

FBW1A
F-box/WD repeat-containing protein 1A

1

4

Small-scale

0.479

High

958747

WDTC1
WD and tetratricopeptide repeats protein 1

1

14

High-throughput

0.479

High

958753

GSK3B
Glycogen synthase kinase-3 beta

1

3

Small-scale

0.479

High

958745

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

958749

Q8BNP7
Adenomatous polyposis coli protein

1

0

Small-scale

0.458

High

509009

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin; Ubiquitin-related 1; Ubiquitin-related 2]

1

20

High-throughput

0.457

High

958752

CUL1
Cullin-1

1

20

Small-scale

0.437

High

551400

A4
Amyloid-beta precursor protein

1

5

Small-scale

0.408

High

958748

KC1A
Casein kinase I isoform alpha

1

0

Small-scale

0.261

Low

312628

LRP6
Low-density lipoprotein receptor-related protein 6

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025