HitPredict

Interactor 1: BT2A1 (Q7KYR7)
Butyrophilin subfamily 2 member A1
Gene: BTN2A1

Interactor 2: TMX1 (Q9H3N1)
Thioredoxin-related transmembrane protein 1 (Protein disulfide-isomerase TMX1) (EC 5.3.4.1) (Thioredoxin domain-containing protein 1) (Transmembrane Trx-related protein)
Gene: TMX1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.80	0.618

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Thioredoxin~V-set
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 527 Hs			1 280
+	Hs
		1270283 BT2A1_HUMAN (1-527): 3.6e-154: 452: 100.00		TMX4_HUMAN (20-261): 3.22e-53: 178: 41.98
+	Hs
		717463 BT1A1_HUMAN (27-511): 2.98e-135: 403: 46.91		PDIA3_HUMAN (147-269): 6.26e-15: 76.3: 11.29
+	Hs
		1221115 CD276_HUMAN (21-243): 6.74e-61: 211: 23.04		TMX1_HUMAN (1-280): 3.89e-79: 242: 100.00
+	Hs
		1432767 PD1L1_HUMAN (14-291): 5.4e-62: 206: 19.72		TMX1_HUMAN (1-280): 3.89e-79: 242: 100.00
+	Hs
		623510 RO52_HUMAN (297-510): 1.57e-70: 234: 43.89		ERP44_HUMAN (1-161): 1.6e-38: 141: 23.12
+	Hs
		623353 RO52_HUMAN (297-510): 1.57e-70: 234: 43.89		PDIA6_HUMAN (25-146): 2.92e-34: 130: 31.01
+	Hs
		623447 RO52_HUMAN (297-510): 1.57e-70: 234: 43.89		TXND5_HUMAN (24-135): 7.67e-33: 126: 25.86
+	Hs
		1334138 PD1L1_HUMAN (14-291): 5.4e-62: 206: 19.72		TXND5_HUMAN (24-135): 7.67e-33: 126: 25.86
+	Hs
		566546 RO52_HUMAN (297-510): 1.57e-70: 234: 43.89		PDIA4_HUMAN (119-266): 1.21e-16: 81.3: 9.68
+	Hs
		623129 RO52_HUMAN (297-510): 1.57e-70: 234: 43.89		PDIA3_HUMAN (147-269): 6.26e-15: 76.3: 11.29
+	Hs
		452161 RO52_HUMAN (297-510): 1.57e-70: 234: 43.89		PDIA1_HUMAN (66-256): 3.31e-10: 62.1: 10.68
+	Hs
		717626 PD1L1_HUMAN (14-291): 5.4e-62: 206: 19.72		PDIA3_HUMAN (147-269): 6.26e-15: 76.3: 11.29