Protein: SNX6
Sorting nexin-6 (TRAF4-associated factor 2) [Cleaved into: Sorting nexin-6, N-terminally processed]

Gene: SNX6
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q9UNH7

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1040533

SNX1
Sorting nexin-1

9

19

Small-scale

0.973

High

240456

SNX2
Sorting nexin-2

7

19

Small-scale

0.963

High

1357510

DYN3
Dynamin-3

3

13

High-throughput

0.861

High

1204251

SNX32
Sorting nexin-32

2

15

High-throughput

0.811

High

310865

VAPB
Vesicle-associated membrane protein-associated protein B/C

3

3

High-throughput

0.667

High

905407

UBP46
Ubiquitin carboxyl-terminal hydrolase 46

3

1

High-throughput

0.667

High

1191347

CMKMT
Calmodulin-lysine N-methyltransferase

3

2

High-throughput

0.667

High

1239134

CAST3
Putative protein CASTOR3P

3

1

High-throughput

0.667

High

1344831

DISC1
Disrupted in schizophrenia 1 protein

3

4

High-throughput

0.661

High

1328223

TSYL1
Testis-specific Y-encoded-like protein 1

3

0

High-throughput

0.646

High

507590

PIM1
Serine/threonine-protein kinase pim-1

2

5

Small-scale

0.631

High

1135185

HENMT
Small RNA 2'-O-methyltransferase

2

1

High-throughput

0.628

High

1261512

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

2

1

High-throughput

0.628

High

1262260

DYT2B
Dynein light chain Tctex-type protein 2B

2

1

High-throughput

0.628

High

1295923

UBP47
Ubiquitin carboxyl-terminal hydrolase 47

2

1

High-throughput

0.628

High

307919

SNX4
Sorting nexin-4

1

18

Small-scale

0.618

High

1296959

SNX27
Sorting nexin-27

1

3

High-throughput

0.618

High

1331625

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.618

High

1357509

SNX7
Sorting nexin-7

1

19

Small-scale

0.618

High

59525

F221A
Protein FAM221A

3

2

High-throughput

0.609

High

1132809

TRML2
Trem-like transcript 2 protein

3

1

High-throughput

0.609

High

1326033

NDEL1
Nuclear distribution protein nudE-like 1

2

1

High-throughput

0.590

High

206166

TGON2
Trans-Golgi network integral membrane protein 2

2

8

High-throughput

0.588

High

1075224

TEAD4
Transcriptional enhancer factor TEF-3

2

0

High-throughput

0.585

High

229062

PRKN
E3 ubiquitin-protein ligase parkin

2

11

High-throughput

0.584

High

507313

LAMP1
Lysosome-associated membrane glycoprotein 1

2

15

High-throughput

0.584

High

592061

RAB4A
Ras-related protein Rab-4A

2

11

High-throughput

0.584

High

845805

RAB9A
Ras-related protein Rab-9A

2

17

High-throughput

0.584

High

914459

RB11A
Ras-related protein Rab-11A

2

9

High-throughput

0.584

High

1356409

TNIK
TRAF2 and NCK-interacting protein kinase

2

5

High-throughput

0.576

High

361951

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

2

1

High-throughput

0.574

High

1042841

CUL3
Cullin-3

1

3

Small-scale

0.561

High

842722

RL14
Large ribosomal subunit protein eL14

2

0

High-throughput

0.559

High

1223143

TEX11
Testis-expressed protein 11

2

2

High-throughput

0.553

High

587060

CSK22
Casein kinase II subunit alpha'

1

1

High-throughput

0.541

High

1078933

ITSN1
Intersectin-1

1

5

High-throughput

0.541

High

1287429

OPTN
Optineurin

1

7

High-throughput

0.541

High

536591

HCLS1
Hematopoietic lineage cell-specific protein

1

10

High-throughput

0.536

High

847927

BRCA2
Breast cancer type 2 susceptibility protein

1

1

High-throughput

0.536

High

874013

S12A3
Solute carrier family 12 member 3

1

3

High-throughput

0.536

High

1051513

DCTN1
Dynactin subunit 1

1

1

Small-scale

0.536

High

1078067

HERC1
Probable E3 ubiquitin-protein ligase HERC1

1

4

High-throughput

0.536

High

1147907

C102B
Coiled-coil domain-containing protein 102B

1

4

High-throughput

0.536

High

1168474

STAC2
SH3 and cysteine-rich domain-containing protein 2

1

18

High-throughput

0.536

High

1218023

CBCO1
Ciliary-associated calcium-binding coiled-coil protein 1

1

2

High-throughput

0.536

High

1260720

PRUN2
Protein prune homolog 2

1

2

High-throughput

0.536

High

1306181

NPAS1
Neuronal PAS domain-containing protein 1

1

2

High-throughput

0.536

High

1311817

INP5K
Inositol polyphosphate 5-phosphatase K

1

4

High-throughput

0.536

High

1331995

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

6

High-throughput

0.536

High

1344022

BIRC6
Baculoviral IAP repeat-containing protein 6

1

2

High-throughput

0.536

High

1344318

KLHL1
Kelch-like protein 1

1

4

High-throughput

0.536

High

1355629

NRBP
Nuclear receptor-binding protein

1

3

High-throughput

0.536

High

1357286

SPAT2
Spermatogenesis-associated protein 2

1

1

High-throughput

0.536

High

1357512

NTNG1
Netrin-G1

1

6

High-throughput

0.536

High

155477

NRP1
Neuropilin-1

1

5

High-throughput

0.527

High

1336549

BRMS1
Breast cancer metastasis-suppressor 1

1

0

Small-scale

0.526

High

1255338

MIPT3
TRAF3-interacting protein 1

2

1

High-throughput

0.516

High

364477

TFR1
Transferrin receptor protein 1

1

3

High-throughput

0.515

High

396051

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.515

High

300980

HAUS5
HAUS augmin-like complex subunit 5

1

0

High-throughput

0.513

High

933665

TBA4A
Tubulin alpha-4A chain

1

0

High-throughput

0.513

High

1030553

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1031642

ATM
Serine-protein kinase ATM

1

0

High-throughput

0.513

High

1264554

ATG4A
Cysteine protease ATG4A

1

0

High-throughput

0.513

High

1295249

SPTCS
Spatacsin

1

0

High-throughput

0.513

High

1357514

MTCL1
Microtubule cross-linking factor 1

1

0

High-throughput

0.513

High

48884

POTB3
POTE ankyrin domain family member B3

2

5

High-throughput

0.504

High

175303

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

4

High-throughput

0.501

High

370709

ESR1
Estrogen receptor

1

3

Small-scale

0.501

High

180610

TEX28
Testis-specific protein TEX28

1

1

High-throughput

0.489

High

602936

BMP6
Bone morphogenetic protein 6

1

3

High-throughput

0.489

High

1103729

DB136
Defensin beta 136

1

3

High-throughput

0.489

High

1203407

TMPSC
Transmembrane protease serine 12

1

2

High-throughput

0.489

High

1263156

IBPL1
Insulin-like growth factor-binding protein-like 1

1

7

High-throughput

0.489

High

1357515

WIF1
Wnt inhibitory factor 1

1

2

High-throughput

0.489

High

750538

COIL
Coilin

1

0

High-throughput

0.486

High

749955

BRCA1
Breast cancer type 1 susceptibility protein

1

5

High-throughput

0.481

High

882056

BACE1
Beta-secretase 1

1

0

Small-scale

0.479

High

118622

EYA2
Eyes absent homolog 2

1

2

High-throughput

0.479

High

151257

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

3

High-throughput

0.479

High

178862

STX7
Syntaxin-7

1

7

High-throughput

0.479

High

213060

STX6
Syntaxin-6

1

3

High-throughput

0.479

High

234448

NRP2
Neuropilin-2

1

5

High-throughput

0.479

High

258248

DNJB6
DnaJ homolog subfamily B member 6

1

4

High-throughput

0.479

High

296776

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.479

High

320061

HERC2
E3 ubiquitin-protein ligase HERC2

1

4

High-throughput

0.479

High

339134

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.479

High

349007

RASN
GTPase NRas

1

17

High-throughput

0.479

High

349732

RASH
GTPase HRas

1

14

High-throughput

0.479

High

350684

RASK
GTPase KRas

1

17

High-throughput

0.479

High

373445

CATA
Catalase

1

1

High-throughput

0.479

High

411527

INSR
Insulin receptor

1

20

Small-scale

0.479

High

411888

LCK
Tyrosine-protein kinase Lck

1

13

High-throughput

0.479

High

417452

ENOA
Alpha-enolase

1

1

High-throughput

0.479

High

430381

PROF1
Profilin-1

1

1

High-throughput

0.479

High

435805

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

504957

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

508266

FGFR1
Fibroblast growth factor receptor 1

1

14

High-throughput

0.479

High

514937

MPRI
Cation-independent mannose-6-phosphate receptor

1

2

High-throughput

0.479

High

527886

LAMP2
Lysosome-associated membrane glycoprotein 2

1

15

High-throughput

0.479

High

547280

EZRI
Ezrin

1

1

High-throughput

0.479

High

557294

PGFRA
Platelet-derived growth factor receptor alpha

1

15

Small-scale

0.479

High

567328

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.479

High

568830

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

2

High-throughput

0.479

High

570183

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

592580

RAB5A
Ras-related protein Rab-5A

1

14

High-throughput

0.479

High

636531

DNJB2
DnaJ homolog subfamily B member 2

1

7

High-throughput

0.479

High

670283

MARCS
Myristoylated alanine-rich C-kinase substrate

1

3

High-throughput

0.479

High

729384

VGFR3
Vascular endothelial growth factor receptor 3

1

14

High-throughput

0.479

High

738592

TGFR1
TGF-beta receptor type-1

1

8

Small-scale

0.479

High

740085

TGFR2
TGF-beta receptor type-2

1

8

Small-scale

0.479

High

782010

PERI
Peripherin

1

1

High-throughput

0.479

High

844798

RAB5C
Ras-related protein Rab-5C

1

14

High-throughput

0.479

High

913188

ARF6
ADP-ribosylation factor 6

1

6

High-throughput

0.479

High

916075

RHOB
Rho-related GTP-binding protein RhoB

1

6

High-throughput

0.479

High

940601

CXAR
Coxsackievirus and adenovirus receptor

1

1

High-throughput

0.479

High

1036541

MTM1
Myotubularin

1

4

High-throughput

0.479

High

1044952

AVR2B
Activin receptor type-2B

1

8

Small-scale

0.479

High

1058067

RRP5
Protein RRP5 homolog

1

3

High-throughput

0.479

High

1069878

PTPRR
Receptor-type tyrosine-protein phosphatase R

1

1

High-throughput

0.479

High

1070457

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

1138342

MYOME
Myomegalin

1

1

High-throughput

0.479

High

1152192

LTOR1
Ragulator complex protein LAMTOR1

1

8

High-throughput

0.479

High

1172263

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1188447

ATG9A
Autophagy-related protein 9A

1

3

High-throughput

0.479

High

1189041

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

5

High-throughput

0.479

High

1240362

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1240839

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

1267253

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

1284671

VP33A
Vacuolar protein sorting-associated protein 33A

1

1

High-throughput

0.479

High

1301923

CCNL2
Cyclin-L2

1

2

High-throughput

0.479

High

1305313

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

1313641

LRC61
Leucine-rich repeat-containing protein 61

1

2

High-throughput

0.479

High

1330442

DNJC5
DnaJ homolog subfamily C member 5

1

11

High-throughput

0.479

High

1350526

ANFY1
Rabankyrin-5

1

6

High-throughput

0.479

High

1354860

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1357047

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

2

High-throughput

0.479

High

1357470

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

High-throughput

0.479

High

1357511

LAMP3
Lysosome-associated membrane glycoprotein 3

1

15

High-throughput

0.479

High

1357513

GIT1
ARF GTPase-activating protein GIT1

1

4

Small-scale

0.479

High

155156

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.458

High

279759

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

305678

ZFPL1
Zinc finger protein-like 1

1

0

High-throughput

0.458

High

1056165

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

1086038

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1230904

ZN687
Zinc finger protein 687

1

0

High-throughput

0.458

High

1285787

CHCH1
Small ribosomal subunit protein mS37

1

0

High-throughput

0.458

High

1327610

TOLIP
Toll-interacting protein

1

0

High-throughput

0.458

High

989192

FMR1
Fragile X messenger ribonucleoprotein 1

1

2

High-throughput

0.457

High

382563

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

1

High-throughput

0.445

High

402619

JUN
Transcription factor Jun

1

3

High-throughput

0.445

High

497802

TAU
Microtubule-associated protein tau

1

4

High-throughput

0.445

High

122299

BMR1B
Bone morphogenetic protein receptor type-1B

1

8

Small-scale

0.437

High

169665

BET1
BET1 homolog

1

3

High-throughput

0.437

High

318252

DIRA3
GTP-binding protein Di-Ras3

1

6

High-throughput

0.437

High

434311

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

18

High-throughput

0.437

High

456963

FURIN
Furin

1

1

High-throughput

0.437

High

721775

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

739536

ACVL1
Serine/threonine-protein kinase receptor R3

1

8

Small-scale

0.437

High

793528

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.437

High

817335

LEPR
Leptin receptor

1

4

Small-scale

0.437

High

872507

EPHA5
Ephrin type-A receptor 5

1

17

High-throughput

0.437

High

884616

RAB25
Ras-related protein Rab-25

1

9

High-throughput

0.437

High

1081649

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.437

High

1084241

OCLN
Occludin

1

2

High-throughput

0.437

High

1127727

PRC2B
Protein PRRC2B

1

3

High-throughput

0.437

High

1223427

ZDH23
Palmitoyltransferase ZDHHC23

1

5

Small-scale

0.437

High

1283102

CK052
Uncharacterized protein C11orf52

1

1

High-throughput

0.437

High

1309801

GORS1
Golgi reassembly-stacking protein 1

1

1

High-throughput

0.437

High

1329324

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

2

High-throughput

0.437

High

1330989

RHOJ
Rho-related GTP-binding protein RhoJ

1

8

High-throughput

0.437

High

1345917

ZDH18
Palmitoyltransferase ZDHHC18

1

2

Small-scale

0.437

High

1348614

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.437

High

1349869

SEP10
Septin-10

1

1

High-throughput

0.437

High

1354631

DNJ5B
DnaJ homolog subfamily C member 5B

1

11

High-throughput

0.437

High

1169924

PKHG7
Pleckstrin homology domain-containing family G member 7

1

2

High-throughput

0.407

High

560367

EPB42
Protein 4.2

2

0

High-throughput

0.328

High

450676

PAEP
Glycodelin

1

0

High-throughput

0.279

Low

132633

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

393388

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

0

Small-scale

0.249

Low

881697

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

1231781

FA43A
Protein FAM43A

1

0

High-throughput

0.249

Low

1282671

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.249

Low

1287803

HAVR1
Hepatitis A virus cellular receptor 1

1

0

Small-scale

0.249

Low

1239882

GOLM1
Golgi membrane protein 1

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024