Protein: CD276
CD276 antigen (4Ig-B7-H3) (B7 homolog 3) (B7-H3) (Costimulatory molecule) (CD antigen CD276)

Gene: CD276
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q5ZPR3

Gene Ontology (top 5):
GO:0001817 - regulation of cytokine production
GO:0005102 - signaling receptor binding
GO:0009897 - external side of plasma membrane
GO:0016020 - membrane
GO:0032729 - positive regulation of type II interferon production

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

127350

LEG8
Galectin-8

3

7

High-throughput

0.861

High

1186204

CEA21
Cell adhesion molecule CEACAM21

2

18

High-throughput

0.811

High

1221116

CLC5A
C-type lectin domain family 5 member A

3

6

High-throughput

0.770

High

374675

RASH
GTPase HRas

2

20

High-throughput

0.754

High

1221115

TMX1
Thioredoxin-related transmembrane protein 1

2

11

High-throughput

0.726

High

480820

LEG1
Galectin-1

2

7

High-throughput

0.694

High

125494

LEG9
Galectin-9

1

7

High-throughput

0.691

High

378117

TNFA
Tumor necrosis factor

1

1

High-throughput

0.691

High

760760

CD68
Macrosialin

1

1

High-throughput

0.691

High

1221111

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.628

High

1221110

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.618

High

1221112

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

1

7

High-throughput

0.618

High

1221119

PCDA9
Protocadherin alpha-9

1

8

High-throughput

0.618

High

373990

RASN
GTPase NRas

1

20

High-throughput

0.618

High

375609

RASK
GTPase KRas

1

20

High-throughput

0.618

High

761243

RYK
Tyrosine-protein kinase RYK

2

20

Small-scale

0.611

High

211138

CTR4
Cationic amino acid transporter 4

1

6

High-throughput

0.575

High

256053

S19A2
Thiamine transporter 1

1

2

High-throughput

0.575

High

609705

LEG3
Galectin-3

1

7

High-throughput

0.575

High

641959

CD9
CD9 antigen

1

7

High-throughput

0.575

High

722486

CTR1
High affinity cationic amino acid transporter 1

1

6

High-throughput

0.575

High

1221114

MF14A
Hippocampus abundant transcript 1 protein

1

3

High-throughput

0.575

High

1116755

AAMP
Angio-associated migratory cell protein

1

4

Small-scale

0.553

High

1221109

TRI67
Tripartite motif-containing protein 67

1

17

High-throughput

0.553

High

870243

S6A12
Sodium- and chloride-dependent betaine transporter

1

0

High-throughput

0.546

High

349442

TSN15
Tetraspanin-15

1

7

High-throughput

0.514

High

170804

CLGN
Calmegin

1

9

High-throughput

0.489

High

1187198

CC50B
Cell cycle control protein 50B

1

2

High-throughput

0.489

High

1206265

NHLC3
NHL repeat-containing protein 3

1

3

High-throughput

0.489

High

1221117

FBX2
F-box only protein 2

1

8

High-throughput

0.489

High

1131959

MVP
Major vault protein

1

0

Small-scale

0.458

High

1221113

CTL1
Choline transporter-like protein 1

1

2

High-throughput

0.445

High

218308

TGON2
Trans-Golgi network integral membrane protein 2

1

9

High-throughput

0.437

High

1004696

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.437

High

529953

TAU
Microtubule-associated protein tau

1

10

High-throughput

0.407

High

1221118

WASC3
WASH complex subunit 3

1

0

High-throughput

0.279

Low

1045392

TF65
Transcription factor p65

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025