HitPredict

Interactor 1: DLG3 (Q92796)
Disks large homolog 3 (Neuroendocrine-DLG) (Synapse-associated protein 102) (SAP-102) (SAP102) (XLMR)
Gene: DLG3

Interactor 2: DLGP2 (Q9P1A6)
Disks large-associated protein 2 (DAP-2) (PSD-95/SAP90-binding protein 2) (SAP90/PSD-95-associated protein 2) (SAPAP2)
Gene: DLGAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.653

Property	Details
Experiments	32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 817 Hs			1 1054
+	Hs
		4619 DLG3_HUMAN (1-817): 0: 713: 100.00		A0A1B0GTN4_HUMAN (5-1054): 0: 1540: 99.91
+	Rn
		957001 DLG3_RAT (1-817): 0: 689: 95.17		DLGP2_RAT (1-1054): 0: 1482: 89.14
+	Hs
		1021580 DLG1_HUMAN (13-817): 0: 586: 63.90		DLGP2_HUMAN (1-1054): 0: 1549: 100.00
+	Hs
		4617 DLG1_HUMAN (13-817): 0: 586: 63.90		A0A1B0GTN4_HUMAN (5-1054): 0: 1540: 99.91
+	Rn
		957000 DLG1_RAT (3-817): 0: 578: 61.42		DLGP2_RAT (1-1054): 0: 1482: 89.14
+	Hs
		145952 DLG3_HUMAN (1-817): 0: 713: 100.00		DLGP1_HUMAN (80-1054): 0: 1202: 52.16
+	Rn
		956990 DLG3_RAT (1-817): 0: 689: 95.17		DLGP1_RAT (80-1054): 0: 1184: 51.11
+	Mm
		936189 DLG3_MOUSE (1-817): 0: 689: 95.05		DLGP1_MOUSE (80-1054): 0: 1180: 51.11
+	Hs
		145947 DLG1_HUMAN (13-817): 0: 586: 63.90		DLGP1_HUMAN (80-1054): 0: 1202: 52.16
+	Mm
		1195008 DLG1_MOUSE (3-817): 0: 592: 62.63		DLGP1_MOUSE (80-1054): 0: 1180: 51.11
+	Rn
		956989 DLG1_RAT (3-817): 0: 578: 61.42		DLGP1_RAT (80-1054): 0: 1184: 51.11
+	Rn
		957006 DLG3_RAT (1-817): 0: 689: 95.17		DLGP3_RAT (80-1054): 0: 1041: 44.81
+	Hs
		1271042 DLG3_HUMAN (1-817): 0: 713: 100.00		DLGP4_HUMAN (80-1054): 0: 955: 42.72
+	Rn
		957005 DLG1_RAT (3-817): 0: 578: 61.42		DLGP3_RAT (80-1054): 0: 1041: 44.81
+	Rn
		957009 DLG3_RAT (1-817): 0: 689: 95.17		DLGP4_RAT (80-1054): 0: 908: 41.55
+	Hs
		1021594 DLG1_HUMAN (13-817): 0: 586: 63.90		DLGP4_HUMAN (80-1054): 0: 955: 42.72
+	Rn
		957008 DLG1_RAT (3-817): 0: 578: 61.42		DLGP4_RAT (80-1054): 0: 908: 41.55
+	Hs
		1153634 DLG3_HUMAN (1-817): 0: 713: 100.00		Q6IS01_HUMAN (80-607): 0: 709: 52.17
+	Hs
		145945 DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25		DLGP1_HUMAN (80-1054): 0: 1202: 52.16
+	Hs
		327234 DLG4_HUMAN (50-285): 9.84e-26: 115: 20.25		DLGP3_HUMAN (80-1054): 0: 1074: 45.72