Protein: TRM7
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase (EC 2.1.1.205) (2'-O-ribose RNA methyltransferase TRM7 homolog) (Protein ftsJ homolog 1)

Gene: TRM7, FTSJ1
Organism: Homo sapiens
Interactions: 180
UniProt ID: Q9UET6

Gene Ontology (top 5):
GO:0002128 - tRNA nucleoside ribose methylation
GO:0002130 - wobble position ribose methylation
GO:0002181 - cytoplasmic translation
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1445745

WDR6
tRNA

4

7

High-throughput

0.895

High

1066253

DMWD
Dystrophia myotonica WD repeat-containing protein

1

4

High-throughput

0.691

High

1450715

GNL3L
Guanine nucleotide-binding protein-like 3-like protein

2

4

High-throughput

0.628

High

1066531

RBBP4
Histone-binding protein RBBP4

1

3

High-throughput

0.618

High

1450207

DCA13
DDB1- and CUL4-associated factor 13

1

5

Small-scale

0.618

High

376054

RASK
GTPase KRas

2

4

High-throughput

0.584

High

1459033

CERT
Ceramide transfer protein

2

0

High-throughput

0.580

High

699883

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

1

High-throughput

0.571

High

889674

CLK2
Dual specificity protein kinase CLK2

1

1

High-throughput

0.536

High

1114557

CUL3
Cullin-3

1

4

High-throughput

0.536

High

1158585

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.536

High

1395490

ZFP91
E3 ubiquitin-protein ligase ZFP91

1

1

High-throughput

0.536

High

710544

EPHA2
Ephrin type-A receptor 2

2

7

High-throughput

0.533

High

1292979

AROS
Active regulator of SIRT1

1

0

High-throughput

0.513

High

1310496

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

411103

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

5

High-throughput

0.500

High

412753

NTRK1
High affinity nerve growth factor receptor

1

7

High-throughput

0.489

High

1258270

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

2

High-throughput

0.489

High

1291949

WDR5B
WD repeat-containing protein 5B

1

2

High-throughput

0.489

High

423389

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

132361

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

226903

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

1

High-throughput

0.479

High

344352

PTBP3
Polypyrimidine tract-binding protein 3

1

5

High-throughput

0.479

High

374257

RASN
GTPase NRas

1

4

High-throughput

0.479

High

401650

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

540730

LAMP1
Lysosome-associated membrane glycoprotein 1

1

1

High-throughput

0.479

High

552720

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.479

High

568304

PLST
Plastin-3

1

2

High-throughput

0.479

High

593524

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.479

High

633813

PSB1
Proteasome subunit beta type-1

1

3

High-throughput

0.479

High

646958

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

1

High-throughput

0.479

High

656265

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

2

High-throughput

0.479

High

681063

PSA1
Proteasome subunit alpha type-1

1

1

High-throughput

0.479

High

681540

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.479

High

685757

U2AF2
Splicing factor U2AF 65 kDa subunit

1

6

High-throughput

0.479

High

710669

EPHA3
Ephrin type-A receptor 3

1

7

High-throughput

0.479

High

718036

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.479

High

831588

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

842881

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

1

High-throughput

0.479

High

860395

RS9
Small ribosomal subunit protein uS4

1

3

High-throughput

0.479

High

881108

NASP
Nuclear autoantigenic sperm protein

1

2

High-throughput

0.479

High

887601

PSB3
Proteasome subunit beta type-3

1

2

High-throughput

0.479

High

910241

RND2
Rho-related GTP-binding protein RhoN

1

9

High-throughput

0.479

High

929843

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

932148

EPHA4
Ephrin type-A receptor 4

1

7

High-throughput

0.479

High

936881

NP1L1
Nucleosome assembly protein 1-like 1

1

2

High-throughput

0.479

High

946470

MTPN
Myotrophin

1

1

High-throughput

0.479

High

953735

RAC3
Ras-related C3 botulinum toxin substrate 3

1

4

High-throughput

0.479

High

954923

PSA6
Proteasome subunit alpha type-6

1

1

High-throughput

0.479

High

955718

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

960008

RS3A
Small ribosomal subunit protein eS1

1

2

High-throughput

0.479

High

960287

RL26
Large ribosomal subunit protein uL24

1

3

High-throughput

0.479

High

960598

PSME3
Proteasome activator complex subunit 3

1

1

High-throughput

0.479

High

962596

RHOA
Transforming protein RhoA

1

4

High-throughput

0.479

High

962850

RND3
Rho-related GTP-binding protein RhoE

1

8

High-throughput

0.479

High

965591

NTF2
Nuclear transport factor 2

1

3

High-throughput

0.479

High

968825

PRS4
26S proteasome regulatory subunit 4

1

1

High-throughput

0.479

High

971239

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

973617

RS11
Small ribosomal subunit protein uS17

1

2

High-throughput

0.479

High

975517

PRS10
26S proteasome regulatory subunit 10B

1

1

High-throughput

0.479

High

976634

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

977101

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

1

High-throughput

0.479

High

978377

RHOB
Rho-related GTP-binding protein RhoB

1

5

High-throughput

0.479

High

982140

RAP1A
Ras-related protein Rap-1A

1

4

High-throughput

0.479

High

988793

RAC1
Ras-related C3 botulinum toxin substrate 1

1

4

High-throughput

0.479

High

1087607

GRSF1
G-rich sequence factor 1

1

6

High-throughput

0.479

High

1089359

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

1

High-throughput

0.479

High

1140988

KIF14
Kinesin-like protein KIF14

1

2

High-throughput

0.479

High

1144205

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.479

High

1151916

RHOH
Rho-related GTP-binding protein RhoH

1

6

High-throughput

0.479

High

1154950

NEDD8
Ubiquitin-like protein NEDD8

1

1

High-throughput

0.479

High

1159552

NTRK2
BDNF/NT-3 growth factors receptor

1

7

High-throughput

0.479

High

1271035

RHOU
Rho-related GTP-binding protein RhoU

1

7

High-throughput

0.479

High

1329924

SIR6
NAD-dependent protein deacylase sirtuin-6

1

3

High-throughput

0.479

High

1366903

RND1
Rho-related GTP-binding protein Rho6

1

8

High-throughput

0.479

High

1406081

PHB2
Prohibitin-2

1

1

High-throughput

0.479

High

1407935

ANM1
Protein arginine N-methyltransferase 1

1

1

High-throughput

0.479

High

1428761

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

3

High-throughput

0.479

High

1432991

DNJC5
DnaJ homolog subfamily C member 5

1

2

High-throughput

0.479

High

1434144

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1438221

RHOF
Rho-related GTP-binding protein RhoF

1

6

High-throughput

0.479

High

1447389

ANLN
Anillin

1

1

High-throughput

0.479

High

1449710

MDN1
Midasin

1

4

High-throughput

0.479

High

1453300

IF2B1
Insulin-like growth factor 2 mRNA-binding protein 1

1

4

High-throughput

0.479

High

1454477

IBTK
Inhibitor of Bruton tyrosine kinase

1

2

High-throughput

0.479

High

1459024

DNJ5B
DnaJ homolog subfamily C member 5B

1

2

High-throughput

0.479

High

1459028

WWC3
Protein WWC3

1

3

High-throughput

0.479

High

1459030

DRG1
Developmentally-regulated GTP-binding protein 1

1

3

High-throughput

0.479

High

1459032

SRPRB
Signal recognition particle receptor subunit beta

1

1

High-throughput

0.479

High

128332

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

0

High-throughput

0.458

High

164464

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

211071

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.458

High

221218

DNPH1
5-hydroxymethyl-dUMP N-hydrolase

1

0

High-throughput

0.458

High

294478

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

334323

TACC2
Transforming acidic coiled-coil-containing protein 2

1

0

High-throughput

0.458

High

337041

AHSA1
Activator of 90 kDa heat shock protein ATPase homolog 1

1

0

High-throughput

0.458

High

343654

OXSR1
Serine/threonine-protein kinase OSR1

1

0

High-throughput

0.458

High

361932

HPRT
Hypoxanthine-guanine phosphoribosyltransferase

1

0

High-throughput

0.458

High

447886

TPM3
Tropomyosin alpha-3 chain

1

0

High-throughput

0.458

High

452427

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.458

High

456879

ANXA2
Annexin A2

1

0

High-throughput

0.458

High

459923

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.458

High

551317

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

571000

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.458

High

592911

CBR1
Carbonyl reductase [NADPH] 1

1

0

High-throughput

0.458

High

605835

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

0

High-throughput

0.458

High

663456

RIR1
Ribonucleoside-diphosphate reductase large subunit

1

0

High-throughput

0.458

High

701238

PSB5
Proteasome subunit beta type-5

1

0

High-throughput

0.458

High

712298

TKT
Transketolase

1

0

High-throughput

0.458

High

714985

EF1D
Elongation factor 1-delta

1

0

High-throughput

0.458

High

717358

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

High-throughput

0.458

High

724526

GDIA
Rab GDP dissociation inhibitor alpha

1

0

High-throughput

0.458

High

790958

TAGL2
Transgelin-2

1

0

High-throughput

0.458

High

849415

RANG
Ran-specific GTPase-activating protein

1

0

High-throughput

0.458

High

873760

GSH0
Glutamate--cysteine ligase regulatory subunit

1

0

High-throughput

0.458

High

884799

SYSC
Serine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

905245

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

914036

RIDA
2-iminobutanoate/2-iminopropanoate deaminase

1

0

High-throughput

0.458

High

914069

SPSY
Spermine synthase

1

0

High-throughput

0.458

High

975293

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

1004229

CXAR
Coxsackievirus and adenovirus receptor

1

0

High-throughput

0.458

High

1023640

CYC
Cytochrome c

1

0

High-throughput

0.458

High

1023905

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.458

High

1088752

SF3A3
Splicing factor 3A subunit 3

1

0

High-throughput

0.458

High

1109412

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.458

High

1161078

FSCN1
Fascin

1

0

High-throughput

0.458

High

1178442

CL16A
Protein CLEC16A

1

0

High-throughput

0.458

High

1307132

RHPN2
Rhophilin-2

1

0

High-throughput

0.458

High

1309961

MA7D3
MAP7 domain-containing protein 3

1

0

High-throughput

0.458

High

1380779

RL36L
Ribosomal protein eL42-like

1

0

High-throughput

0.458

High

1383142

LRC59
Leucine-rich repeat-containing protein 59

1

0

High-throughput

0.458

High

1416066

THIC
Acetyl-CoA acetyltransferase, cytosolic

1

0

High-throughput

0.458

High

1437967

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

1454294

RCC2
Protein RCC2

1

0

High-throughput

0.458

High

1458615

EIF3K
Eukaryotic translation initiation factor 3 subunit K

1

0

High-throughput

0.458

High

1459027

NUDT5
ADP-sugar pyrophosphatase

1

0

High-throughput

0.458

High

1459029

RUVB1
RuvB-like 1

1

0

High-throughput

0.458

High

117259

K7EL68
Cell division cycle 37, HSP90 cochaperone

1

1

High-throughput

0.445

High

601480

RHOQ
Rho-related GTP-binding protein RhoQ

1

5

High-throughput

0.437

High

648713

FGFR4
Fibroblast growth factor receptor 4

1

12

High-throughput

0.437

High

693121

DPP4
Dipeptidyl peptidase 4

1

1

High-throughput

0.437

High

710773

EPHA8
Ephrin type-A receptor 8

1

7

High-throughput

0.437

High

711952

LTK
Leukocyte tyrosine kinase receptor

1

8

High-throughput

0.437

High

931909

EPHA5
Ephrin type-A receptor 5

1

7

High-throughput

0.437

High

1147457

EPHA7
Ephrin type-A receptor 7

1

7

High-throughput

0.437

High

1235347

STYK1
Tyrosine-protein kinase STYK1

1

6

High-throughput

0.437

High

1459026

STML2
Stomatin-like protein 2, mitochondrial

1

1

High-throughput

0.437

High

1410053

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.426

High

1459034

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

0

High-throughput

0.426

High

75853

B4DDV3
protein acetyllysine N-acetyltransferase

1

3

High-throughput

0.407

High

95879

E7EPI0
Inhibitor of Bruton tyrosine kinase

1

2

High-throughput

0.407

High

183980

S22A2
Solute carrier family 22 member 2

1

2

High-throughput

0.407

High

190509

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.407

High

1334100

S4A11
Solute carrier family 4 member 11

1

1

High-throughput

0.407

High

1429305

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.407

High

1459035

S4A7
Sodium bicarbonate cotransporter 3

1

1

High-throughput

0.407

High

630195

ACM3
Muscarinic acetylcholine receptor M3

2

0

High-throughput

0.328

High

297377

DYSF
Dysferlin

1

0

High-throughput

0.279

Low

1007899

X3CL1
Fractalkine

1

0

High-throughput

0.279

Low

1234559

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

1458435

HCST
Hematopoietic cell signal transducer

1

0

High-throughput

0.279

Low

1459025

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

168911

PLD2
Phospholipase D2

1

0

High-throughput

0.249

Low

254653

EIF1B
Eukaryotic translation initiation factor 1b

1

0

High-throughput

0.249

Low

295894

FACE1
CAAX prenyl protease 1 homolog

1

0

High-throughput

0.249

Low

362073

AATM
Aspartate aminotransferase, mitochondrial

1

0

High-throughput

0.249

Low

568520

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

717177

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.249

Low

889033

TMEDA
Transmembrane emp24 domain-containing protein 10

1

0

High-throughput

0.249

Low

939834

ATPK
ATP synthase F(0) complex subunit f, mitochondrial

1

0

High-throughput

0.249

Low

944347

TMM33
Transmembrane protein 33

1

0

High-throughput

0.249

Low

963030

CH10
10 kDa heat shock protein, mitochondrial

1

0

High-throughput

0.249

Low

1233549

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.249

Low

1286948

TM11B
Transmembrane protease serine 11B

1

0

High-throughput

0.249

Low

1293186

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1412471

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.249

Low

876445

EAA4
Excitatory amino acid transporter 4

1

0

High-throughput

0.232

Low

1133810

SL9A5
Sodium/hydrogen exchanger 5

1

0

High-throughput

0.232

Low

1335767

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1459031

SC6A5
Sodium- and chloride-dependent glycine transporter 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025