HitPredict

Interactor 1: SAP18 (O00422)
Histone deacetylase complex subunit SAP18 (18 kDa Sin3-associated polypeptide) (2HOR0202) (Cell growth-inhibiting gene 38 protein) (Sin3-associated polypeptide p18)
Gene: SAP18

Interactor 2: ACINU (Q9UKV3)
Apoptotic chromatin condensation inducer in the nucleus (Acinus)
Gene: ACIN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	1.00	0.908

The method score is based on:

Property	Details
Experiments	33961781, 16537548, 22388736, 12665594
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RSB_motif~SAP18
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006397 - mRNA processing and 5 others more... GO:0008380 - RNA splicing GO:0016607 - nuclear speck GO:0043065 - positive regulation of apoptotic process GO:0048025 - negative regulation of mRNA splicing, via spliceosome GO:0061574 - ASAP complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	153
Hs

1	1341

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024