HitPredict

Interactor 1: IF2B3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2 mRNA-binding protein 3) (IMP-3) (IGF-II mRNA-binding protein 3) (KH domain-containing protein overexpressed in cancer) (hKOC) (VICKZ family member 3)
Gene: IGF2BP3

Interactor 2: RAF1 (P04049)
RAF proto-oncogene serine/threonine-protein kinase (EC 2.7.11.1) (Proto-oncogene c-RAF) (cRaf) (Raf-1)
Gene: RAF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36244648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 579 Hs			1 648
+	Hs
		374997 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488818 IF2B1_HUMAN (1-579): 1.24e-135: 408: 72.02		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		374268 PCBP1_HUMAN (277-508): 3.85e-32: 129: 24.14		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374269 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		375177 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374695 FUBP3_HUMAN (189-414): 5.52e-18: 89.3: 14.17		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374171 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		374639 FUBP2_HUMAN (426-567): 1e-12: 73.1: 16.90		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		373604 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		RAF1_HUMAN (1-648): 0: 652: 100.00
+	Hs
		488835 IF2B2_HUMAN (79-477): 8.15e-20: 95.1: 15.50		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		488705 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		488548 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		ARAF_HUMAN (45-646): 4.63e-169: 497: 59.28
+	Hs
		522998 PCBP2_HUMAN (193-484): 7.41e-30: 122: 19.05		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		522960 PABP4_HUMAN (73-346): 8e-14: 76.6: 9.03		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		516342 PABP1_HUMAN (74-346): 1.06e-11: 69.6: 8.30		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45
+	Hs
		522876 PCBP3_HUMAN (134-272): 5.55e-10: 63.3: 20.86		SRC_HUMAN (331-607): 3.01e-106: 333: 33.45