HitPredict

Interactor 1: HUWE1 (Q7Z6Z7)
E3 ubiquitin-protein ligase HUWE1 (EC 2.3.2.26) (ARF-binding protein 1) (ARF-BP1) (HECT, UBA and WWE domain-containing protein 1) (HECT-type E3 ubiquitin transferase HUWE1) (Homologous to E6AP carboxyl terminus homologous protein 9) (HectH9) (Large structure of UREB1) (LASU1) (Mcl-1 ubiquitin ligase E3) (Mule) (Upstream regulatory element-binding protein 1) (URE-B1) (URE-binding protein 1)
Gene: HUWE1

Interactor 2: ANR52 (Q8NB46)
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C (PP6-ARS-C) (Serine/threonine-protein phosphatase 6 regulatory subunit ARS-C) (Ankyrin repeat domain-containing protein 52)
Gene: ANKRD52

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	37167062
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~HECT
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 4374 Hs			1 1076
+	Hs
		1280565 HUWE1_HUMAN (1-4374): 0: 3307: 100.00		ANFY1_HUMAN (110-891): 3.55e-105: 358: 20.11
+	Hs
		1280328 HUWE1_HUMAN (1-4374): 0: 3307: 100.00		ANKH1_HUMAN (862-1073): 1.81e-46: 185: 19.64
+	Hs
		292312 HUWE1_HUMAN (1-4374): 0: 3307: 100.00		TRPA1_HUMAN (589-1017): 7.23e-22: 104: 25.31
+	Hs
		132166 WWP2_HUMAN (3506-4372): 0: 649: 23.78		ANR44_HUMAN (272-1071): 1.96e-172: 533: 24.08
+	Hs
		861588 NEDD4_HUMAN (3130-4372): 0: 612: 21.39		ANK3_HUMAN (1-572): 9.3e-150: 497: 27.43
+	Hs
		1439007 SMUF1_HUMAN (3746-4371): 0: 627: 31.96		ANR50_HUMAN (492-1076): 9.6e-106: 363: 23.17
+	Hs
		1438994 SMUF1_HUMAN (3746-4371): 0: 627: 31.96		ANFY1_HUMAN (110-891): 3.55e-105: 358: 20.11
+	Hs
		131616 WWP2_HUMAN (3506-4372): 0: 649: 23.78		ANR17_HUMAN (842-1071): 1.18e-50: 198: 21.86
+	Dm
		68606 FUTSC_DROME (2724-3916): 2.52e-11: 73.1: 10.24		A8JNM5_DROME (775-1074): 4.36e-52: 203: 16.61