HitPredict

Interactor 1: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Interactor 2: HM20B (Q9P0W2)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (HMG domain-containing protein 2) (HMG domain-containing protein HMGX2) (Sox-like transcriptional factor) (Structural DNA-binding protein BRAF35)
Gene: HMG20B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.735

Property	Details
Experiments	12032298, 34709266, 26186194, 28514442, 15325272, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, biochemical, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 680 Hs			1 317
+	Hs
		1285365 PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00		HM20A_HUMAN (3-313): 3.45e-57: 189: 46.35
+	Hs
		297535 PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00		TOX4_HUMAN (15-201): 2.03e-25: 108: 20.31
+	Hs
		1285342 PF21A_HUMAN (1-680): 2.54e-112: 355: 100.00		SOX7_HUMAN (32-182): 2.11e-24: 103: 20.73
+	Hs
		1332331 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SOX17_HUMAN (5-197): 1.67e-30: 120: 14.72
+	Hs
		1281264 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SMCE1_HUMAN (74-315): 3.79e-29: 117: 21.18
+	Hs
		996961 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91
+	Hs
		818613 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		1311941 TRI33_HUMAN (2-648): 1.4e-85: 293: 16.08		SOX7_HUMAN (32-182): 2.11e-24: 103: 20.73
+	Hs
		170476 TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56		SOX17_HUMAN (5-197): 1.67e-30: 120: 14.72
+	Hs
		170345 TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56		SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91
+	Hs
		170296 TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		170464 TIF1A_HUMAN (2-647): 1.34e-77: 270: 14.56		SOX7_HUMAN (32-182): 2.11e-24: 103: 20.73
+	Hs
		297467 KDM5C_HUMAN (169-655): 3.08e-60: 221: 15.75		TOX4_HUMAN (15-201): 2.03e-25: 108: 20.31
+	Mm
		818732 KDM5B_MOUSE (139-656): 9.66e-59: 217: 14.83		SOX2_MOUSE (37-153): 1.1e-26: 109: 26.50
+	Hs
		331899 BAZ2A_HUMAN (4-648): 1.81e-50: 192: 11.71		NSD2_HUMAN (2-282): 1.75e-30: 123: 13.01
+	Hs
		331813 CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04		NSD2_HUMAN (2-282): 1.75e-30: 123: 13.01
+	Hs
		996673 CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04		SSRP1_HUMAN (31-233): 9.74e-28: 115: 16.91
+	Hs
		818573 BAZ2B_HUMAN (2-648): 3.37e-43: 170: 12.25		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79
+	Hs
		225761 CHD5_HUMAN (255-617): 2.01e-43: 170: 16.79		SOX15_HUMAN (27-236): 5.03e-27: 107: 14.69
+	Hs
		818056 CHD4_HUMAN (324-650): 1.2e-41: 165: 16.04		SOX2_HUMAN (37-153): 1.65e-26: 108: 24.79