Interactor 1: FAF2 (Q96CS3)
FAS-associated factor 2 (UBX domain-containing protein 3B) (UBX domain-containing protein 8)
Gene: FAF2

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 0.60 0.709

The method score is based on:

Property Details
Experiments 22119785, 34079125, 21909096, 22238364, 23665563
Identification Methods affinity chromatography technology, proximity labelling technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0006986 - response to unfolded protein
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0031625 - ubiquitin protein ligase binding
GO:0036503 - ERAD pathway
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 445
Hs

1 251
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024