Protein: LSM5
LSM complex subunit LSM5

Gene: LSM5
Organism: Saccharomyces cerevisiae S288C
Interactions: 117
UniProt ID: P40089

Gene Ontology (top 5):
GO:0000290 - deadenylation-dependent decapping of nuclear-transcribed mRNA
GO:0000398 - mRNA splicing, via spliceosome
GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

818463

LSM1
LSM1-LSM7 complex subunit LSM1

15

16

Small-scale

0.984

High

678686

PAT1
Deadenylation-dependent mRNA-decapping factor PAT1

11

1

Small-scale

0.977

High

818478

LSM3
LSM complex subunit LSM3

9

18

Small-scale

0.972

High

818487

LSM6
LSM complex subunit LSM6

9

6

Small-scale

0.971

High

795875

LSM2
LSM complex subunit LSM2

7

7

Small-scale

0.965

High

818474

LSM7
LSM complex subunit LSM7

6

15

Small-scale

0.934

High

818465

LSM8
LSM2-LSM8 complex subunit LSM8

5

15

Small-scale

0.924

High

818003

LSM4
LSM complex subunit LSM4

4

3

Small-scale

0.909

High

751746

PRP8
Pre-mRNA-splicing factor 8

4

0

Small-scale

0.850

High

818486

SMD2
Small nuclear ribonucleoprotein Sm D2

2

2

High-throughput

0.800

High

818467

SART3
U4/U6 snRNA-associated-splicing factor PRP24

3

0

Small-scale

0.796

High

780181

SN114
Pre-mRNA-splicing factor SNU114

2

0

High-throughput

0.761

High

744118

BRR2
Pre-mRNA-splicing helicase BRR2

6

2

Small-scale

0.722

High

645436

XRN1
5'-3' exoribonuclease 1

5

0

High-throughput

0.684

High

818455

RUXG
Small nuclear ribonucleoprotein G

1

14

High-throughput

0.665

High

625016

PRP6
Pre-mRNA-splicing factor 6

2

2

High-throughput

0.621

High

627852

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

2

2

High-throughput

0.621

High

817115

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

2

High-throughput

0.618

High

818481

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

1

1

High-throughput

0.618

High

818453

LSM5
LSM complex subunit LSM5

1

0

Small-scale

0.589

High

818500

DCP1
mRNA-decapping enzyme subunit 1

2

0

Small-scale

0.576

High

721624

RENT1
ATP-dependent helicase NAM7

2

0

Small-scale

0.561

High

737730

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

0

High-throughput

0.549

High

670188

MRM1
rRNA methyltransferase 1, mitochondrial

1

1

High-throughput

0.508

High

818492

TRM3
tRNA

1

1

High-throughput

0.508

High

149211

FOB1
DNA replication fork-blocking protein FOB1

1

0

High-throughput

0.486

High

438305

NOT3
General negative regulator of transcription subunit 3

1

0

High-throughput

0.486

High

644933

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

0

High-throughput

0.486

High

818461

YFG6
Y' element ATP-dependent helicase YFL066C

1

0

High-throughput

0.486

High

818498

PTPA2
Serine/threonine-protein phosphatase 2A activator 2

1

0

High-throughput

0.486

High

818496

CLF1
Pre-mRNA-splicing factor CLF1

1

3

Small-scale

0.479

High

818497

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

1

1

Small-scale

0.479

High

512469

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.460

High

584235

MS116
ATP-dependent RNA helicase MSS116, mitochondrial

1

0

High-throughput

0.458

High

677418

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.458

High

707228

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

743763

RML2
Large ribosomal subunit protein uL2m

1

0

High-throughput

0.458

High

747884

SMY2
Protein SMY2

1

0

Small-scale

0.458

High

783925

RM07
Large ribosomal subunit protein uL5m

1

0

High-throughput

0.458

High

812047

DHH1
ATP-dependent RNA helicase DHH1

1

0

High-throughput

0.458

High

818462

SCD6
Protein SCD6

1

0

Small-scale

0.458

High

818477

APJ1
J domain-containing protein APJ1

1

0

High-throughput

0.458

High

818482

CWC21
Pre-mRNA-splicing factor CWC21

1

0

Small-scale

0.458

High

818483

RM34
Large ribosomal subunit protein bL34m

1

0

High-throughput

0.458

High

818484

RM01
Large ribosomal subunit protein uL1m

1

0

High-throughput

0.458

High

818489

MHR1
Large ribosomal subunit protein mL67

1

0

High-throughput

0.458

High

818494

NMD4
Nonsense-mediated decay protein 4

1

0

Small-scale

0.458

High

818495

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

545051

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.445

High

818454

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

792819

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.438

High

811211

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

742863

HSP79
Heat shock protein homolog SSE2

1

0

High-throughput

0.426

High

818476

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.269

Low

556572

STE6
Alpha-factor-transporting ATPase

1

0

High-throughput

0.265

Low

575343

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.265

Low

672495

SYNM
Asparagine--tRNA ligase, mitochondrial

1

0

High-throughput

0.265

Low

790203

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.265

Low

803338

YHA8
Uncharacterized transporter YHL008C

1

0

High-throughput

0.265

Low

815403

RS26B
Small ribosomal subunit protein eS26B

1

0

High-throughput

0.265

Low

818458

ATC7
Phospholipid-transporting ATPase NEO1

1

0

High-throughput

0.265

Low

818460

YG4I
Uncharacterized GTP-binding protein YGR210C

1

0

High-throughput

0.265

Low

818464

ALY2
Arrestin-related trafficking adapter 3

1

0

High-throughput

0.265

Low

818466

IML1
Vacuolar membrane-associated protein IML1

1

0

High-throughput

0.265

Low

818488

GDE
Glycogen debranching enzyme

1

0

High-throughput

0.265

Low

818493

GNT1
Glucose N-acetyltransferase 1

1

0

High-throughput

0.265

Low

554613

RM02
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.249

Low

569499

RM31
Large ribosomal subunit protein mL60

1

0

High-throughput

0.249

Low

628160

RM33
Large ribosomal subunit protein uL30m

1

0

High-throughput

0.249

Low

647918

RM08
Large ribosomal subunit protein bL17m

1

0

High-throughput

0.249

Low

647987

RM20
Large ribosomal subunit protein mL58

1

0

High-throughput

0.249

Low

657449

RM25
Large ribosomal subunit protein mL59

1

0

High-throughput

0.249

Low

672543

RM32
Large ribosomal subunit protein bL32m

1

0

High-throughput

0.249

Low

678184

IMG1
Large ribosomal subunit protein bL19m

1

0

High-throughput

0.249

Low

678599

IMG2
Large ribosomal subunit protein mL49

1

0

High-throughput

0.249

Low

725726

RM09
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.249

Low

736262

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.249

Low

736345

RM49
Large ribosomal subunit protein mL61

1

0

High-throughput

0.249

Low

747229

RM06
Large ribosomal subunit protein uL6m

1

0

High-throughput

0.249

Low

758004

PXA2
Peroxisomal long-chain fatty acid import protein 1

1

0

High-throughput

0.249

Low

778215

RM38
Large ribosomal subunit protein uL14m

1

0

High-throughput

0.249

Low

783791

RM03
Large ribosomal subunit protein mL44

1

0

High-throughput

0.249

Low

783857

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.249

Low

783983

RM10
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.249

Low

784048

RM11
Large ribosomal subunit protein uL10m

1

0

High-throughput

0.249

Low

784101

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.249

Low

784163

RM24
Large ribosomal subunit protein bL28m

1

0

High-throughput

0.249

Low

784213

RM27
Large ribosomal subunit protein mL41

1

0

High-throughput

0.249

Low

784254

RM28
Large ribosomal subunit protein mL40

1

0

High-throughput

0.249

Low

784315

RM17
Large ribosomal subunit protein mL46

1

0

High-throughput

0.249

Low

784381

RM36
Large ribosomal subunit protein bL31m

1

0

High-throughput

0.249

Low

784424

RM37
Large ribosomal subunit protein mL54

1

0

High-throughput

0.249

Low

784452

RM39
Large ribosomal subunit protein bL33m

1

0

High-throughput

0.249

Low

784485

RM40
Large ribosomal subunit protein uL24m

1

0

High-throughput

0.249

Low

792612

RM16
Large ribosomal subunit protein uL16m

1

0

High-throughput

0.249

Low

812344

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

818457

MLP2
Protein MLP2

1

0

High-throughput

0.249

Low

818459

RN49
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.249

Low

818468

RL4P
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

818469

MNP1
Large ribosomal subunit protein bL12m

1

0

High-throughput

0.249

Low

818470

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

818471

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.249

Low

818472

RM19
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

818473

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.249

Low

818475

RN35
Large ribosomal subunit protein bL35m

1

0

High-throughput

0.249

Low

818479

RM13
Large ribosomal subunit protein mL50

1

0

High-throughput

0.249

Low

818480

ATP25
ATPase synthesis protein 25, mitochondrial

1

0

High-throughput

0.249

Low

818485

RM51
Large ribosomal subunit protein mL43

1

0

High-throughput

0.249

Low

818490

RM35
Large ribosomal subunit protein mL38

1

0

High-throughput

0.249

Low

818491

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.249

Low

818499

RM23
Large ribosomal subunit protein uL13m

1

0

High-throughput

0.249

Low

510534

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

579483

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

752314

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low

779541

LHS1
Heat shock protein 70 homolog LHS1

1

0

High-throughput

0.232

Low

818456

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025