HitPredict

Interactor 1: ZFHX4 (Q86UP3)
Zinc finger homeobox protein 4 (Zinc finger homeodomain protein 4) (ZFH-4)
Gene: ZFHX4

Interactor 2: VSX1 (Q9NZR4)
Visual system homeobox 1 (Homeodomain protein RINX) (Retinal inner nuclear layer homeobox protein) (Transcription factor VSX1)
Gene: VSX1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Homeodomain~Homeodomain
Common GO terms	GO:0000785 - chromatin GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0005634 - nucleus
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 3567 Hs			1 365
+	Hs
		895746 ZFHX4_HUMAN (1-3567): 0: 1743: 100.00		LHX2_HUMAN (78-301): 7.68e-35: 133: 24.11
+	Hs
		942447 ZFHX4_HUMAN (1-3567): 0: 1743: 100.00		GSC_HUMAN (1-261): 2.17e-35: 131: 26.34
+	Hs
		685253 ZFHX4_HUMAN (1-3567): 0: 1743: 100.00		PAX6_HUMAN (116-362): 3.03e-32: 127: 24.61
+	Hs
		662245 ZFHX4_HUMAN (1-3567): 0: 1743: 100.00		PAX7_HUMAN (147-358): 1.68e-30: 123: 28.32
+	Hs
		1178667 ZFHX4_HUMAN (1-3567): 0: 1743: 100.00		ISX_HUMAN (154-224): 8.81e-19: 86.3: 59.16
+	Hs
		1155995 ZFHX3_HUMAN (1888-3272): 3.76e-14: 81.9: 11.77		VSX1_HUMAN (1-365): 5.29e-61: 201: 100.00
+	Dm
		84261 B6VQ99_DROME (1352-1621): 1.08e-28: 123: 16.73		Q9XZU0_DROME (156-345): 6.86e-32: 124: 26.96
+	Dm
		84252 B6VQ99_DROME (1352-1621): 1.08e-28: 123: 16.73		Q8T0V5_DROME (156-345): 1.47e-31: 123: 26.96
+	Dm
		1465686 Q9V472_DROME (2494-2617): 2.83e-10: 68.2: 33.07		X2JDS9_DROME (127-343): 1.41e-43: 161: 45.05
+	Hs
		895721 ZFHX3_HUMAN (1888-3272): 3.76e-14: 81.9: 11.77		LHX2_HUMAN (78-301): 7.68e-35: 133: 24.11
+	Hs
		942436 ZFHX3_HUMAN (1888-3272): 3.76e-14: 81.9: 11.77		GSC_HUMAN (1-261): 2.17e-35: 131: 26.34
+	Hs
		685205 ZFHX3_HUMAN (1888-3272): 3.76e-14: 81.9: 11.77		PAX6_HUMAN (116-362): 3.03e-32: 127: 24.61
+	Dm
		68399 Q9VDN4_DROME (1352-1573): 7.1e-09: 63.5: 25.68		A8DYR8_DROME (93-225): 6.08e-38: 142: 39.10
+	Dm
		1465681 Q9V472_DROME (2494-2617): 2.83e-10: 68.2: 33.07		Q9W2P8_DROME (131-273): 5.09e-36: 137: 38.96
+	Hs
		662230 ZFHX3_HUMAN (1888-3272): 3.76e-14: 81.9: 11.77		PAX7_HUMAN (147-358): 1.68e-30: 123: 28.32
+	Dm
		1465684 Q9V472_DROME (2494-2617): 2.83e-10: 68.2: 33.07		Q9W4B3_DROME (135-343): 6.71e-31: 125: 46.89
+	Dm
		1458132 Q9VDN4_DROME (1352-1573): 7.1e-09: 63.5: 25.68		Q9U984_DROME (143-235): 3.21e-31: 117: 26.88
+	Dm
		1470866 Q9VDN4_DROME (1352-1573): 7.1e-09: 63.5: 25.68		Q9VCY0_DROME (143-235): 1.14e-30: 116: 27.96