Protein: NPHP1
Nephrocystin-1 (Juvenile nephronophthisis 1 protein)

Gene: NPHP1
Organism: Homo sapiens
Interactions: 99
UniProt ID: O15259

Gene Ontology (top 5):
GO:0005198 - structural molecule activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005856 - cytoskeleton
GO:0005911 - cell-cell junction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

173569

BCAR1
Breast cancer anti-estrogen resistance protein 1

3

3

Small-scale

0.871

High

173575

ACK1
Activated CDC42 kinase 1

2

1

Small-scale

0.807

High

173582

FAK2
Protein-tyrosine kinase 2-beta

2

0

Small-scale

0.765

High

173543

NPHP4
Nephrocystin-4

6

4

Small-scale

0.735

High

173614

UBQL4
Ubiquilin-4

1

2

High-throughput

0.698

High

173589

FTM
Protein fantom

3

3

High-throughput

0.667

High

173599

RPGR
X-linked retinitis pigmentosa GTPase regulator

3

1

Small-scale

0.667

High

173597

AHI1
Jouberin

1

1

Small-scale

0.665

High

173579

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

2

2

Small-scale

0.646

High

173602

DNJC7
DnaJ homolog subfamily C member 7

2

1

High-throughput

0.628

High

173539

NPHP1
Nephrocystin-1

1

1

Small-scale

0.618

High

173587

SH319
SH3 domain-containing protein 19

1

1

High-throughput

0.618

High

173591

DNMBP
Dynamin-binding protein

1

1

High-throughput

0.618

High

173628

INVS
Inversin

1

4

Small-scale

0.618

High

173623

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

0

Small-scale

0.614

High

173565

DYN2
Dynamin-2

1

0

High-throughput

0.586

High

173577

FLII
Protein flightless-1 homolog

1

0

High-throughput

0.586

High

173612

TENS1
Tensin-1

1

0

Small-scale

0.586

High

173633

SNX9
Sorting nexin-9

1

0

High-throughput

0.586

High

173601

TM237
Transmembrane protein 237

2

0

High-throughput

0.585

High

173570

PKD1
Polycystin-1

1

0

Small-scale

0.578

High

173556

FLNA
Filamin-A

1

2

Small-scale

0.552

High

173555

FILA
Filaggrin

1

1

High-throughput

0.536

High

173568

TTC3
E3 ubiquitin-protein ligase TTC3

1

2

High-throughput

0.536

High

173590

ZN746
Zinc finger protein 746

1

1

High-throughput

0.536

High

173606

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

Small-scale

0.493

High

173619

ZN282
Zinc finger protein 282

1

1

High-throughput

0.489

High

173544

FLNB
Filamin-B

1

2

Small-scale

0.481

High

173630

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

130645

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

173547

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.479

High

173549

TBB5
Tubulin beta chain

1

2

Small-scale

0.479

High

173594

NPHP3
Nephrocystin-3

1

1

Small-scale

0.479

High

173607

UN45A
Protein unc-45 homolog A

1

2

High-throughput

0.479

High

173608

RPAP3
RNA polymerase II-associated protein 3

1

1

High-throughput

0.479

High

173626

CE164
Centrosomal protein of 164 kDa

1

3

Small-scale

0.479

High

173627

RUVB1
RuvB-like 1

1

1

Small-scale

0.479

High

173632

HYOU1
Hypoxia up-regulated protein 1

1

2

High-throughput

0.479

High

64626

RHG32
Rho GTPase-activating protein 32

1

0

Small-scale

0.460

High

173541

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

173546

RMP
Unconventional prefoldin RPB5 interactor 1

1

0

High-throughput

0.458

High

173548

ECD
Protein ecdysoneless homolog

1

0

High-throughput

0.458

High

173550

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

0

High-throughput

0.458

High

173551

HXK1
Hexokinase-1

1

0

High-throughput

0.458

High

173552

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

173553

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

0

High-throughput

0.458

High

173554

RAB6A
Ras-related protein Rab-6A

1

0

High-throughput

0.458

High

173558

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

173560

ERD22
ER lumen protein-retaining receptor 2

1

0

High-throughput

0.458

High

173561

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.458

High

173562

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.458

High

173563

PRC2A
Protein PRRC2A

1

0

High-throughput

0.458

High

173564

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

0

High-throughput

0.458

High

173566

PSMD7
26S proteasome non-ATPase regulatory subunit 7

1

0

High-throughput

0.458

High

173567

COPA
Coatomer subunit alpha

1

0

High-throughput

0.458

High

173571

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.458

High

173572

SRSF2
Serine/arginine-rich splicing factor 2

1

0

High-throughput

0.458

High

173573

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

0

High-throughput

0.458

High

173576

FCHO2
F-BAR domain only protein 2

1

0

High-throughput

0.458

High

173578

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.458

High

173580

TTL12
Tubulin--tyrosine ligase-like protein 12

1

0

High-throughput

0.458

High

173581

DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

0

High-throughput

0.458

High

173583

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.458

High

173584

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.458

High

173586

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.458

High

173588

CE170
Centrosomal protein of 170 kDa

1

0

High-throughput

0.458

High

173592

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

1

0

High-throughput

0.458

High

173595

NUDC3
NudC domain-containing protein 3

1

0

High-throughput

0.458

High

173596

PHAR4
Phosphatase and actin regulator 4

1

0

High-throughput

0.458

High

173598

TM256
Transmembrane protein 256

1

0

High-throughput

0.458

High

173609

BCAS3
BCAS3 microtubule associated cell migration factor

1

0

High-throughput

0.458

High

173610

WDR41
WD repeat-containing protein 41

1

0

High-throughput

0.458

High

173611

CYBP
Calcyclin-binding protein

1

0

High-throughput

0.458

High

173613

TM9S3
Transmembrane 9 superfamily member 3

1

0

High-throughput

0.458

High

173615

PDRG1
p53 and DNA damage-regulated protein 1

1

0

High-throughput

0.458

High

173616

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

173618

UXT
Protein UXT

1

0

High-throughput

0.458

High

173620

SEC63
Translocation protein SEC63 homolog

1

0

High-throughput

0.458

High

173621

BI2L1
BAR/IMD domain-containing adapter protein 2-like 1

1

0

High-throughput

0.458

High

173622

XPO7
Exportin-7

1

0

High-throughput

0.458

High

173624

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

0

High-throughput

0.458

High

173625

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.458

High

173629

PHOCN
MOB-like protein phocein

1

0

High-throughput

0.458

High

173634

S23IP
SEC23-interacting protein

1

0

High-throughput

0.458

High

173540

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

1

2

Small-scale

0.457

High

173605

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

2

Small-scale

0.457

High

173617

SPAT7
Spermatogenesis-associated protein 7

1

1

Small-scale

0.457

High

173559

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

1

High-throughput

0.437

High

173593

CE128
Centrosomal protein of 128 kDa

1

1

High-throughput

0.437

High

173574

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

1

0

Small-scale

0.391

High

173557

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

0

High-throughput

0.328

High

173585

TIGD5
Tigger transposable element-derived protein 5

1

0

High-throughput

0.279

Low

173542

IDH3B
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

173545

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.249

Low

173600

DAA10
Dynein axonemal assembly factor 10

1

0

High-throughput

0.249

Low

173603

GPTC1
G patch domain-containing protein 1

1

0

High-throughput

0.249

Low

173604

WDR83
WD repeat domain-containing protein 83

1

0

High-throughput

0.249

Low

173631

CHTOP
Chromatin target of PRMT1 protein

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024