HitPredict

Interactor 1: LRCH3 (Q96II8)
DISP complex protein LRCH3 (Leucine-rich repeat and calponin homology domain-containing protein 3)
Gene: LRCH3

Interactor 2: LRCH1 (Q9Y2L9)
Leucine-rich repeat and calponin homology domain-containing protein 1 (Calponin homology domain-containing protein 1) (Neuronal protein 81) (NP81)
Gene: LRCH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	1.00	0.871

Property	Details
Experiments	33961781, 28514442, 24255178
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	CH~CH, LRR_8~LRR_8
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 728
+	Hs
		1073347 LRCH3_HUMAN (14-777): 1.96e-178: 532: 100.00		RSU1_HUMAN (60-322): 6.55e-54: 188: 29.21
+	Hs
		264516 LRCH3_HUMAN (14-777): 1.96e-178: 532: 100.00		LRCH4_HUMAN (5-187): 2.31e-23: 107: 17.35
+	Hs
		1138579 LRCH3_HUMAN (14-777): 1.96e-178: 532: 100.00		LRCH2_HUMAN (6-170): 2e-19: 95.2: 14.69
+	At
		221778 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		BAME1_ARATH (97-658): 2.7e-63: 230: 14.76
+	At
		1258435 MIK2_ARATH (3-582): 1.61e-87: 300: 13.45		BAME2_ARATH (3-412): 3.22e-43: 170: 13.86
+	At
		221761 ERECT_ARATH (22-322): 2.59e-57: 213: 24.84		BAME1_ARATH (97-658): 2.7e-63: 230: 14.76
+	At
		1324076 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		MIK1_ARATH (192-625): 1e-32: 137: 10.30
+	At
		1338953 Y1571_ARATH (6-590): 1.82e-85: 295: 15.09		BRL2_ARATH (5-280): 2.02e-23: 108: 19.45
+	At
		1167629 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		ERL2_ARATH (338-676): 9.36e-29: 125: 9.48
+	Dm
		1181694 SCRIB_DROME (41-512): 1.1e-61: 228: 16.12		SCRIB_DROME (23-226): 1.12e-36: 150: 26.09
+	At
		85369 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		ERL1_ARATH (5-222): 9.75e-24: 109: 18.75
+	At
		1324067 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		FLS2_ARATH (368-626): 1.57e-22: 105: 7.72
+	At
		1114705 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		ERECT_ARATH (337-549): 4.48e-22: 104: 9.86
+	At
		99021 FLS2_ARATH (8-617): 2.28e-75: 267: 14.38		RGI4_ARATH (450-705): 1.67e-16: 86.3: 14.61
+	At
		1114685 ERECT_ARATH (22-322): 2.59e-57: 213: 24.84		ERL2_ARATH (338-676): 9.36e-29: 125: 9.48
+	At
		84461 SKM1_ARATH (5-419): 7.13e-61: 223: 18.79		GSO1_ARATH (353-647): 1.64e-22: 105: 11.51
+	At
		85352 ERECT_ARATH (22-322): 2.59e-57: 213: 24.84		ERL1_ARATH (5-222): 9.75e-24: 109: 18.75
+	At
		84466 ERECT_ARATH (22-322): 2.59e-57: 213: 24.84		GSO1_ARATH (353-647): 1.64e-22: 105: 11.51
+	At
		1114682 ERECT_ARATH (22-322): 2.59e-57: 213: 24.84		ERECT_ARATH (337-549): 4.48e-22: 104: 9.86
+	At
		84593 ERECT_ARATH (22-322): 2.59e-57: 213: 24.84		RGI3_ARATH (2-163): 5.67e-13: 74.7: 14.11