HitPredict

Interactor 1: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28292929
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	zf-RING_2~zf-RING_2
Common GO terms	GO:0008270 - zinc ion binding GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 1208 Hs			1 154
+	Zm
		78684 B4FHZ7_MAIZE (1112-1206): 3.15e-23: 104: 27.08		B4FHZ7_MAIZE (6-153): 1.74e-27: 106: 21.33
+	Hs
		220508 RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90		RNF13_HUMAN (77-146): 8.83e-27: 104: 33.80
+	Hs
		1294202 GOLI_HUMAN (1107-1194): 1.09e-21: 101: 23.33		GOLI_HUMAN (64-146): 5.88e-26: 103: 25.30
+	Hs
		1294211 GOLI_HUMAN (1107-1194): 1.09e-21: 101: 23.33		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		1334464 RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		1334478 RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90		RN128_HUMAN (57-153): 3.1e-25: 101: 25.77
+	Hs
		1334490 RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90		RN133_HUMAN (79-147): 1.65e-25: 101: 31.88
+	Hs
		1352293 RN128_HUMAN (1112-1206): 2.55e-21: 100: 26.73		RN128_HUMAN (57-153): 3.1e-25: 101: 25.77
+	Hs
		1287365 GOLI_HUMAN (1107-1194): 1.09e-21: 101: 23.33		SYVN1_HUMAN (72-152): 1.78e-24: 99: 28.40
+	Hs
		1287379 RN149_HUMAN (1134-1206): 1.2e-21: 101: 32.90		SYVN1_HUMAN (72-152): 1.78e-24: 99: 28.40
+	Mm
		1353937 MYH9_MOUSE (504-985): 1.77e-19: 97.4: 8.11		SYVN1_MOUSE (72-152): 4.41e-24: 98.8: 28.40
+	Hs
		1450914 MYH2_HUMAN (528-1060): 3.26e-17: 90: 8.71		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1287358 SYVN1_HUMAN (1108-1192): 8.86e-15: 80.9: 32.58		SYVN1_HUMAN (72-152): 1.78e-24: 99: 28.40
+	Mm
		1424218 PLEC_MOUSE (612-1080): 6.92e-14: 79.2: 9.26		SYVN1_MOUSE (72-152): 4.41e-24: 98.8: 28.40
+	Hs
		563035 MYH6_HUMAN (501-908): 9.14e-13: 75.4: 10.17		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29