HitPredict

Interactor 1: TRAF5 (O00463)
TNF receptor-associated factor 5 (RING finger protein 84)
Gene: TRAF5

Interactor 2: TNR4 (P43489)
Tumor necrosis factor receptor superfamily member 4 (ACT35 antigen) (OX40L receptor) (TAX transcriptionally-activated glycoprotein 1 receptor) (CD antigen CD134)
Gene: TNFRSF4

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.50	0.579

Property	Details
Experiments	9488716, 15941918
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 557 Hs			1 277
+	Mm
		192584 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR11_MOUSE (6-181): 1.51e-42: 155: 27.59
+	Mm
		812913 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR4_MOUSE (23-277): 8.81e-65: 205: 62.26
+	Hs
		129607 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR11_HUMAN (28-181): 6.78e-37: 139: 26.40
+	Hs
		129532 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR5_HUMAN (9-175): 1.09e-38: 138: 25.52
+	Hs
		129526 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR16_HUMAN (31-244): 1.06e-36: 136: 25.40
+	Hs
		129536 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR3_HUMAN (11-180): 1.07e-35: 134: 22.86
+	Hs
		129584 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR14_HUMAN (6-165): 2.79e-31: 119: 23.53
+	Mm
		936208 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR14_MOUSE (12-169): 4.66e-33: 123: 28.65
+	Mm
		838552 TRAF5_MOUSE (1-557): 4.13e-146: 434: 79.57		TNR3_MOUSE (32-194): 1.62e-31: 122: 25.39
+	Hs
		129553 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR9_HUMAN (43-186): 2.65e-27: 107: 24.84
+	Hs
		129533 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		CD27_HUMAN (12-144): 8.02e-25: 101: 27.94
+	Hs
		129599 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR19_HUMAN (7-140): 7.43e-23: 98.7: 20.98
+	Mm
		192587 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR11_MOUSE (6-181): 1.51e-42: 155: 27.59
+	Hs
		129534 TRAF5_HUMAN (1-557): 1.31e-149: 443: 100.00		TNR8_HUMAN (30-203): 1.02e-19: 90.3: 21.62
+	Hs
		591320 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1B_HUMAN (18-248): 6.04e-44: 156: 21.85
+	Mm
		648958 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR5_MOUSE (9-175): 3.3e-38: 137: 23.44
+	Hs
		436620 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR16_HUMAN (31-244): 1.06e-36: 136: 25.40
+	Mm
		838553 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR3_MOUSE (32-194): 1.62e-31: 122: 25.39
+	Hs
		584394 TRAF3_HUMAN (4-556): 6.49e-122: 372: 40.99		TNR1A_HUMAN (14-198): 1.94e-33: 128: 18.65
+	Mm
		591448 TRAF3_MOUSE (2-556): 1.12e-124: 379: 41.09		TNR9_MOUSE (43-183): 5.72e-22: 93.7: 24.52