HitPredict

Interactor 1: MD12L (Q86YW9)
Mediator of RNA polymerase II transcription subunit 12-like protein (Mediator complex subunit 12-like protein) (Thyroid hormone receptor-associated-like protein) (Trinucleotide repeat-containing gene 11 protein-like)
Gene: MED12L

Interactor 2: MED17 (Q9NVC6)
Mediator of RNA polymerase II transcription subunit 17 (Activator-recruited cofactor 77 kDa component) (ARC77) (Cofactor required for Sp1 transcriptional activation subunit 6) (CRSP complex subunit 6) (Mediator complex subunit 17) (Thyroid hormone receptor-associated protein complex 80 kDa component) (Trap80) (Transcriptional coactivator CRSP77) (Vitamin D3 receptor-interacting protein complex 80 kDa component) (DRIP80)
Gene: MED17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0016592 - mediator complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 2145 Hs			1 651
+	Hs
		1372204 MED12_HUMAN (1-2041): 0: 2270: 58.81		MED17_HUMAN (1-651): 0: 1032: 100.00
+	Dm
		1472616 MED12_DROME (10-207): 2.57e-71: 269: 51.01		MED17_DROME (6-647): 0: 849: 42.19