Protein: MED17
Mediator of RNA polymerase II transcription subunit 17 (Mediator complex subunit 17) (dMED17) (dTRAP80)

Gene: MED17
Organism: Drosophila melanogaster
Interactions: 72
UniProt ID: Q9VEC1

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0005721 - pericentric heterochromatin
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1465333

MED22
Mediator of RNA polymerase II transcription subunit 22

4

1

Small-scale

0.683

High

1321559

MED6
Mediator of RNA polymerase II transcription subunit 6

3

1

Small-scale

0.664

High

1019291

MED20
Mediator of RNA polymerase II transcription subunit 20

3

1

Small-scale

0.651

High

1472615

MED11
Mediator of RNA polymerase II transcription subunit 11

3

1

Small-scale

0.650

High

1472621

MED30
Mediator of RNA polymerase II transcription subunit 30

3

1

Small-scale

0.650

High

1269617

MED13
Mediator of RNA polymerase II transcription subunit 13

3

2

Small-scale

0.633

High

1472622

MED14
Mediator of RNA polymerase II transcription subunit 14

3

2

Small-scale

0.633

High

56992

A1ZAK9
P-element somatic inhibitor, isoform A

2

1

Small-scale

0.584

High

1022337

DIF
Dorsal-related immunity factor Dif

2

2

Small-scale

0.584

High

1465848

MED26
Mediator of RNA polymerase II transcription subunit 26

2

1

Small-scale

0.584

High

616605

ARM
Armadillo segment polarity protein

2

0

Small-scale

0.582

High

653090

HSF
Heat shock factor protein

2

0

Small-scale

0.582

High

58496

MED8
Mediator of RNA polymerase II transcription subunit 8

2

1

High-throughput

0.571

High

674045

BRM
ATP-dependent helicase brm

2

1

High-throughput

0.571

High

1267060

MED29
Mediator of RNA polymerase II transcription subunit 29

2

1

High-throughput

0.571

High

1302888

MED31
Mediator of RNA polymerase II transcription subunit 31

2

1

High-throughput

0.571

High

1377780

EBI
F-box-like/WD repeat-containing protein ebi

2

1

High-throughput

0.571

High

1427982

MED10
Mediator of RNA polymerase II transcription subunit 10

2

1

High-throughput

0.571

High

1428094

MED7
Mediator of RNA polymerase II transcription subunit 7

2

1

High-throughput

0.571

High

1471827

MED25
Mediator of RNA polymerase II transcription subunit 25

2

1

High-throughput

0.571

High

1472602

Q9VF03
Brahma associated protein 155 kDa

2

2

High-throughput

0.571

High

1472606

MED27
Mediator of RNA polymerase II transcription subunit 27

2

1

High-throughput

0.571

High

1472609

MED4
Mediator of RNA polymerase II transcription subunit 4

2

1

High-throughput

0.571

High

1472610

MED24
Mediator of RNA polymerase II transcription subunit 24

2

1

High-throughput

0.571

High

1472611

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

3

High-throughput

0.571

High

1472612

CDK8
Cyclin-dependent kinase 8

2

4

High-throughput

0.571

High

1472617

BAP60
Brahma-associated protein of 60 kDa

2

1

High-throughput

0.571

High

1472623

MED23
Mediator of RNA polymerase II transcription subunit 23

2

2

High-throughput

0.571

High

1472624

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

High-throughput

0.571

High

1472626

MED18
Mediator of RNA polymerase II transcription subunit 18

2

1

High-throughput

0.571

High

451861

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

2

0

Small-scale

0.559

High

900660

DSH
Segment polarity protein dishevelled

2

0

High-throughput

0.547

High

1171893

Q24090
GH08712p

2

0

High-throughput

0.547

High

1261412

Q7JQT8
LD41464p

2

0

High-throughput

0.547

High

1303617

OSA
Trithorax group protein osa

2

0

High-throughput

0.547

High

1306409

INDRA
Zinc finger protein indra

2

0

High-throughput

0.547

High

1472578

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

2

0

High-throughput

0.547

High

1472603

Q9VL29
GEO11246p1

2

0

High-throughput

0.547

High

1469496

MED28
Mediator of RNA polymerase II transcription subunit 28

1

1

Small-scale

0.536

High

53586

A1Z813
Secretory 24AB, isoform A

2

1

High-throughput

0.521

High

1346421

MESD
LDLR chaperone boca

2

1

High-throughput

0.521

High

1440681

LAR4
La-related protein Larp4B

2

1

High-throughput

0.521

High

1472605

Q9VNF8
Protein transport protein SEC23

2

1

High-throughput

0.521

High

1472613

Q9VUB7
PAX-interacting protein 1

2

1

High-throughput

0.521

High

426759

HP1
Heterochromatin protein 1

1

1

Small-scale

0.479

High

583390

DORS
Embryonic polarity protein dorsal

1

2

Small-scale

0.479

High

628541

USP
Protein ultraspiracle

1

4

Small-scale

0.479

High

1472627

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.479

High

1305332

Q8IQC5
IP15679p

1

0

Small-scale

0.458

High

1472608

Q9VR42
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.458

High

56949

A1ZAK7
LD35640p

1

1

High-throughput

0.445

High

1343899

Q8SXP8
TAR DNA-binding protein 43

1

1

High-throughput

0.445

High

1472607

MED1
Mediator of RNA polymerase II transcription subunit 1

1

1

High-throughput

0.445

High

1472614

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.445

High

1472616

MED12
Mediator of RNA polymerase II transcription subunit 12

1

2

High-throughput

0.445

High

84981

B7Z126
non-specific serine/threonine protein kinase

1

0

High-throughput

0.426

High

197471

O18353
CHIP

1

0

High-throughput

0.426

High

1263893

Q7K012
Brahma associated protein 55kD

1

0

High-throughput

0.426

High

1409390

Q9BIW6
Brahma-associated protein 111kD

1

0

High-throughput

0.426

High

1472618

Q9VYK0
Smrter, isoform D

1

0

High-throughput

0.426

High

1472625

Q9W3G1
Uncharacterized protein, isoform A

1

0

High-throughput

0.426

High

1321511

ENC
Protein encore

2

0

High-throughput

0.298

High

1378915

Q960F7
SD03629p

2

0

High-throughput

0.298

High

1472620

Q9W0L7
ubiquitinyl hydrolase 1

2

0

High-throughput

0.298

High

54215

A1Z8B1
Uncharacterized protein, isoform A

1

0

High-throughput

0.265

Low

1472604

Q9VMU7
FI16614p1

1

0

High-throughput

0.249

Low

1472619

Q9VYZ8
GEO08286p1

1

0

High-throughput

0.249

Low

84722

UNR
RNA-binding protein Unr

1

0

High-throughput

0.232

Low

1069930

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.232

Low

1345932

Q8T4A8
AT07769p

1

0

High-throughput

0.232

Low

1346017

ENA
Protein enabled

1

0

High-throughput

0.232

Low

1378336

Q95TT5
LD24616p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025