Interactor 1: UBP47 (Q96K76)
Ubiquitin carboxyl-terminal hydrolase 47 (EC 3.4.19.12) (Deubiquitinating enzyme 47) (Ubiquitin thioesterase 47) (Ubiquitin-specific-processing protease 47)
Gene: USP47

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.969

The method score is based on:

Property Details
Experiments 25332235, 25900982, 25515538, 28514442, 33961781, 19615732, 19966869, 22017875, 25609649
Identification Methods affinity chromatography technology, proximity labelling technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains UCH~WD40
Common GO terms GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0019005 - SCF ubiquitin ligase complex
GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 1375
Hs

1 542
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024