Protein: ASPM
Abnormal spindle-like microcephaly-associated protein (Abnormal spindle protein homolog) (Asp homolog)

Gene: ASPM
Organism: Homo sapiens
Interactions: 179
UniProt ID: Q8IZT6

Gene Ontology (top 5):
GO:0001764 - neuron migration
GO:0002052 - positive regulation of neuroblast proliferation
GO:0005516 - calmodulin binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

533996

MLRV
Myosin regulatory light chain 2, ventricular/cardiac muscle isoform

2

20

High-throughput

0.811

High

51453

FSD2
Fibronectin type III and SPRY domain-containing protein 2

2

20

High-throughput

0.776

High

1125001

RCN2
Reticulocalbin-2

2

20

Small-scale

0.694

High

870142

LIMS1
LIM and senescent cell antigen-like-containing domain protein 1

1

15

High-throughput

0.691

High

828400

PEX19
Peroxisomal biogenesis factor 19

3

4

High-throughput

0.667

High

1292783

SKAP1
Src kinase-associated phosphoprotein 1

3

20

High-throughput

0.667

High

1316856

DTBP1
Dysbindin

3

4

High-throughput

0.667

High

1316844

FOXJ1
Forkhead box protein J1

3

5

High-throughput

0.662

High

1316851

MOAP1
Modulator of apoptosis 1

3

17

High-throughput

0.662

High

1316865

GCP5
Gamma-tubulin complex component 5

3

4

Small-scale

0.662

High

1316867

FEZ1
Fasciculation and elongation protein zeta-1

3

1

High-throughput

0.662

High

1316871

LZTS2
Leucine zipper putative tumor suppressor 2

3

20

High-throughput

0.662

High

1029337

SET
Protein SET

3

6

High-throughput

0.640

High

273688

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

8

High-throughput

0.628

High

749790

CADH5
Cadherin-5

2

14

High-throughput

0.628

High

1093003

CDC16
Cell division cycle protein 16 homolog

2

2

High-throughput

0.628

High

1233759

CNDH2
Condensin-2 complex subunit H2

2

1

High-throughput

0.628

High

1316904

NGN3
Neurogenin-3

2

11

High-throughput

0.628

High

1145617

RCN1
Reticulocalbin-1

1

5

High-throughput

0.618

High

995692

ACTC
Actin, alpha cardiac muscle 1

1

20

High-throughput

0.618

High

996765

TBA1B
Tubulin alpha-1B chain

1

5

High-throughput

0.618

High

1316886

TRI36
E3 ubiquitin-protein ligase TRIM36

1

20

High-throughput

0.618

High

1316896

TRIM1
Probable E3 ubiquitin-protein ligase MID2

1

20

Small-scale

0.618

High

549193

CDK4
Cyclin-dependent kinase 4

2

14

High-throughput

0.611

High

1113653

CUL3
Cullin-3

2

12

High-throughput

0.611

High

1280296

DNJB7
DnaJ homolog subfamily B member 7

2

5

High-throughput

0.611

High

1316892

DKK3
Dickkopf-related protein 3

3

6

High-throughput

0.604

High

1316847

T53I1
Tumor protein p53-inducible nuclear protein 1

2

0

High-throughput

0.602

High

1316884

CSN7B
COP9 signalosome complex subunit 7b

2

0

High-throughput

0.602

High

230353

CREB3
Cyclic AMP-responsive element-binding protein 3

2

3

High-throughput

0.601

High

391342

FRIL
Ferritin light chain

2

1

High-throughput

0.601

High

1161144

MK06
Mitogen-activated protein kinase 6

2

20

High-throughput

0.601

High

1316868

NP1L4
Nucleosome assembly protein 1-like 4

2

8

Small-scale

0.601

High

1316869

HAUS7
HAUS augmin-like complex subunit 7

2

0

High-throughput

0.585

High

414188

P53
Cellular tumor antigen p53

2

10

High-throughput

0.584

High

516359

CALM1
Calmodulin-1

1

19

High-throughput

0.575

High

516431

CALM2
Calmodulin-2

1

19

High-throughput

0.575

High

516555

CALM3
Calmodulin-3

1

19

High-throughput

0.575

High

655863

TBG1
Tubulin gamma-1 chain

1

7

Small-scale

0.575

High

1316870

TBA1C
Tubulin alpha-1C chain

1

5

High-throughput

0.575

High

1316872

CAB45
45 kDa calcium-binding protein

1

20

High-throughput

0.575

High

1316846

CNKR1
Connector enhancer of kinase suppressor of ras 1

2

20

High-throughput

0.574

High

1316876

MAD3
Max dimerization protein 3

2

12

High-throughput

0.574

High

1316885

CRAC1
Cartilage acidic protein 1

2

1

High-throughput

0.574

High

1316890

SYIM
Isoleucine--tRNA ligase, mitochondrial

2

3

High-throughput

0.574

High

1316906

EID1
EP300-interacting inhibitor of differentiation 1

2

2

High-throughput

0.574

High

170227

AURKA
Aurora kinase A

2

18

Small-scale

0.571

High

372544

MYC
Myc proto-oncogene protein

2

13

High-throughput

0.571

High

936802

NP1L1
Nucleosome assembly protein 1-like 1

2

8

Small-scale

0.571

High

1050473

UBE3A
Ubiquitin-protein ligase E3A

1

5

Small-scale

0.552

High

1316875

KTNB1
Katanin p80 WD40 repeat-containing subunit B1

2

10

Small-scale

0.552

High

334832

IPO7
Importin-7

2

2

Small-scale

0.549

High

1316897

PNMA2
Paraneoplastic antigen Ma2

2

17

High-throughput

0.549

High

176216

PER2
Period circadian protein homolog 2

1

11

High-throughput

0.536

High

451539

CENPB
Major centromere autoantigen B

1

1

High-throughput

0.536

High

681440

PSA3
Proteasome subunit alpha type-3

1

1

High-throughput

0.536

High

761754

HSP74
Heat shock 70 kDa protein 4

1

9

High-throughput

0.536

High

839316

MTOR
Serine/threonine-protein kinase mTOR

1

6

High-throughput

0.536

High

848675

MAGA9
Melanoma-associated antigen 9

1

11

High-throughput

0.536

High

968987

PRS8
26S proteasome regulatory subunit 8

1

2

High-throughput

0.536

High

1095411

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

9

High-throughput

0.536

High

1095905

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

4

High-throughput

0.536

High

1103711

JIP2
C-Jun-amino-terminal kinase-interacting protein 2

1

5

High-throughput

0.536

High

1134639

NUMA1
Nuclear mitotic apparatus protein 1

1

20

High-throughput

0.536

High

1206942

CEP78
Centrosomal protein of 78 kDa

1

8

High-throughput

0.536

High

1316841

DNJB8
DnaJ homolog subfamily B member 8

1

5

High-throughput

0.536

High

1316848

TRI52
E3 ubiquitin-protein ligase TRIM52

1

15

High-throughput

0.536

High

1316859

ZN333
Zinc finger protein 333

1

2

High-throughput

0.536

High

1316861

LURA1
Leucine rich adaptor protein 1

1

4

High-throughput

0.536

High

447210

NPM
Nucleophosmin

1

5

High-throughput

0.515

High

573570

ENPL
Endoplasmin

1

8

High-throughput

0.515

High

697948

CALR
Calreticulin

1

2

High-throughput

0.515

High

946830

H2B1D
Histone H2B type 1-D

1

6

High-throughput

0.515

High

1128648

ZN460
Zinc finger protein 460

1

0

High-throughput

0.513

High

1316852

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.513

High

1316857

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.513

High

1316866

CSRN1
Cysteine/serine-rich nuclear protein 1

1

0

High-throughput

0.513

High

1316898

INTU
Protein inturned

1

0

High-throughput

0.513

High

967848

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

16

Small-scale

0.501

High

1316845

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

15

High-throughput

0.501

High

229752

CALU
Calumenin

1

5

High-throughput

0.489

High

300792

KRT38
Keratin, type I cuticular Ha8

1

20

High-throughput

0.489

High

335331

M3K6
Mitogen-activated protein kinase kinase kinase 6

1

20

High-throughput

0.489

High

936606

ELL
RNA polymerase II elongation factor ELL

1

4

High-throughput

0.489

High

1062827

QOR
Quinone oxidoreductase

1

1

High-throughput

0.489

High

1105509

OS9
Protein OS-9

1

3

High-throughput

0.489

High

1289352

ST32C
Serine/threonine-protein kinase 32C

1

13

High-throughput

0.489

High

1316842

ZCH10
Zinc finger CCHC domain-containing protein 10

1

2

High-throughput

0.489

High

1316862

ODAD1
Outer dynein arm-docking complex subunit 1

1

20

High-throughput

0.489

High

1316879

ANO3
Anoctamin-3

1

1

High-throughput

0.489

High

1316880

RSH6A
Radial spoke head protein 6 homolog A

1

7

High-throughput

0.489

High

164006

NDC80
Kinetochore protein NDC80 homolog

1

17

High-throughput

0.479

High

174553

TRI66
Tripartite motif-containing protein 66

1

16

High-throughput

0.479

High

186772

P73
Tumor protein p73

1

10

High-throughput

0.479

High

247379

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

9

High-throughput

0.479

High

274657

DNJB6
DnaJ homolog subfamily B member 6

1

4

High-throughput

0.479

High

293996

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.479

High

298935

DNJB5
DnaJ homolog subfamily B member 5

1

2

High-throughput

0.479

High

342954

HERC2
E3 ubiquitin-protein ligase HERC2

1

7

High-throughput

0.479

High

401128

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

11

High-throughput

0.479

High

487516

PARP1
Poly [ADP-ribose] polymerase 1

1

6

High-throughput

0.479

High

606908

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

764883

CTNB1
Catenin beta-1

1

10

Small-scale

0.479

High

941203

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

986559

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

4

High-throughput

0.479

High

1035768

KIF23
Kinesin-like protein KIF23

1

18

High-throughput

0.479

High

1045501

TF65
Transcription factor p65

1

7

High-throughput

0.479

High

1140542

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

1141772

EEA1
Early endosome antigen 1

1

16

High-throughput

0.479

High

1316849

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.479

High

1316854

GASP2
G-protein coupled receptor-associated sorting protein 2

1

1

High-throughput

0.479

High

1316874

THAP7
THAP domain-containing protein 7

1

1

High-throughput

0.479

High

1316881

P63
Tumor protein 63

1

10

High-throughput

0.479

High

1316882

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.479

High

1316883

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

1316887

ANLN
Anillin

1

13

High-throughput

0.479

High

1316888

SMYD2
N-lysine methyltransferase SMYD2

1

3

High-throughput

0.479

High

1316889

HELLS
Lymphoid-specific helicase

1

4

High-throughput

0.479

High

1316893

DIC
Mitochondrial dicarboxylate carrier

1

3

High-throughput

0.479

High

1316900

FZR1
Fizzy-related protein homolog

1

10

High-throughput

0.479

High

1316905

TRI17
E3 ubiquitin-protein ligase TRIM17

1

6

Small-scale

0.479

High

892695

DNLI4
DNA ligase 4

1

0

High-throughput

0.460

High

841825

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

1149327

STIL
SCL-interrupting locus protein

1

0

High-throughput

0.458

High

1161534

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

58865

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

3

High-throughput

0.445

High

107379

F8W118
Nucleosome assembly protein 1 like 1

1

8

High-throughput

0.445

High

214597

WDR62
WD repeat-containing protein 62

1

4

Small-scale

0.445

High

282475

KTNA1
Katanin p60 ATPase-containing subunit A1

1

11

Small-scale

0.445

High

351136

ECD
Protein ecdysoneless homolog

1

4

High-throughput

0.445

High

449750

H2B1J
Histone H2B type 1-J

1

6

Small-scale

0.445

High

679373

DNJB2
DnaJ homolog subfamily B member 2

1

4

High-throughput

0.445

High

717893

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

Small-scale

0.445

High

765699

BMI1
Polycomb complex protein BMI-1

1

17

High-throughput

0.445

High

877693

SL9A3
Sodium/hydrogen exchanger 3

1

4

High-throughput

0.445

High

934849

TERA
Transitional endoplasmic reticulum ATPase

1

5

Small-scale

0.445

High

1033382

CDR2
Cerebellar degeneration-related protein 2

1

1

High-throughput

0.445

High

1315524

KATL2
Katanin p60 ATPase-containing subunit A-like 2

1

12

High-throughput

0.445

High

1316837

FAM9B
Protein FAM9B

1

1

High-throughput

0.445

High

1316838

RNF10
E3 ubiquitin-protein ligase RNF10

1

4

High-throughput

0.445

High

1316840

PNMA1
Paraneoplastic antigen Ma1

1

17

High-throughput

0.445

High

1316853

GCP3
Gamma-tubulin complex component 3

1

4

Small-scale

0.445

High

1316855

SAAL1
Protein SAAL1

1

3

High-throughput

0.445

High

1316863

IPO9
Importin-9

1

2

Small-scale

0.445

High

1316864

GCP6
Gamma-tubulin complex component 6

1

4

Small-scale

0.445

High

1316873

GCP2
Gamma-tubulin complex component 2

1

4

Small-scale

0.445

High

1316877

KIFC1
Kinesin-like protein KIFC1

1

2

Small-scale

0.445

High

1316891

CEP72
Centrosomal protein of 72 kDa

1

3

High-throughput

0.445

High

1316894

GCP4
Gamma-tubulin complex component 4

1

4

Small-scale

0.445

High

1316901

CHIP
E3 ubiquitin-protein ligase CHIP

1

8

Small-scale

0.445

High

176512

GRRE1
Granule associated Rac and RHOG effector protein 1

1

1

High-throughput

0.437

High

565662

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

3

High-throughput

0.437

High

627544

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

1

1

High-throughput

0.437

High

1241903

FBX42
F-box only protein 42

1

15

High-throughput

0.437

High

1316850

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

1

Small-scale

0.437

High

1316899

HECD1
E3 ubiquitin-protein ligase HECTD1

1

12

High-throughput

0.437

High

1316903

SSRG
Translocon-associated protein subunit gamma

1

1

High-throughput

0.437

High

122805

KIF2A
Kinesin-like protein KIF2A

1

0

Small-scale

0.426

High

298198

DCTN3
Dynactin subunit 3

1

0

Small-scale

0.426

High

1239806

MZT2B
Mitotic-spindle organizing protein 2B

1

0

Small-scale

0.426

High

76295

B4DLN1
Mitochondrial dicarboxylate carrier

1

2

High-throughput

0.407

High

91622

C9JA28
Translocon-associated protein subunit gamma

1

1

High-throughput

0.407

High

1103883

PM2P3
Putative postmeiotic segregation increased 2-like protein 3

1

1

High-throughput

0.407

High

1308530

SL9A9
Sodium/hydrogen exchanger 9

1

4

High-throughput

0.407

High

1316843

SL9A6
Sodium/hydrogen exchanger 6

1

4

High-throughput

0.407

High

1316839

SPC24
Kinetochore protein Spc24

3

0

High-throughput

0.347

High

156152

TRAD1
TRAF-type zinc finger domain-containing protein 1

3

0

Small-scale

0.345

High

1316878

TX13A
Testis-expressed protein 13A

2

0

High-throughput

0.328

High

1316895

GPN3
GPN-loop GTPase 3

2

0

High-throughput

0.318

High

1005745

RPP38
Ribonuclease P protein subunit p38

1

0

High-throughput

0.279

Low

1187653

T10IP
Testis-specific protein 10-interacting protein

1

0

High-throughput

0.279

Low

1291030

PACS2
Phosphofurin acidic cluster sorting protein 2

1

0

High-throughput

0.279

Low

1310073

CCD83
Coiled-coil domain-containing protein 83

1

0

High-throughput

0.279

Low

1316858

EAF1
ELL-associated factor 1

1

0

High-throughput

0.249

Low

1316902

SNX7
Sorting nexin-7

1

0

High-throughput

0.249

Low

63765

KRBA1
Protein KRBA1

1

0

High-throughput

0.232

Low

616774

SDC1
Syndecan-1

1

0

High-throughput

0.232

Low

1239002

NIPA3
Magnesium transporter NIPA3

1

0

High-throughput

0.232

Low

1316860

C170L
Cep170-like protein

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025