HitPredict

Interactor 1: UB2E2 (Q96LR5)
Ubiquitin-conjugating enzyme E2 E2 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E2) (UbcH8) (Ubiquitin carrier protein E2) (Ubiquitin-protein ligase E2)
Gene: UBE2E2

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	21965653
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0006974 - DNA damage response
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 201 Hs			1 777
+	Hs
		1282334 UB2E3_HUMAN (1-201): 6.37e-85: 251: 79.71		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		919837 UB2D2_HUMAN (55-200): 2.8e-82: 242: 64.38		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		849423 UB2D1_HUMAN (55-200): 1.23e-81: 240: 61.64		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		851878 UB2E1_HUMAN (28-201): 6.5e-80: 238: 89.71		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		895891 UB2D3_HUMAN (55-200): 1.28e-80: 238: 63.70		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		896527 UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27		BARD1_HUMAN (1-777): 0: 663: 100.00
+	Hs
		829062 UBE2A_HUMAN (54-198): 1.67e-70: 212: 35.86		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		896542 UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27		Q9H4D1_HUMAN (216-431): 1.1e-17: 90: 8.04
+	Hs
		829054 UBE2A_HUMAN (54-198): 1.67e-70: 212: 35.86		SLF1_HUMAN (423-552): 2.06e-17: 89.4: 43.80
+	Hs
		883463 UBE2N_HUMAN (53-200): 2.86e-70: 212: 45.27		RIPK4_HUMAN (216-431): 2.07e-17: 89.2: 7.59